PIMA515072
IRS1 Monoclonal Antibody (J.566.7), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515072-Each-of-1 | In Stock | ₹ 45,646.26 |
PIMA515072 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
IRS1
Classification
Monoclonal
Concentration
708 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.
P35568, P35569, P35570
Gene Symbols
IRS1
Immunogen
Synthetic peptide corresponding to the sequence surrounding Ser612 of human IRS-1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Western Blot
Clone
J.566.7
Conjugate
Unconjugated
Gene
IRS1
Gene Alias
G972R; HIRS-1; Insulin receptor substrate 1; IRS1; IRS-1; IRS1IRM; pp185
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16367, 25467, 3667
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- IRS-1, a major substrate of the insulin receptor, is phosphorylated in response to stimulation of cells by insulin, insulin-like growth factor 1 (IGF-1) and interleukin 4 (IL-4)
- IRS-1 is phosphorylated on serine, threonine and tyrosine residues in a variety of tissues
- An insulin-sensitive serine/threonine kinase casein kinase II mediates a portion of the insulin-stimulated serine/threonine phosphorylation of overexpressed IRS-1 in vivo
- Thr 502 is identified as the major casein kinase II-catalyzed phosphorylation site in rat IRS-1, and Ser 99 is an additional phosphorylation site catalyzed by casein kinase II
- Thus, casein kinase II-catalyzed phosphorylation of IRS-1 may be a component of the intracellular insulin signaling cascade
- IRS-1 contains three putative binding sites for 14-3-3 (Ser 270, Ser 374 and Ser 641) and the motif around Ser 270 is located in the phosphortyrosine binding domain of IRS-1, which is responsible for the interaction with the insulin receptor.
Compare Similar Items
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Antigen: IRS1
Classification: Monoclonal
Concentration: 708 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P35568, P35569, P35570
Gene Symbols: IRS1
Immunogen: Synthetic peptide corresponding to the sequence surrounding Ser612 of human IRS-1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: J.566.7
Conjugate: Unconjugated
Gene: IRS1
Gene Alias: G972R; HIRS-1; Insulin receptor substrate 1; IRS1; IRS-1; IRS1IRM; pp185
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16367, 25467, 3667
Content And Storage: -20°C
Form: Liquid
Antigen:
IRS1
Classification:
Monoclonal
Concentration:
708 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P35568, P35569, P35570
Gene Symbols:
IRS1
Immunogen:
Synthetic peptide corresponding to the sequence surrounding Ser612 of human IRS-1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
J.566.7
Conjugate:
Unconjugated
Gene:
IRS1
Gene Alias:
G972R; HIRS-1; Insulin receptor substrate 1; IRS1; IRS-1; IRS1IRM; pp185
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16367, 25467, 3667
Content And Storage:
-20°C
Form:
Liquid
Antigen: Phospho-TAK1 (Thr184, Thr187)
Classification: Monoclonal
Concentration: 24 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: O43318
Gene Symbols: MAP3K7
Immunogen: Phosphopeptide corresponding to residues surrounding pThr184 and pThr187 of human TAK1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: K.846.3
Conjugate: Unconjugated
Gene: MAP3K7
Gene Alias: B430101B05; C87327; hypothetical protein LOC553788; I79_000697; M3K7; map3k7; map3k7.L; MAPKKK; MEKK7; mitogen activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7 L homeolog; RP1-154G14.1; si:ch211-225h9.1; Tak1; TAK1z; TGF1a; TGF-beta activated kinase 1; TGF-beta-activated kinase 1; TGF-beta-activated kinase TAK1; transforming growth factor beta-activated kinase 1; transforming growth factor-beta-activated kinase 1; XELAEV_18027270mg; xTAK1; zgc:110612
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6885
Content And Storage: -20°C
Form: Liquid
Antigen:
Phospho-TAK1 (Thr184, Thr187)
Classification:
Monoclonal
Concentration:
24 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
O43318
Gene Symbols:
MAP3K7
Immunogen:
Phosphopeptide corresponding to residues surrounding pThr184 and pThr187 of human TAK1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
K.846.3
Conjugate:
Unconjugated
Gene:
MAP3K7
Gene Alias:
B430101B05; C87327; hypothetical protein LOC553788; I79_000697; M3K7; map3k7; map3k7.L; MAPKKK; MEKK7; mitogen activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7 L homeolog; RP1-154G14.1; si:ch211-225h9.1; Tak1; TAK1z; TGF1a; TGF-beta activated kinase 1; TGF-beta-activated kinase 1; TGF-beta-activated kinase TAK1; transforming growth factor beta-activated kinase 1; transforming growth factor-beta-activated kinase 1; XELAEV_18027270mg; xTAK1; zgc:110612
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6885
Content And Storage:
-20°C
Form:
Liquid
Antigen: Bcl-W
Classification: Monoclonal
Concentration: 107 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P70345, Q92843
Gene Symbols: BCL2L2
Immunogen: Synthetic peptide corresponding to residues surrounding alanine 39 of Bcl-w
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: F.584.7
Conjugate: Unconjugated
Gene: BCL2L2
Gene Alias: Apoptosis regulator Bcl-W; AW048834; BCL2 like 2; BCL2L2; BCL2-L-2; BCL2-like 2; BCL2-like 2 protein; Bcl-2-like protein 2; Bcl2-like protein 2; BCLW; BCL-W; BCL-WEL; BCL-WS; c98; Gtrgal2; Gtrosa41; Kiaa0271; PPP1R51; protein phosphatase 1, regulatory subunit 51
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12050, 599, 60434
Content And Storage: -20°C
Form: Liquid
Antigen:
Bcl-W
Classification:
Monoclonal
Concentration:
107 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P70345, Q92843
Gene Symbols:
BCL2L2
Immunogen:
Synthetic peptide corresponding to residues surrounding alanine 39 of Bcl-w
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
F.584.7
Conjugate:
Unconjugated
Gene:
BCL2L2
Gene Alias:
Apoptosis regulator Bcl-W; AW048834; BCL2 like 2; BCL2L2; BCL2-L-2; BCL2-like 2; BCL2-like 2 protein; Bcl-2-like protein 2; Bcl2-like protein 2; BCLW; BCL-W; BCL-WEL; BCL-WS; c98; Gtrgal2; Gtrosa41; Kiaa0271; PPP1R51; protein phosphatase 1, regulatory subunit 51
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12050, 599, 60434
Content And Storage:
-20°C
Form:
Liquid
Antigen: COX4
Classification: Monoclonal
Concentration: 331 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P00423, P10888, P13073, Q95283
Gene Symbols: COX4I1, LOC100624067
Immunogen: Synthetic peptide corresponding to residues surrounding Lys29 of human COX IV
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Bovine, Human, Non-human Primate, Porcine, Rat, Zebrafish
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: K.473.4
Conjugate: Unconjugated
Gene: COX4I1
Gene Alias: AL024441; C16orf2; C16orf4; COX; cox iv; COX IV-1; Cox IV-2; Cox4; COX4 neighbor; Cox4-1; COX4-2; Cox4a; COX4AL; Cox4b; COX4I1; cox4i1.S; Cox4i2; COX4L2; COX4NB; coxiv; COXIV-1; CoxIV-2; cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; cytochrome c oxidase subunit 4 isoform 2, mitochondrial; cytochrome c oxidase subunit 4I1; cytochrome c oxidase subunit 4I2; cytochrome c oxidase subunit IV; cytochrome c oxidase subunit IV isoform 1; cytochrome c oxidase subunit IV isoform 1 precursor; cytochrome c oxidase subunit IV isoform 1 S homeolog; cytochrome c oxidase subunit IV isoform 2; cytochrome c oxidase subunit IV isoform 2 (lung); cytochrome c oxidase subunit IV precursor EC 1.9.3.1; cytochrome c oxidase subunit IV-like 2; cytochrome c oxidase, subunit 4a; cytochrome c oxidase, subunit 4b; cytochrome c oxidase, subunit IV; cytochrome c oxidase, subunit IVa; cytochrome c oxidase, subunit IVb; cytochrome c oxydase subunit 4; dJ857M17.2; EMC8; ER membrane protein complex subunit 8; FAM158B; family with sequence similarity 158, member B; FLJ23483; hypothetical protein MGC73355; IV-1; mg:bb02d03; MGC72016; Neighbor of COX4; NOC4; Protein FAM158B; XELAEV_18024950mg; zgc:110058; zgc:73355
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100624067, 1327, 281090, 29445, 326975
Content And Storage: -20°C
Form: Liquid
Antigen:
COX4
Classification:
Monoclonal
Concentration:
331 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P00423, P10888, P13073, Q95283
Gene Symbols:
COX4I1, LOC100624067
Immunogen:
Synthetic peptide corresponding to residues surrounding Lys29 of human COX IV
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Non-human Primate, Porcine, Rat, Zebrafish
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
K.473.4
Conjugate:
Unconjugated
Gene:
COX4I1
Gene Alias:
AL024441; C16orf2; C16orf4; COX; cox iv; COX IV-1; Cox IV-2; Cox4; COX4 neighbor; Cox4-1; COX4-2; Cox4a; COX4AL; Cox4b; COX4I1; cox4i1.S; Cox4i2; COX4L2; COX4NB; coxiv; COXIV-1; CoxIV-2; cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; cytochrome c oxidase subunit 4 isoform 2, mitochondrial; cytochrome c oxidase subunit 4I1; cytochrome c oxidase subunit 4I2; cytochrome c oxidase subunit IV; cytochrome c oxidase subunit IV isoform 1; cytochrome c oxidase subunit IV isoform 1 precursor; cytochrome c oxidase subunit IV isoform 1 S homeolog; cytochrome c oxidase subunit IV isoform 2; cytochrome c oxidase subunit IV isoform 2 (lung); cytochrome c oxidase subunit IV precursor EC 1.9.3.1; cytochrome c oxidase subunit IV-like 2; cytochrome c oxidase, subunit 4a; cytochrome c oxidase, subunit 4b; cytochrome c oxidase, subunit IV; cytochrome c oxidase, subunit IVa; cytochrome c oxidase, subunit IVb; cytochrome c oxydase subunit 4; dJ857M17.2; EMC8; ER membrane protein complex subunit 8; FAM158B; family with sequence similarity 158, member B; FLJ23483; hypothetical protein MGC73355; IV-1; mg:bb02d03; MGC72016; Neighbor of COX4; NOC4; Protein FAM158B; XELAEV_18024950mg; zgc:110058; zgc:73355
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100624067, 1327, 281090, 29445, 326975
Content And Storage:
-20°C
Form:
Liquid