PIMA515228

Phospho-JNK1/JNK2 (Thr183, Tyr185) Monoclonal Antibody (E.665.10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515228-Each-of-1 In Stock ₹ 50,822.64

PIMA515228 - Each of 1

₹ 50,822.64

In Stock

Quantity

1

Base Price: ₹ 50,822.64

GST (18%): ₹ 9,148.075

Total Price: ₹ 59,970.715

Antigen

Phospho-JNK1/JNK2 (Thr183, Tyr185)

Classification

Monoclonal

Concentration

591 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

P45983, P45984, P49185, P49186, Q91Y86, Q9WTU6

Gene Symbols

MAPK8, MAPK9

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding pThr183/Tyr185 of human SAPK/JNK

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Hamster, Human, Mouse, Rat, Yeast

Product Type

Antibody

Isotype

IgG1

Applications

ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

E.665.10

Conjugate

Unconjugated

Gene

MAPK8

Gene Alias

AI849689; AI851083; C-jun kinase; c-Jun kinase 2; c-Jun N-terminal kinase 1; c-Jun N-terminal kinase 2; I79_012561; JNK; JNK 55; JNK/SAPK alpha; JNK1; JNK1 beta1 protein kinase; JNK1A2; JNK2; JNK21B1/2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; JNK-46; JNK-55; Jun kinase; JUN N-terminal kinase; MAP kinase 8; MAP kinase 9; MAPK; MAPK 8; MAPK 9; Mapk8; Mapk9; mitogen activated protein kinase 8; mitogen activated protein kinase 9; mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 9; OTTHUMP00000019552; p54 gamma; p54a; p54-alpha; p54aSAPK; Phospho-JNK; PRKM; PRKM8; Prkm9; protein kinase JNK1; protein kinase mitogen-activated 8; protein kinase, mitogen-activated 9; SAPK; SAPK 1; SAPK gamma; SAPK1; SAPK1A; SAPK1c; SAPK-alpha; stress activated protein kinase alpha II; stress-activated protein kinase 1; stress-activated protein kinase 1a; Stress-activated protein kinase 1c; stress-activated protein kinase JNK1; Stress-activated protein kinase JNK2

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100764964, 100771734, 116554, 26419, 26420, 50658, 5599, 5601

Content And Storage

-20°C

Form

Liquid

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Description

  • Antibodies to this protein (and modification) were previously sold as part of a Thermo Scientific Cellomics High Content Screening Kit
  • This replacement antibody is now recommended for researchers who need an antibody for high content cell based assays
  • It has been thoroughly tested and validated for cellular immunofluorescence (IF) applications
  • Further optimization including the selection of the most appropriate fluorescent Dylight conjugated secondary antibody may have to be performed for your high content assay
  • It is not recommended to aliquot this antibody
  • C-Jun N-terminal Kinase (JNK) is also known as Mitogen-activated protein kinase (MAPK8)
  • It belongs to the MAPK superfamily of stress-activated protein kinases
  • MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus
  • JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development
  • JNK pathways are activated by stress and inflammatory signals
  • JNK is expressed as ten different isoforms due to differential mRNA splicing
  • The predominant forms are JNK1 and JNK2.

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Img

Thermo Scientific

PIMA515228

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Antigen:
Phospho-JNK1/JNK2 (Thr183, Tyr185)

Classification:
Monoclonal

Concentration:
591 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P45983, P45984, P49185, P49186, Q91Y86, Q9WTU6

Gene Symbols:
MAPK8, MAPK9

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pThr183/Tyr185 of human SAPK/JNK

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Hamster, Human, Mouse, Rat, Yeast

Product Type:
Antibody

Isotype:
IgG1

Applications:
ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
E.665.10

Conjugate:
Unconjugated

Gene:
MAPK8

Gene Alias:
AI849689; AI851083; C-jun kinase; c-Jun kinase 2; c-Jun N-terminal kinase 1; c-Jun N-terminal kinase 2; I79_012561; JNK; JNK 55; JNK/SAPK alpha; JNK1; JNK1 beta1 protein kinase; JNK1A2; JNK2; JNK21B1/2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; JNK-46; JNK-55; Jun kinase; JUN N-terminal kinase; MAP kinase 8; MAP kinase 9; MAPK; MAPK 8; MAPK 9; Mapk8; Mapk9; mitogen activated protein kinase 8; mitogen activated protein kinase 9; mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 9; OTTHUMP00000019552; p54 gamma; p54a; p54-alpha; p54aSAPK; Phospho-JNK; PRKM; PRKM8; Prkm9; protein kinase JNK1; protein kinase mitogen-activated 8; protein kinase, mitogen-activated 9; SAPK; SAPK 1; SAPK gamma; SAPK1; SAPK1A; SAPK1c; SAPK-alpha; stress activated protein kinase alpha II; stress-activated protein kinase 1; stress-activated protein kinase 1a; Stress-activated protein kinase 1c; stress-activated protein kinase JNK1; Stress-activated protein kinase JNK2

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100764964, 100771734, 116554, 26419, 26420, 50658, 5599, 5601

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515229

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Antigen:
Phospho-p53 (Ser15)

Classification:
Monoclonal

Concentration:
765 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P04637

Gene Symbols:
Tp53

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pSer15 of human p53

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
C.381.0

Conjugate:
Unconjugated

Gene:
Tp53

Gene Alias:
Antigen NY-CO-13; bbl; BCC7; bfy; bhy; cellular tumor antigen p53; Cys 51 Stop; EGK_08142; FLJ92943; HGNC11998; I79_002739; LFS1; Li-Fraumeni syndrome; mutant p53; mutant tumor protein 53; OTTMUSP00000006194; p44; p53; p53 cellular tumor antigen; p53 protein; p53 tumor suppressor; p53 tumor suppressor phosphoprotein; phosphoprotein p53; Tp53; tp53.L; transformation related protein 53; transformation-related protein 53; Trp248; Trp53; tumor protein 53; tumor protein p53; tumor protein p53 (Li-Fraumeni syndrome); tumor protein p53 L homeolog; tumor suppressor p53; tumor suppressor p53 phosphoprotein; tumor suppressor protein p53; tumor supressor p53; Tumour Protein p53; XELAEV_180196761mg; Xp53; Xrel3

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7157

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515230

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Antigen:
Phospho-BAD (Ser112)

Classification:
Monoclonal

Concentration:
1589 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
O35147, Q61337, Q92934

Gene Symbols:
BAD

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pSer112 of mouse Bad

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
E.635.2

Conjugate:
Unconjugated

Gene:
BAD

Gene Alias:
AI325008; BAD; Bbc2; Bbc6; Bcl2 antagonist of cell death; BCL2 associated agonist of cell death; bcl-2 associated death agonist; Bcl2-antagonist of cell death; BCL2-antagonist of cell death protein; bcl2-associated agonist of cell death; bcl2-associated death promoter; bcl-2-binding component 6; BCL2-binding component 6; BCL2-binding protein; BCL2L8; bcl2-L-8; Bcl-2-like protein 8; BCL-X/BCL-2 binding protein; bcl-XL/Bcl-2-associated death promoter; hypothetical protein LOC615013; OTTMUSP00000017561; OTTMUSP00000022400

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12015, 572, 64639

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515232

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Antigen:
TRIM5 alpha

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
Q9C035

Gene Symbols:
Trim5

Immunogen:
Purified recombinant fragment of human trim5 alpha expressed in E. Coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
3B11H2

Conjugate:
Unconjugated

Gene:
Trim5

Gene Alias:
EG667823; Gm8833; HGNC:16276; OTTHUMP00000069812; RING finger protein 88; RING-type E3 ubiquitin transferase TRIM5; RNF88; TRIM5; Trim5 alpha; TRIM5 alpha; predicted E3 ubiquiting ligase; TRIM5 gamma; predicted E3 ubiquiting ligase; trim5a; TRIM5alpha; tripartite motif containing 5; tripartite motif containing 5 transcript variant iota; tripartite motif containing 5 transcript variant kappa; tripartite motif protein TRIM5; tripartite motif-containing 5; tripartite motif-containing 5 alpha isoform; tripartite motif-containing 5 gamma isoform; tripartite motif-containing 5/cyclophilin A fusion protein; tripartite motif-containing protein 5; tripartite motif-containing protein 5 isoform alpha

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
85363

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid