PIMA515469
Nanog Monoclonal Antibody (1E6C4), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515469-Each-of-1 | In Stock | ₹ 53,047.20 |
PIMA515469 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,047.20
GST (18%): ₹ 9,548.496
Total Price: ₹ 62,595.696
Antigen
Nanog
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
Q9H9S0
Gene Symbols
NANOG
Immunogen
Purified recombinant fragment of NANOG (aa20-166) expressed in E. Coli.
Regulatory Status
RUO
Gene ID (Entrez)
79923
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Immunocytochemistry, Western Blot
Clone
1E6C4
Conjugate
Unconjugated
Gene
NANOG
Gene Alias
2410002E02Rik; early embryo specific expression NK family; early embryo specific expression NK-type homeobox protein; Ecat4; ENK; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog; Nanog homeobox
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15469 targets NANOG in indirect ELISA, IF and WB applications and shows reactivity with Human samples
- The MA5-15469 immunogen is purified recombinant fragment of NANOG (aa20-166) expressed in E
- Coli.<br>
- MA5-15469 detects NANOG which has a predicted molecular weight of approximately 35kDa
- NANOG (Nanog homeobox) is a divergent homeodomain protein that directs pluripotency and differentiation of undifferentiated embryonic stem cells
- NANOG mRNA is present in pluripotent mouse and human cell lines, and absent from differentiated cells
- Human NANOG protein shares 52% overall amino acid identity with the mouse protein, and 85% identity in the homeodomain
- Human NANOG maps to gene locus 12p13.31, while the mouse NANOG maps to gene loci 6 F2
- Murine embryonic NANOG expression is detected in the inner cell mass of the blastocyst
- Research studies have shown that high levels of human NANOG expression in the undifferentiated N-Tera embryonal carcinoma cell line
- Further, NANOG is a transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal
- The role of NANOG in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases
- Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing POU5F1 (also known as Oct-4), another germline-specific transcription factor, and the transcription factors Sox2, Klf4 and Lin28 along with c-Myc in mouse fibroblasts
- Experiments have demonstrated that iPS cells could be generated using expression plasmids expressing NANOG, Sox2, KlfF4 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine
- When overexpressed, NANOG promotes cells to enter into S phase and proliferation
- Diseases associated with dysfunction in the NANOG protein include tetracarcinoma and germ cell/embryonal cancer.
Compare Similar Items
Show Difference
Antigen: Nanog
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: Q9H9S0
Gene Symbols: NANOG
Immunogen: Purified recombinant fragment of NANOG (aa20-166) expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 79923
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunocytochemistry, Western Blot
Clone: 1E6C4
Conjugate: Unconjugated
Gene: NANOG
Gene Alias: 2410002E02Rik; early embryo specific expression NK family; early embryo specific expression NK-type homeobox protein; Ecat4; ENK; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog; Nanog homeobox
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
Nanog
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
Q9H9S0
Gene Symbols:
NANOG
Immunogen:
Purified recombinant fragment of NANOG (aa20-166) expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
79923
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Western Blot
Clone:
1E6C4
Conjugate:
Unconjugated
Gene:
NANOG
Gene Alias:
2410002E02Rik; early embryo specific expression NK family; early embryo specific expression NK-type homeobox protein; Ecat4; ENK; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog; Nanog homeobox
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: SKP2
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: Q13309
Gene Symbols: SKP2
Immunogen: Purified recombinant fragment of SKP2 (aa1-130) expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 6502
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Western Blot
Clone: 6G9D10
Conjugate: Unconjugated
Gene: SKP2
Gene Alias: 4930500A04Rik; CDK2/cyclin A-associated protein p45; cyclin A/CDK2-associated protein p45; Cyclin-A/CDK2-associated protein p45; FBL1; F-box protein Skp2; F-box/LRR-repeat protein 1; F-box/WD-40 protein 1; FBXL1; FLB1; FWD1; MGC1366; OTTHUMP00000221389; p45; p45skp2; RGD1562456; Skp2; S-phase kinase-associated protein 2; S-phase kinase-associated protein 2 (p45); S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
SKP2
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
Q13309
Gene Symbols:
SKP2
Immunogen:
Purified recombinant fragment of SKP2 (aa1-130) expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
6502
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Western Blot
Clone:
6G9D10
Conjugate:
Unconjugated
Gene:
SKP2
Gene Alias:
4930500A04Rik; CDK2/cyclin A-associated protein p45; cyclin A/CDK2-associated protein p45; Cyclin-A/CDK2-associated protein p45; FBL1; F-box protein Skp2; F-box/LRR-repeat protein 1; F-box/WD-40 protein 1; FBXL1; FLB1; FWD1; MGC1366; OTTHUMP00000221389; p45; p45skp2; RGD1562456; Skp2; S-phase kinase-associated protein 2; S-phase kinase-associated protein 2 (p45); S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: STAT3
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: P40763
Gene Symbols: STAT3
Immunogen: Purified recombinant fragment of STAT3 expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 6774
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunohistochemistry, Western Blot
Clone: 7G3H4
Conjugate: Unconjugated
Gene: STAT3
Gene Alias: 1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
STAT3
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
P40763
Gene Symbols:
STAT3
Immunogen:
Purified recombinant fragment of STAT3 expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
6774
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Western Blot
Clone:
7G3H4
Conjugate:
Unconjugated
Gene:
STAT3
Gene Alias:
1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: PEG10
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: Q86TG7
Gene Symbols: PEG10
Immunogen: Purified recombinant fragment of human PEG10 expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 23089
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunohistochemistry, Western Blot
Clone: 4C10A7
Conjugate: Unconjugated
Gene: PEG10
Gene Alias: 2-Mar; AA407948; EDR; embryonal carcinoma differentiation regulated; embryonal carcinoma differentiation regulated protein; Embryonal carcinoma differentiation-regulated protein; HB-1; KIAA1051; Mammalian retrotransposon-derived protein 2; MAR2; Mart2; MEF3 like 1; MEF3L; Mef3l1; MEF3-like protein 1; MyEF-3; MyEF-3 like; myelin expression factor 3; Myelin expression factor 3-like protein 1; paternally expressed 10; paternally expressed gene 10 protein; PEG10; Retrotransposon gag domain-containing protein 3; retrotransposon-derived gag-like polyprotein; Retrotransposon-derived protein PEG10; retrotransposon-derived protein PEG10-like; RGAG3; Ty3/Gypsy-like protein
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
PEG10
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
Q86TG7
Gene Symbols:
PEG10
Immunogen:
Purified recombinant fragment of human PEG10 expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
23089
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Western Blot
Clone:
4C10A7
Conjugate:
Unconjugated
Gene:
PEG10
Gene Alias:
2-Mar; AA407948; EDR; embryonal carcinoma differentiation regulated; embryonal carcinoma differentiation regulated protein; Embryonal carcinoma differentiation-regulated protein; HB-1; KIAA1051; Mammalian retrotransposon-derived protein 2; MAR2; Mart2; MEF3 like 1; MEF3L; Mef3l1; MEF3-like protein 1; MyEF-3; MyEF-3 like; myelin expression factor 3; Myelin expression factor 3-like protein 1; paternally expressed 10; paternally expressed gene 10 protein; PEG10; Retrotransposon gag domain-containing protein 3; retrotransposon-derived gag-like polyprotein; Retrotransposon-derived protein PEG10; retrotransposon-derived protein PEG10-like; RGAG3; Ty3/Gypsy-like protein
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1