PIMA515521

alpha-1 Antitrypsin Monoclonal Antibody (2B12), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515521-Each-of-1 In Stock ₹ 53,047.20

PIMA515521 - Each of 1

₹ 53,047.20

In Stock

Quantity

1

Base Price: ₹ 53,047.20

GST (18%): ₹ 9,548.496

Total Price: ₹ 62,595.696

Antigen

alpha-1 Antitrypsin

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

P01009, P07758

Gene Symbols

SERPINA1, Serpina1a

Immunogen

Purified recombinant fragment of human AAT expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

20700, 5265

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Western Blot

Clone

2B12

Conjugate

Unconjugated

Gene

SERPINA1

Gene Alias

a-1 AT; A1A; a1-antitrypsin; A1AT; AAT; Aat2; Aat-2; alpha 1 antitrypsin; alpha-1 antitrypsin; alpha-1 protease inhibitor; Alpha-1 protease inhibitor 1; alpha-1-antiproteinase; Alpha-1-antitrypsin; alpha-1-antitrypsin (protease inhibitor); alpha-1-antitrypsin 1-1; alpha-1-antitrypsin 2; alpha-1-antitrypsin null; alpha1AT; alpha-1-protease inhibitor; alpha-1-proteinase inhibitor; Digestive Zymogen; Dom1; MGC23330; MGC9222; PI; PI1; PRO0684; PRO2209; PRO2275; protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin; protease inhibitor 1 (anti-elastase, antitrypsin, alpha-1); Protease Serine 1; serine (or cysteine) peptidase inhibitor, clade A, member 1A; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; serine (or cysteine) proteinase inhibitor, clade A (alpha-1antiproteinase, antitrypsin), member 1; serine (or cysteine) proteinase inhibitor, clade A, member 1; serine (or cysteine) proteinase inhibitor, clade A, member 1a; Serine Protease 1; serine protease inhibitor 1-1; Serine protease inhibitor A1a; serine protease inhibitor alpha 1; serine proteinase inhibitor, clade A, member 1; serpin A1; Serpin A1a; serpin family A member 1; serpin peptidase inhibitor clade A member 1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; SERPINA1; Serpina1a; Short peptide from AAT; SPAAT; Spi1; Spi1-1; Spi1-3; TRP1; TRY1

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Related Products

Img

Thermo Scientific

PIMA515341

--

Img

Thermo Scientific

PIMA515568

--

Img

Thermo Scientific

PIMA515815

--

Img

Thermo Scientific

PIMA513685

--

Img

Thermo Scientific

PIMA515803

--

Img

Thermo Scientific

PIMA515804

--

Img

Thermo Scientific

PIMA515531

--

Img

Thermo Scientific

PIMA515478

--

Description

  • MA5-15521 targets AAT in indirect ELISA, WB applications and shows reactivity with Human and mouse samples
  • The MA5-15521 immunogen is purified recombinant fragment of human AAT expressed in E
  • Coli
  • MA5-15521 detects AAT which has a predicted molecular weight of approximately 47kDa
  • Alpha-1-AT is synthesized in the liver and it acts as an inhibitor of proteases such as trypsin, elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin, which may be released during inflammatory reactions in the lung
  • In the absence of alpha-1-AT, these enzymes are not inhibited and they may digest pulmonary parenchyma
  • Alpha-1-AT deficiency is associated with chronic obstructive lung disease (emphysema) and less frequently with hepatic cirrhosis in infants and respiratory distress of the newborn
  • Increase in alpha-1-AT occurs as an acute phase response to tissue necrosis and inflammation
  • Serum level of alpha-1-AT is elevated in rheumatoid arthritis, bacterial infections, vasculitis, and carcinomatosis.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA515521

--


Antigen:
alpha-1 Antitrypsin

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P01009, P07758

Gene Symbols:
SERPINA1, Serpina1a

Immunogen:
Purified recombinant fragment of human AAT expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
20700, 5265

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
2B12

Conjugate:
Unconjugated

Gene:
SERPINA1

Gene Alias:
a-1 AT; A1A; a1-antitrypsin; A1AT; AAT; Aat2; Aat-2; alpha 1 antitrypsin; alpha-1 antitrypsin; alpha-1 protease inhibitor; Alpha-1 protease inhibitor 1; alpha-1-antiproteinase; Alpha-1-antitrypsin; alpha-1-antitrypsin (protease inhibitor); alpha-1-antitrypsin 1-1; alpha-1-antitrypsin 2; alpha-1-antitrypsin null; alpha1AT; alpha-1-protease inhibitor; alpha-1-proteinase inhibitor; Digestive Zymogen; Dom1; MGC23330; MGC9222; PI; PI1; PRO0684; PRO2209; PRO2275; protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin; protease inhibitor 1 (anti-elastase, antitrypsin, alpha-1); Protease Serine 1; serine (or cysteine) peptidase inhibitor, clade A, member 1A; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; serine (or cysteine) proteinase inhibitor, clade A (alpha-1antiproteinase, antitrypsin), member 1; serine (or cysteine) proteinase inhibitor, clade A, member 1; serine (or cysteine) proteinase inhibitor, clade A, member 1a; Serine Protease 1; serine protease inhibitor 1-1; Serine protease inhibitor A1a; serine protease inhibitor alpha 1; serine proteinase inhibitor, clade A, member 1; serpin A1; Serpin A1a; serpin family A member 1; serpin peptidase inhibitor clade A member 1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; SERPINA1; Serpina1a; Short peptide from AAT; SPAAT; Spi1; Spi1-1; Spi1-3; TRP1; TRY1

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515522

--


Antigen:
MPS1

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P42677

Gene Symbols:
RPS27

Immunogen:
Purified recombinant fragment of MPS1 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
6232

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry

Clone:
4A12

Conjugate:
Unconjugated

Gene:
RPS27

Gene Alias:
3200001M24Rik; 40S ribosomal protein S27; metallopanstimulin 1; Metallopan-stimulin 1; MPS1; MPS-1; RGD:621045}; ribosomal protein S27; RP11-422P24.3; rps27; rps27 {ECO:0000312; S27; S27-1; Small ribosomal subunit protein eS27

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515523

--


Antigen:
MPS1

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P42677, Q6ZWU9

Gene Symbols:
RPS27

Immunogen:
Purified recombinant fragment of MPS1 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
57294, 6232

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunocytochemistry

Clone:
7E3

Conjugate:
Unconjugated

Gene:
RPS27

Gene Alias:
3200001M24Rik; 40S ribosomal protein S27; metallopanstimulin 1; Metallopan-stimulin 1; MPS1; MPS-1; RGD:621045}; ribosomal protein S27; RP11-422P24.3; rps27; rps27 {ECO:0000312; S27; S27-1; Small ribosomal subunit protein eS27

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515526

--


Antigen:
TBX5

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
Q99593

Gene Symbols:
TBX5

Immunogen:
Purified recombinant fragment of TBX5 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
6910

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
7B11

Conjugate:
Unconjugated

Gene:
TBX5

Gene Alias:
HOS; T-box 5; T-box protein 5; T-box transcription factor TBX5; TBX5

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1