PIMA515544

WNT1 Monoclonal Antibody (10C8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515544-Each-of-1 In Stock ₹ 50,266.50

PIMA515544 - Each of 1

₹ 50,266.50

In Stock

Quantity

1

Base Price: ₹ 50,266.50

GST (18%): ₹ 9,047.97

Total Price: ₹ 59,314.47

Antigen

WNT1

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

P04426, P04628

Gene Symbols

WNT1

Immunogen

Purified recombinant fragment of WNT1 expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

22408, 7471

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone

10C8

Conjugate

Unconjugated

Gene

WNT1

Gene Alias

BMND16; INT1; Int-1; murine mammary tumor virus integration site; OI15; Proto-oncogene Int-1; proto-oncogene Int-1 homolog; proto-oncogene protein Wnt-1; proto-oncogene Wnt-1; sw; swaying; wingless-related MMTV integration site 1; Wingless-type MMTV integration site 1 homolog; Wingless-type MMTV integration site 1, homolog; wingless-type MMTV integration site family member 1; wingless-type MMTV integration site family, member 1; wingless-type MMTV integration site family, member 1 (oncogene INT1); Wnt family member 1; Wnt1; Wnt-1

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15544 targets WNT1 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human and mouse samples
  • The MA5-15544 immunogen is purified recombinant fragment of WNT1 expressed in E
  • Coli
  • MA5-15544 detects WNT1 which has a predicted molecular weight of approximately 41kDa
  • Wnt proteins constitute a family of secreted glyocoproteins that activate signal transduction pathways to mediate tissue homeostasis, cell fate, cell proliferation, and self-renewal
  • The canonical signaling pathway is initiated upon Wnt binding to a Frizzled family receptor and an LRP5/LRP6 coreceptor, which leads to activation of the beta-catenin cascade
  • Non-canonical Wnt signals are activated by binding to a Frizzled family receptor and ROR2 coreceptor
  • Extensive research has shown that deregulation of these pathways or its components can lead to cancer
  • Human Wnt-1 is encoded as a 370 amino acid precursor that, upon secretion, is cleaved into a 343 amino acid (42 kDa) mature form
  • At the amino acid level, mature human Wnt-1 is approximately 99% identical to mature mouse Wnt-1
  • Depending on the tissue, Wnt-1 can activate the canonical and non-canonical signaling pathways
  • Studies have demonstrated its involvement in a variety of functions, including embryonic development and carcinogenesis
  • Wnt-1 signaling can also induce the phosphorylation and subsequent degradation of c-Myb.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA515544

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Antigen:
WNT1

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P04426, P04628

Gene Symbols:
WNT1

Immunogen:
Purified recombinant fragment of WNT1 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
22408, 7471

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
10C8

Conjugate:
Unconjugated

Gene:
WNT1

Gene Alias:
BMND16; INT1; Int-1; murine mammary tumor virus integration site; OI15; Proto-oncogene Int-1; proto-oncogene Int-1 homolog; proto-oncogene protein Wnt-1; proto-oncogene Wnt-1; sw; swaying; wingless-related MMTV integration site 1; Wingless-type MMTV integration site 1 homolog; Wingless-type MMTV integration site 1, homolog; wingless-type MMTV integration site family member 1; wingless-type MMTV integration site family, member 1; wingless-type MMTV integration site family, member 1 (oncogene INT1); Wnt family member 1; Wnt1; Wnt-1

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Img

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PIMA515546

--


Antigen:
TEC

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P42680

Gene Symbols:
Tec

Immunogen:
Purified recombinant fragment of TEC expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
100124696, 7006

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
3A5

Conjugate:
Unconjugated

Gene:
Tec

Gene Alias:
cytoplasmic tyrosine kinase, Dscr28C related; MGC126760; MGC126762; PSCTK4; TEC; tec protein tyrosine kinase; tyrosine-protein kinase Tec

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

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PIMA515548

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Antigen:
TrkC

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
Q16288

Gene Symbols:
Ntrk3

Immunogen:
Purified recombinant extracellular fragment of human NTRK3 (aa32-429) fused with hIgGFc tag expressed in HEK293 cells.

Regulatory Status:
RUO

Gene ID (Entrez):
4916

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
4G5

Conjugate:
Unconjugated

Gene:
Ntrk3

Gene Alias:
AW125844; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp145(trkC); GP145-TrkC; neural receptor protein-tyrosine kinase (trkC); neurotrophic receptor tyrosine kinase 3; Neurotrophic tyrosine kinase receptor type 3; neurotrophic tyrosine kinase, receptor, type 3; neurotrophin-3; NT-3 growth factor receptor; NTRK3; Ntrk3_tv3; TrkC; trk-C; trkC tyrosine kinase; tyrosine kinase receptor; tyrosine kinase receptor C

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

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PIMA515550

--


Antigen:
VEGF Receptor 1

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P17948

Gene Symbols:
FLT1

Immunogen:
Purified recombinant extracellular fragment of human FLT1 fused with hIgGFc tag expressed in HEK293 cells.

Regulatory Status:
RUO

Gene ID (Entrez):
2321

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
3D10

Conjugate:
Unconjugated

Gene:
FLT1

Gene Alias:
AI323757; embryonic receptor kinase 2; Emrk2; FLT; FLT1; FLT-1; fms related tyrosine kinase 1; FMS-like tyrosine kinase 1; FMS-related tyrosine kinase 1; Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor); FRT; i21; sFlt1; soluble VEGFR 1; sVEGFR 1; Tyrosine-protein kinase FRT; tyrosine-protein kinase receptor FLT; Vascular endothelial growth factor receptor 1; vascular endothelial growth factor receptor-1; vascular permeability factor receptor; VEGF R1; VEGFR1; VEGFR-1

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1