PIMA515588
FAK Monoclonal Antibody (10H7), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515588-Each-of-1 | In Stock | ₹ 48,469.74 |
PIMA515588 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,469.74
GST (18%): ₹ 8,724.553
Total Price: ₹ 57,194.293
Antigen
FAK
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
P34152, Q05397
Gene Symbols
PTK2
Immunogen
Purified recombinant fragment of human FAK expressed in E. Coli.
Regulatory Status
RUO
Gene ID (Entrez)
14083, 5747
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone
10H7
Conjugate
Unconjugated
Gene
PTK2
Gene Alias
CG10023; CG10023-PA; CG10023-PB; CG10023-PC; CG10023-PD; CG10023-PF; CG10023-PG; CT28129; DFAK; DFak56; Dmel\CG10023; Dmel_CG10023; DmFAK; EC 2.7.10.2; Fadk; FADK 1; Fak; Fak1; Fak56; fak56D; FAK65D; Fak-PA; Fak-PB; Fak-PC; Fak-PD; Fak-PF; Fak-PG; FAK-related non-kinase polypeptide; focal adhesion kinase; Focal adhesion kinase 1; focal adhesion kinase homolog; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase pp125FAK; focal adhesion kinase-related nonkinase; focal ashension kinase 1; FRNK; I79_019430; Kiaa4203; mKIAA4203; p125FAK; p41/p43FRNK; pFAK; pp125 PTK2; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; protein tyrosine kinase 2; protein tyrosine kinase 2 L homeolog; protein-tyrosine kinase; protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2; ptk2.L; tyrosine kinase; XELAEV_18032408mg; XPFAK
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15588 targets FAK in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human and mouse samples
- The MA5-15588 immunogen is purified recombinant fragment of human FAK expressed in E
- Coli
- MA5-15588 detects FAK which has a predicted molecular weight of approximately 119kDa
- Focal Adhesion Kinase (FAK) is a 125 kDa non-receptor protein tyrosine kinase that acts as a substrate for Src and is a key element of integrin signaling
- FAK plays an important role in cell spreading, differentiation, migration, cell death, and acceleration of the G1 to S phase transition of the cell cycle
- FAK has a central catalytic domain and a C-terminal tail that localizes it to focal adhesions, which are sites where cells attach to the extracellular matrix via surface integrin receptors
- Increased FAK tyrosine phosphorylation occurs upon integrin engagement with fibronectin
- Adhesion of murine NIH3T3 fibroblasts to fibronectin promotes association of the Grb2 adapter protein and c-Src PTK with FAK in vivo, and also results in activation of the ERK2 MAP kinase
- In v-Src-transformed NIH3T3, the association of v-Src, Grb2, and Sos with FAK is independent of cell adhesion to fibronectin
- In vitro the Grb2 SH2 domain binds directly to tyrosine-phosphorylated FAK, and the binding site has been identified as Tyr925 by site directed mutagenesis
- Several transcript variants encoding different isoforms have been found for the FAK gene, but the full-length natures of only three of them have been determined.
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Antigen: FAK
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: P34152, Q05397
Gene Symbols: PTK2
Immunogen: Purified recombinant fragment of human FAK expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 14083, 5747
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: 10H7
Conjugate: Unconjugated
Gene: PTK2
Gene Alias: CG10023; CG10023-PA; CG10023-PB; CG10023-PC; CG10023-PD; CG10023-PF; CG10023-PG; CT28129; DFAK; DFak56; Dmel\CG10023; Dmel_CG10023; DmFAK; EC 2.7.10.2; Fadk; FADK 1; Fak; Fak1; Fak56; fak56D; FAK65D; Fak-PA; Fak-PB; Fak-PC; Fak-PD; Fak-PF; Fak-PG; FAK-related non-kinase polypeptide; focal adhesion kinase; Focal adhesion kinase 1; focal adhesion kinase homolog; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase pp125FAK; focal adhesion kinase-related nonkinase; focal ashension kinase 1; FRNK; I79_019430; Kiaa4203; mKIAA4203; p125FAK; p41/p43FRNK; pFAK; pp125 PTK2; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; protein tyrosine kinase 2; protein tyrosine kinase 2 L homeolog; protein-tyrosine kinase; protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2; ptk2.L; tyrosine kinase; XELAEV_18032408mg; XPFAK
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1
Antigen:
FAK
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
P34152, Q05397
Gene Symbols:
PTK2
Immunogen:
Purified recombinant fragment of human FAK expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
14083, 5747
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
10H7
Conjugate:
Unconjugated
Gene:
PTK2
Gene Alias:
CG10023; CG10023-PA; CG10023-PB; CG10023-PC; CG10023-PD; CG10023-PF; CG10023-PG; CT28129; DFAK; DFak56; Dmel\CG10023; Dmel_CG10023; DmFAK; EC 2.7.10.2; Fadk; FADK 1; Fak; Fak1; Fak56; fak56D; FAK65D; Fak-PA; Fak-PB; Fak-PC; Fak-PD; Fak-PF; Fak-PG; FAK-related non-kinase polypeptide; focal adhesion kinase; Focal adhesion kinase 1; focal adhesion kinase homolog; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase pp125FAK; focal adhesion kinase-related nonkinase; focal ashension kinase 1; FRNK; I79_019430; Kiaa4203; mKIAA4203; p125FAK; p41/p43FRNK; pFAK; pp125 PTK2; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; protein tyrosine kinase 2; protein tyrosine kinase 2 L homeolog; protein-tyrosine kinase; protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2; ptk2.L; tyrosine kinase; XELAEV_18032408mg; XPFAK
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1
Antigen: PP1 alpha
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: P62136, P62137
Gene Symbols: PPP1CA
Immunogen: Purified recombinant fragment of human PPP1A expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 19045, 5499
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Western Blot
Clone: 6D1
Conjugate: Unconjugated
Gene: PPP1CA
Gene Alias: 96A; CG6593; CG6593-PA; CG6593-PB; dism2; Dmel\CG6593; Dmel_CG6593; DmPp1-96A; GADD34; LD14639p; MGC15877; MGC1674; PP1; PP1 96A; PP1 alpha96a; Pp1-96A; PP1A; PP-1A; PP1A-96A; PP1alpha; PP1alpha[[1]]; PP1alpha96A; pp1alpha-96A; Pp1alpha-96A-PA; Pp1alpha-96A-PB; PP1c; PP1c 96A; PPP1A; Ppp1c; Ppp1ca; protein phosphatase 1; protein phosphatase 1 catalytic subunit alpha; protein phosphatase 1, catalytic subunit, alpha isoform; protein phosphatase 1, catalytic subunit, alpha isozyme; Protein phosphatase 1alpha at 96A; protein phosphatase type 1 alpha catalytic subunit; Protein phosphatase type 1 alpha, catalytic subunit; protein phosphatase-1d; serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit; Serine/threonine-protein phosphatase alpha-1 isoform; Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; testicular tissue protein Li 155
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1
Antigen:
PP1 alpha
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
P62136, P62137
Gene Symbols:
PPP1CA
Immunogen:
Purified recombinant fragment of human PPP1A expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
19045, 5499
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Western Blot
Clone:
6D1
Conjugate:
Unconjugated
Gene:
PPP1CA
Gene Alias:
96A; CG6593; CG6593-PA; CG6593-PB; dism2; Dmel\CG6593; Dmel_CG6593; DmPp1-96A; GADD34; LD14639p; MGC15877; MGC1674; PP1; PP1 96A; PP1 alpha96a; Pp1-96A; PP1A; PP-1A; PP1A-96A; PP1alpha; PP1alpha[[1]]; PP1alpha96A; pp1alpha-96A; Pp1alpha-96A-PA; Pp1alpha-96A-PB; PP1c; PP1c 96A; PPP1A; Ppp1c; Ppp1ca; protein phosphatase 1; protein phosphatase 1 catalytic subunit alpha; protein phosphatase 1, catalytic subunit, alpha isoform; protein phosphatase 1, catalytic subunit, alpha isozyme; Protein phosphatase 1alpha at 96A; protein phosphatase type 1 alpha catalytic subunit; Protein phosphatase type 1 alpha, catalytic subunit; protein phosphatase-1d; serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit; Serine/threonine-protein phosphatase alpha-1 isoform; Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; testicular tissue protein Li 155
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1
Antigen: ATP2C1
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: P98194
Gene Symbols: Atp2c1
Immunogen: Purified recombinant fragment of ATP2C1 expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 27032
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunohistochemistry, Western Blot
Clone: 4G12
Conjugate: Unconjugated
Gene: Atp2c1
Gene Alias: 1700121J11Rik; ATP2C1; ATP2C1A; ATPase 2C1; ATPase secretory pathway Ca2+ transporting 1; ATPase, Ca(2+)-sequestering; ATPase, Ca++ transporting, type 2C, member 1; ATPase, Ca++-sequestering; ATP-dependent Ca(2+) pump PMR1; AW061228; BCPM; calcium-transporting ATPase 2C1; calcium-transporting ATPase type 2C member 1; D930003G21Rik; HHD; hSPCA1; HUSSY 28; HUSSY-28; KIAA1347; Pmr1; PMR1L; rat; secretory pathway Ca(2+)-ATPase 1; secretory pathway Ca2+/Mn2+ ATPase 1; SPCA; SPCA1
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG1
Antigen:
ATP2C1
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
P98194
Gene Symbols:
Atp2c1
Immunogen:
Purified recombinant fragment of ATP2C1 expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
27032
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Western Blot
Clone:
4G12
Conjugate:
Unconjugated
Gene:
Atp2c1
Gene Alias:
1700121J11Rik; ATP2C1; ATP2C1A; ATPase 2C1; ATPase secretory pathway Ca2+ transporting 1; ATPase, Ca(2+)-sequestering; ATPase, Ca++ transporting, type 2C, member 1; ATPase, Ca++-sequestering; ATP-dependent Ca(2+) pump PMR1; AW061228; BCPM; calcium-transporting ATPase 2C1; calcium-transporting ATPase type 2C member 1; D930003G21Rik; HHD; hSPCA1; HUSSY 28; HUSSY-28; KIAA1347; Pmr1; PMR1L; rat; secretory pathway Ca(2+)-ATPase 1; secretory pathway Ca2+/Mn2+ ATPase 1; SPCA; SPCA1
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG1
Antigen: AKT2
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: P31751, P47197
Gene Symbols: Akt2
Immunogen: Purified recombinant fragment of human AKT2 expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 208, 25233
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: 1B6
Conjugate: Unconjugated
Gene: Akt2
Gene Alias: 2410016A19Rik; AKT serine/threonine kinase 2; Akt2; AKT2 kinase; AW554154; HIHGHH; murine thymoma viral (v-akt) homolog-2; murine thymoma viral (v-akt) oncogene homolog 2; PKB; PKB beta; PKBB; PKBBETA; PRKBB; protein kinase Akt-2; Protein kinase B beta; protein kinase B, beta; putative v-akt murine thymoma viral oncoprotein 2; rac protein kinase beta; RAC protein kinase beta RAC-PK beta; RAC-BETA; RAC-beta serine/threonine protein kinase; RAC-beta serine/threonine-protein kinase; RAC-PK-beta; thymoma viral proto-oncogene 2; v-akt murine thymoma viral oncogene homolog 2
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG2b
Antigen:
AKT2
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
P31751, P47197
Gene Symbols:
Akt2
Immunogen:
Purified recombinant fragment of human AKT2 expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
208, 25233
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
1B6
Conjugate:
Unconjugated
Gene:
Akt2
Gene Alias:
2410016A19Rik; AKT serine/threonine kinase 2; Akt2; AKT2 kinase; AW554154; HIHGHH; murine thymoma viral (v-akt) homolog-2; murine thymoma viral (v-akt) oncogene homolog 2; PKB; PKB beta; PKBB; PKBBETA; PRKBB; protein kinase Akt-2; Protein kinase B beta; protein kinase B, beta; putative v-akt murine thymoma viral oncoprotein 2; rac protein kinase beta; RAC protein kinase beta RAC-PK beta; RAC-BETA; RAC-beta serine/threonine protein kinase; RAC-beta serine/threonine-protein kinase; RAC-PK-beta; thymoma viral proto-oncogene 2; v-akt murine thymoma viral oncogene homolog 2
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG2b