PIMA515668
Bcl-2 Monoclonal Antibody (8E12), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515668-Each-of-1 | In Stock | ₹ 47,956.38 |
PIMA515668 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,956.38
GST (18%): ₹ 8,632.148
Total Price: ₹ 56,588.528
Antigen
Bcl-2
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
P10415, P10417
Gene Symbols
Bcl2
Immunogen
Synthetic peptide corresponding to residues surrounding BCL-2, conjugated to KLH.
Regulatory Status
RUO
Gene ID (Entrez)
12043, 596
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry
Clone
8E12
Conjugate
Unconjugated
Gene
Bcl2
Gene Alias
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15668 targets BCL-2 in indirect ELISA, FACS, IF, and IHC applications and shows reactivity with Human and mouse samples
- The MA5-15668 immunogen is synthetic peptide corresponding to residues surrounding BCL-2, conjugated to KLH
- MA5-15668 detects BCL-2 which has a predicted molecular weight of approximately 26kDa
- BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
- The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
- Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
- Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
- Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
- Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
- In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
- Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
- The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.
Compare Similar Items
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Antigen: Bcl-2
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: P10415, P10417
Gene Symbols: Bcl2
Immunogen: Synthetic peptide corresponding to residues surrounding BCL-2, conjugated to KLH.
Regulatory Status: RUO
Gene ID (Entrez): 12043, 596
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry
Clone: 8E12
Conjugate: Unconjugated
Gene: Bcl2
Gene Alias: apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1
Antigen:
Bcl-2
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
P10415, P10417
Gene Symbols:
Bcl2
Immunogen:
Synthetic peptide corresponding to residues surrounding BCL-2, conjugated to KLH.
Regulatory Status:
RUO
Gene ID (Entrez):
12043, 596
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry
Clone:
8E12
Conjugate:
Unconjugated
Gene:
Bcl2
Gene Alias:
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1
Antigen: PTK7
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: Q13308
Gene Symbols: Ptk7
Immunogen: Purified recombinant fragment of human PTK7 expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 5754
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunohistochemistry, Western Blot
Clone: 4F9
Conjugate: Unconjugated
Gene: Ptk7
Gene Alias: 8430404F20Rik; CCK4; CCK-4; chz; Colon carcinoma kinase 4; inactive tyrosine-protein kinase 7; mPTK7/CCK4; protein chuzhoi; protein tyrosine kinase 7; protein tyrosine kinase 7 (inactive); protein-tyrosine kinase 7; Pseudo tyrosine kinase receptor 7; Ptk7; PTK7 protein tyrosine kinase 7; receptor tyrosine kinase-like protein; serum response factor; Srf; Tyrosine-protein kinase-like 7
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
PTK7
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
Q13308
Gene Symbols:
Ptk7
Immunogen:
Purified recombinant fragment of human PTK7 expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
5754
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Western Blot
Clone:
4F9
Conjugate:
Unconjugated
Gene:
Ptk7
Gene Alias:
8430404F20Rik; CCK4; CCK-4; chz; Colon carcinoma kinase 4; inactive tyrosine-protein kinase 7; mPTK7/CCK4; protein chuzhoi; protein tyrosine kinase 7; protein tyrosine kinase 7 (inactive); protein-tyrosine kinase 7; Pseudo tyrosine kinase receptor 7; Ptk7; PTK7 protein tyrosine kinase 7; receptor tyrosine kinase-like protein; serum response factor; Srf; Tyrosine-protein kinase-like 7
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: RAB10
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: P61026, P61027
Gene Symbols: RAB10
Immunogen: Purified recombinant fragment of human Rab10 expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 10890, 19325
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunocytochemistry, Western Blot
Clone: 4E2
Conjugate: Unconjugated
Gene: RAB10
Gene Alias: Ac1075; AW107754; GTP-binding protein RAB10; Rab10; RAB10, member RAS oncogene family; ras-related GTP-binding protein; ras-related protein rab10; ras-related protein Rab-10
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1
Antigen:
RAB10
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
P61026, P61027
Gene Symbols:
RAB10
Immunogen:
Purified recombinant fragment of human Rab10 expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
10890, 19325
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Western Blot
Clone:
4E2
Conjugate:
Unconjugated
Gene:
RAB10
Gene Alias:
Ac1075; AW107754; GTP-binding protein RAB10; Rab10; RAB10, member RAS oncogene family; ras-related GTP-binding protein; ras-related protein rab10; ras-related protein Rab-10
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1
Antigen: HAS1
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: Q92839
Gene Symbols: Has1
Immunogen: Purified recombinant fragment of human HAS1 expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 3036
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunocytochemistry, Western Blot
Clone: 3E10
Conjugate: Unconjugated
Gene: Has1
Gene Alias: HA synthase 1; HAS; Has1; huHAS1; Hyaluronan synthase 1; hyaluronan synthase1; hyaluronate synthase 1; Hyaluronic acid synthase 1
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
HAS1
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
Q92839
Gene Symbols:
Has1
Immunogen:
Purified recombinant fragment of human HAS1 expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
3036
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Western Blot
Clone:
3E10
Conjugate:
Unconjugated
Gene:
Has1
Gene Alias:
HA synthase 1; HAS; Has1; huHAS1; Hyaluronan synthase 1; hyaluronan synthase1; hyaluronate synthase 1; Hyaluronic acid synthase 1
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1