PIMA515743

APAF1 Monoclonal Antibody (2E10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515743-Each-of-1 In Stock ₹ 45,304.02

PIMA515743 - Each of 1

₹ 45,304.02

In Stock

Quantity

1

Base Price: ₹ 45,304.02

GST (18%): ₹ 8,154.724

Total Price: ₹ 53,458.744

Antigen

APAF1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

O14727, O88879, Q9EPV5

Gene Symbols

APAF1

Immunogen

A peptide corresponding to amino acids near the carboxy terminus of human Apaf1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry, Western Blot

Clone

2E10

Conjugate

Unconjugated

Gene

APAF1

Gene Alias

6230400I06Rik; APAF1; APAF-1; Apaf1l; apoptotic peptidase activating factor 1; apoptotic protease activating factor 1; apoptotic protease-activating factor 1; CED4; DKFZp781B1145; fog; forebrain overgrowth; KIAA0413; mKIAA0413

Host Species

Mouse

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11783, 317, 78963

Content And Storage

-20°C

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA515744

--

Img

Thermo Scientific

PIMA515765

--

Img

Thermo Scientific

PIMA516085

--

Img

Thermo Scientific

PIMA515778

--

Img

Thermo Scientific

PIMA515783

--

Img

Thermo Scientific

PIMA516184

--

Img

Thermo Scientific

PIMA515010

--

Img

Thermo Scientific

PIMA516173

--

Description

  • In Western blot applications, this antibody detects a band at ∽130kDa
  • A suggested positive control is K562 cell lysate
  • APAF1 gene encodes a cytoplasmic protein that initiates apoptosis
  • This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC)
  • Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome
  • The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form
  • Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis
  • Alternative splicing results in several transcript variants encoding different isoforms.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA515743

--


Antigen:
APAF1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O14727, O88879, Q9EPV5

Gene Symbols:
APAF1

Immunogen:
A peptide corresponding to amino acids near the carboxy terminus of human Apaf1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry, Western Blot

Clone:
2E10

Conjugate:
Unconjugated

Gene:
APAF1

Gene Alias:
6230400I06Rik; APAF1; APAF-1; Apaf1l; apoptotic peptidase activating factor 1; apoptotic protease activating factor 1; apoptotic protease-activating factor 1; CED4; DKFZp781B1145; fog; forebrain overgrowth; KIAA0413; mKIAA0413

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11783, 317, 78963

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515744

--


Antigen:
APAF1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O14727, O88879, Q9EPV5

Gene Symbols:
APAF1

Immunogen:
A peptide corresponding to amino acids near the carboxy terminus of human Apaf1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry

Clone:
5E11

Conjugate:
Unconjugated

Gene:
APAF1

Gene Alias:
6230400I06Rik; APAF1; APAF-1; Apaf1l; apoptotic peptidase activating factor 1; apoptotic protease activating factor 1; apoptotic protease-activating factor 1; CED4; DKFZp781B1145; fog; forebrain overgrowth; KIAA0413; mKIAA0413

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11783, 317, 78963

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515745

--


Antigen:
DC-SIGN

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9NNX6

Gene Symbols:
CD209

Immunogen:
A recombinant His-tagged protein fragment corresponding to the extracellular region of human DC-SIGN.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry, Western Blot

Clone:
5D7

Conjugate:
Unconjugated

Gene:
CD209

Gene Alias:
CD209; CD209 antigen; CD209 antigen-like protein A; CD209 molecule; Cd209a; CD209a antigen; CD209a molecule; Cd209d; CD209d antigen; CDSIGN; Cire; CLEC4L; Clec4m; C-type lectin domain family 4 member L; C-type lectin domain family 4, member L; C-type lectin domain family 4, member M; Dcsign; DC-SIGN; DC-SIGN1; Dc-signr; DC-SIGN-related protein; Dendritic cell-specific ICAM-3-grabbing non-integrin; dendritic cell-specific ICAM-3-grabbing non-integrin 1; dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin; dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin; HIV gpl20-binding protein; MGC129965; MGC130443; RGD1561104; SIGN-R1; SIGNR5

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
30835

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515746

--


Antigen:
DC-SIGN

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9NNX6

Gene Symbols:
CD209

Immunogen:
A recombinant His-tagged protein fragment corresponding to the extracellular region of human DC-SIGN.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry, Western Blot

Clone:
8B6

Conjugate:
Unconjugated

Gene:
CD209

Gene Alias:
CD209; CD209 antigen; CD209 antigen-like protein A; CD209 molecule; Cd209a; CD209a antigen; CD209a molecule; Cd209d; CD209d antigen; CDSIGN; Cire; CLEC4L; Clec4m; C-type lectin domain family 4 member L; C-type lectin domain family 4, member L; C-type lectin domain family 4, member M; Dcsign; DC-SIGN; DC-SIGN1; Dc-signr; DC-SIGN-related protein; Dendritic cell-specific ICAM-3-grabbing non-integrin; dendritic cell-specific ICAM-3-grabbing non-integrin 1; dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin; dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin; HIV gpl20-binding protein; MGC129965; MGC130443; RGD1561104; SIGN-R1; SIGNR5

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
30835

Content And Storage:
-20°C

Form:
Liquid