PIMA515767

XBP1 Monoclonal Antibody (3H1G4), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515767-Each-of-1 In Stock ₹ 48,298.62

PIMA515767 - Each of 1

₹ 48,298.62

In Stock

Quantity

1

Base Price: ₹ 48,298.62

GST (18%): ₹ 8,693.752

Total Price: ₹ 56,992.372

Antigen

XBP1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

O35426, P17861, Q9R1S4

Gene Symbols

Xbp1

Immunogen

Recombinant protein corresponding to amino acids 2 to 160 of human XBP-1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Western Blot

Clone

3H1G4

Conjugate

Unconjugated

Gene

Xbp1

Gene Alias

D11Ertd39e; Hepatocarcinogenesis-related transcription factor; HTF; OTTHUMP00000028682; Tax-responsive element-binding protein 5; tax-responsive element-binding protein 5 homolog; TREB5; TREB-5; X-box binding protein 1; X-box-binding protein 1; X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form; XBP1; XBP-1; XBP2

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

22433, 289754, 7494

Content And Storage

-20°C

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA515768

--

Img

Thermo Scientific

PIMA515626

--

Img

Thermo Scientific

PIMA515314

--

Img

Thermo Scientific

PIMA515912

--

Img

Thermo Scientific

PIMA515272

--

Img

Thermo Scientific

PIMA515032

--

Img

Thermo Scientific

PIMA515312

--

Img

Thermo Scientific

PIMA514948

--

Description

  • A suggested positive control is XBP-1 recombinant protein
  • XBP1 encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box
  • This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter
  • It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator
  • It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1)
  • The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor
  • The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress
  • A pseudogene of XBP1 has been identified and localized to chromosome 5.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA515767

--


Antigen:
XBP1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O35426, P17861, Q9R1S4

Gene Symbols:
Xbp1

Immunogen:
Recombinant protein corresponding to amino acids 2 to 160 of human XBP-1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Western Blot

Clone:
3H1G4

Conjugate:
Unconjugated

Gene:
Xbp1

Gene Alias:
D11Ertd39e; Hepatocarcinogenesis-related transcription factor; HTF; OTTHUMP00000028682; Tax-responsive element-binding protein 5; tax-responsive element-binding protein 5 homolog; TREB5; TREB-5; X-box binding protein 1; X-box-binding protein 1; X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form; XBP1; XBP-1; XBP2

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
22433, 289754, 7494

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515768

--


Antigen:
XBP1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O35426, P17861, Q9R1S4

Gene Symbols:
Xbp1

Immunogen:
Recombinant protein corresponding to amino acids 2 to 160 of human XBP-1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Western Blot

Clone:
9B7E5

Conjugate:
Unconjugated

Gene:
Xbp1

Gene Alias:
D11Ertd39e; Hepatocarcinogenesis-related transcription factor; HTF; OTTHUMP00000028682; Tax-responsive element-binding protein 5; tax-responsive element-binding protein 5 homolog; TREB5; TREB-5; X-box binding protein 1; X-box-binding protein 1; X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form; XBP1; XBP-1; XBP2

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22433, 289754, 7494

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515769

--


Antigen:
HAX1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O00165, O35387, Q7TSE9

Gene Symbols:
Hax1

Immunogen:
A 15 amino acid peptide near the amino terminus of human Hax1a.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
8F9G7

Conjugate:
Unconjugated

Gene:
Hax1

Gene Alias:
FLJ17042; FLJ18492; FLJ93803; Hax1; HAX-1; HCLS1 (and PKD2) associated protein; HCLS1 associated protein X-1; HCLS1 associated X-1; HCLS1-associated protein X-1; HCLSBP1; HS1 binding protein; HS1-associated protein X-1; HS1-associating protein X-1; HS1-binding protein 1; HS1BP1; HSP1BP-1; mHAX-1s; OTTHUMP00000034190; RP11-137P24.1; SCN3; SIG-111; Silg111

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10456, 23897, 291202

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515770

--


Antigen:
HAX1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O00165, Q7TSE9

Gene Symbols:
Hax1

Immunogen:
A 15 amino acid peptide near the amino terminus of human Hax1a.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG3

Applications:
Western Blot

Clone:
9G3D11

Conjugate:
Unconjugated

Gene:
Hax1

Gene Alias:
FLJ17042; FLJ18492; FLJ93803; Hax1; HAX-1; HCLS1 (and PKD2) associated protein; HCLS1 associated protein X-1; HCLS1 associated X-1; HCLS1-associated protein X-1; HCLSBP1; HS1 binding protein; HS1-associated protein X-1; HS1-associating protein X-1; HS1-binding protein 1; HS1BP1; HSP1BP-1; mHAX-1s; OTTHUMP00000034190; RP11-137P24.1; SCN3; SIG-111; Silg111

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10456, 291202

Content And Storage:
-20°C

Form:
Liquid