PIMA515780

PD-1 Monoclonal Antibody (7A11B1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515780-Each-of-1 In Stock ₹ 48,298.62

PIMA515780 - Each of 1

₹ 48,298.62

In Stock

Quantity

1

Base Price: ₹ 48,298.62

GST (18%): ₹ 8,693.752

Total Price: ₹ 56,992.372

Antigen

PD-1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q02242, Q15116

Gene Symbols

Pdcd1

Immunogen

A ∽150 amino acid recombinant protein from near the amino terminus of mouse PD-1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry, Western Blot

Clone

7A11B1

Conjugate

Unconjugated

Gene

Pdcd1

Gene Alias

CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

18566, 301626, 5133

Content And Storage

-20°C

Form

Liquid

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Description

  • A suggested positive control is PD-1 recombinant protein
  • Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC)
  • T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC
  • PD-1 can bind two different but related ligands, PDL-1 and PDL-2
  • Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of &quotedanger signals&quote such as LPS or other molecules associated with bacteria or other pathogens
  • Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases
  • Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE.

Compare Similar Items

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Img

Thermo Scientific

PIMA515780

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Antigen:
PD-1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q02242, Q15116

Gene Symbols:
Pdcd1

Immunogen:
A ∽150 amino acid recombinant protein from near the amino terminus of mouse PD-1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry, Western Blot

Clone:
7A11B1

Conjugate:
Unconjugated

Gene:
Pdcd1

Gene Alias:
CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
18566, 301626, 5133

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515781

--


Antigen:
PD-1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q02242, Q15116

Gene Symbols:
Pdcd1

Immunogen:
A ∽150 amino acid recombinant protein from near the amino terminus of mouse PD-1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
12A7D7

Conjugate:
Unconjugated

Gene:
Pdcd1

Gene Alias:
CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
18566, 301626, 5133

Content And Storage:
4°, C

Form:
Liquid

Img

Thermo Scientific

PIMA515783

--


Antigen:
IRAK1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P51617, Q62406

Gene Symbols:
Irak1

Immunogen:
Recombinant protein corresponding to amino acids 618 - 712 of human IRAK.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry, Western Blot

Clone:
8F1A7

Conjugate:
Unconjugated

Gene:
Irak1

Gene Alias:
AA408924; Il1rak; interleukin 1 receptor associated kinase 1; interleukin-1 receptor-associated kinase 1; interleukin-1 receptor-associated kinase-1; IRAK; Irak1; IRAK-1; IRAK1-S; mPLK; pelle; Pelle homolog; pelle-like protein kinase; Plpk; RGD1563841

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
16179, 363520, 3654

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515784

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Antigen:
Influenza A H1N1 HA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
A synthetic peptide from the Hemagglutinin protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Virus

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Western Blot

Clone:
7H12F6

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
flu hemagglutinin; H1N1 HA; H1N1 hemagglutinin; Influenza H1N1; influenza hemagglutinin

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C

Form:
Liquid