PIMA515861

ASK1 Monoclonal Antibody (2E4), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515861-Each-of-1 In Stock ₹ 47,614.14

PIMA515861 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

ASK1

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

Q99683

Gene Symbols

MAP3K5

Immunogen

Purified recombinant fragment of human MAP3K5 expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

4217

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone

2E4

Conjugate

Unconjugated

Gene

MAP3K5

Gene Alias

7420452D20Rik; apoptosis signal regulating kinase 1; apoptosis signal-regulating kinase 1; ASK; ASK 1; ASK1; ASK-1; EC 2.7.11.25; kinase ASK1; M3K5; MAP/ERK kinase kinase 5; Map3k5; MAPK/ERK kinase kinase 5; MAPKKK5; MEK kinase 5; MEKK 5; Mekk5; mitogen activated protein kinase kinase kinase 5; mitogen-activated protein kinase kinase kinase 5; RGD1306565; RP3-325F22.4

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15861 targets MAP3K5 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human samples
  • The MA5-15861 immunogen is purified recombinant fragment of human MAP3K5 expressed in E
  • Coli
  • MA5-15861 detects MAP3K5 which has a predicted molecular weight of approximately 55kDa
  • MAP3K5 (ASK1) is a serine/threonine kinase that is abundantly expressed in human heart and pancreas and are activated in response to various extracellular stimuli, including cytokines, growth factors and environmental stresses
  • A novel MAP kinase kinase kinase (MAPKKK) was identified and designated ASK1 (for apoptosis signal-regulating kinase 1) and MAPKKK5
  • ASK1 activates two different subgroups of MAPKK, MKK4 and MKK6, which in turn activates c-Jun N-terminal kinase (JNK) and p38 MAP kinase, respectively
  • ASK1/MAPKKK5 is activated by TNFR and Fas through the interaction with members of the TRAF family and Fas-associated protein Daxx
  • Overexpression of ASK1 induced apoptotic cell death and a catalytically inactive form of ASK1 inhibited TNF-a-induced apoptosis
  • ASK1 is expressed in variety of human and mouse tissues.

Compare Similar Items

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Img

Thermo Scientific

PIMA515861

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Antigen:
ASK1

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
Q99683

Gene Symbols:
MAP3K5

Immunogen:
Purified recombinant fragment of human MAP3K5 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
4217

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
2E4

Conjugate:
Unconjugated

Gene:
MAP3K5

Gene Alias:
7420452D20Rik; apoptosis signal regulating kinase 1; apoptosis signal-regulating kinase 1; ASK; ASK 1; ASK1; ASK-1; EC 2.7.11.25; kinase ASK1; M3K5; MAP/ERK kinase kinase 5; Map3k5; MAPK/ERK kinase kinase 5; MAPKKK5; MEK kinase 5; MEKK 5; Mekk5; mitogen activated protein kinase kinase kinase 5; mitogen-activated protein kinase kinase kinase 5; RGD1306565; RP3-325F22.4

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515863

--


Antigen:
HSP90 beta

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P08238, P11499, P34058

Gene Symbols:
Hsp90ab1

Immunogen:
Purified recombinant fragment of human HSP90AB1 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
15516, 301252, 3326

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
5G4D2

Conjugate:
Unconjugated

Gene:
Hsp90ab1

Gene Alias:
90kDa; 90-kDa heat shock protein beta; AL022974; C81438; D6S182; heat shock 84 kDa; heat shock 90 kDa protein; heat shock 90kD protein 1, beta; heat shock 90kDa protein 1, beta; heat shock cognate protein HSP 90-beta; Heat shock protein; heat shock protein 1, beta; heat shock protein 90 alpha (cytosolic), class B member 1; heat shock protein 90 alpha family class B member 1; heat shock protein 90 beta; heat shock protein 90 kDa; heat shock protein 90 kDa alpha class B member 1; heat shock protein 90kDa alpha (cytosolic), class B member 1; heat shock protein 90kDa alpha family class B member 1; Heat shock protein HSP 90-beta; heat shock protein, 84 kDa 1; HSP; HSP 84; HSP 90; Hsp84; Hsp84-1; Hsp90; hsp90 beta; HSP90AB1; HSP90B; HSP90-beta; HSPC2; HSPCB; retinal degeneration slow protein; RP1-302G2.1; TSTA; Tumor-specific transplantation 84 kDa antigen; Unknown (protein for IMAGE:7943063)

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515864

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Antigen:
HSP90 beta

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P08238, P11499, P34058

Gene Symbols:
Hsp90ab1

Immunogen:
Purified recombinant fragment of human HSP90AB1 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
15516, 301252, 3326

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
1D9

Conjugate:
Unconjugated

Gene:
Hsp90ab1

Gene Alias:
90kDa; 90-kDa heat shock protein beta; AL022974; C81438; D6S182; heat shock 84 kDa; heat shock 90 kDa protein; heat shock 90kD protein 1, beta; heat shock 90kDa protein 1, beta; heat shock cognate protein HSP 90-beta; Heat shock protein; heat shock protein 1, beta; heat shock protein 90 alpha (cytosolic), class B member 1; heat shock protein 90 alpha family class B member 1; heat shock protein 90 beta; heat shock protein 90 kDa; heat shock protein 90 kDa alpha class B member 1; heat shock protein 90kDa alpha (cytosolic), class B member 1; heat shock protein 90kDa alpha family class B member 1; Heat shock protein HSP 90-beta; heat shock protein, 84 kDa 1; HSP; HSP 84; HSP 90; Hsp84; Hsp84-1; Hsp90; hsp90 beta; HSP90AB1; HSP90B; HSP90-beta; HSPC2; HSPCB; retinal degeneration slow protein; RP1-302G2.1; TSTA; Tumor-specific transplantation 84 kDa antigen; Unknown (protein for IMAGE:7943063)

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515865

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Antigen:
Fyn

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P06241

Gene Symbols:
Fyn

Immunogen:
Purified recombinant fragment of human FYN expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
2534

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
2A10

Conjugate:
Unconjugated

Gene:
Fyn

Gene Alias:
AI448320; AW552119; C syn protooncogene; c-syn protooncogene; EC 2.7.10.2; Fyn; fyn {ECO:0000312; FYN oncogene related to SRC, FGR, YES; Fyn proto-oncogene; FYN proto-oncogene, Src family tyrosine kinase; kinase Fyn; MGC45350; OKT3-induced calcium influx regulator; OTTHUMP00000017916; OTTHUMP00000017917; P59 p59-Fyn; p59-Fyn; Proto-oncogene c-Fyn; Protooncogene Syn; proto-oncogene Syn; proto-oncogene tyrosine-protein kinase Fyn; RGD:2641}; RP1-66H14.1; SLK; Src Kinase p59; Src like kinase; src/yes-related novel; src-like kinase; SYN; tyrosine kinase p59fyn(T); tyrosine-protein kinase Fyn

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1