PIMA516124
SREBP1 Monoclonal Antibody (2A4), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516124-Each-of-1 | In Stock | ₹ 41,967.18 |
PIMA516124 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,967.18
GST (18%): ₹ 7,554.092
Total Price: ₹ 49,521.272
Antigen
SREBP1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P36956, P56720, Q60416, Q9WTN3
Gene Symbols
SREBF1
Immunogen
6 His-tag fusion protein of SREBP1 corresponding to amino acids 301-407
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Canine, Chicken, Hamster, Human, Mouse, Rat
Form
Liquid
Applications
Western Blot
Clone
2A4
Conjugate
Unconjugated
Gene
SREBF1
Gene Alias
ADD1; ADD-1; Adipocyte determination- and differentiation-dependent factor 1; bHLHd1; Class D basic helix-loop-helix protein 1; D630008H06; I79_010155; nt-SREBP1; Processed sterol regulatory element-binding protein 1; SREBF1; SREBP1; SREBP-1; SREBP1a; SREBP-1a; SREBP1c; SREBP-1c; sterol regulatory element binding protein 1; sterol regulatory element binding protein-1; sterol regulatory element binding transcription factor 1; sterol regulatory element binding-protein 1; sterol regulatory element-binding protein 1; Sterol regulatory element-binding transcription factor 1
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
100689018, 20787, 373915, 403475, 6720, 78968
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1 κ
Related Products
Description
- In Western blot, a band can be seen at 125 kDa (precursor) and additional bands may be seen at 60-70 kDa (cleaved)
- Suggested positive control: IMR 5 and HeLa cells.
- Sterol regulatory element-binding proteins (SREBPs) are transcription factors that are members of the basic helix-loop-helix leucine zipper family of DNA binding proteins
- Three isoforms have been identified in mammalian tissues that vary in structure, regulation, and function
- SREBP-1a and SREBP-1c (originally cloned as ADD1) are protein products of alternative promoter usage of the SREBP-1 gene
- The third isoform is transcribed from a different gene, SREBP-2
- SREBPs are present as 120 kDa inactive precursors in the endoplasmic reticulum (ER) membrane
- Upon activation, the SREBP protein is translocated to the Golgi and proteolytic cleavage occurs resulting in a mature transcriptionally active 60-78 kDa fragment
- In liver and adipose tissues, SREBPs have a significant influence on lipid and cholesterol accumulation by inducing the transcription of genes involved in these processes
- While SREBP-1 is thought to be more important in regulating the expression of genes involved in triglyceride synthesis and accumulation, SREBP-2 has been more closely linked to those involved in cholesterol synthesis and accumulation.
Compare Similar Items
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Antigen: SREBP1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: P36956, P56720, Q60416, Q9WTN3
Gene Symbols: SREBF1
Immunogen: 6 His-tag fusion protein of SREBP1 corresponding to amino acids 301-407
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Canine, Chicken, Hamster, Human, Mouse, Rat
Form: Liquid
Applications: Western Blot
Clone: 2A4
Conjugate: Unconjugated
Gene: SREBF1
Gene Alias: ADD1; ADD-1; Adipocyte determination- and differentiation-dependent factor 1; bHLHd1; Class D basic helix-loop-helix protein 1; D630008H06; I79_010155; nt-SREBP1; Processed sterol regulatory element-binding protein 1; SREBF1; SREBP1; SREBP-1; SREBP1a; SREBP-1a; SREBP1c; SREBP-1c; sterol regulatory element binding protein 1; sterol regulatory element binding protein-1; sterol regulatory element binding transcription factor 1; sterol regulatory element binding-protein 1; sterol regulatory element-binding protein 1; Sterol regulatory element-binding transcription factor 1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100689018, 20787, 373915, 403475, 6720, 78968
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1 κ
Antigen:
SREBP1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
P36956, P56720, Q60416, Q9WTN3
Gene Symbols:
SREBF1
Immunogen:
6 His-tag fusion protein of SREBP1 corresponding to amino acids 301-407
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Chicken, Hamster, Human, Mouse, Rat
Form:
Liquid
Applications:
Western Blot
Clone:
2A4
Conjugate:
Unconjugated
Gene:
SREBF1
Gene Alias:
ADD1; ADD-1; Adipocyte determination- and differentiation-dependent factor 1; bHLHd1; Class D basic helix-loop-helix protein 1; D630008H06; I79_010155; nt-SREBP1; Processed sterol regulatory element-binding protein 1; SREBF1; SREBP1; SREBP-1; SREBP1a; SREBP-1a; SREBP1c; SREBP-1c; sterol regulatory element binding protein 1; sterol regulatory element binding protein-1; sterol regulatory element binding transcription factor 1; sterol regulatory element binding-protein 1; sterol regulatory element-binding protein 1; Sterol regulatory element-binding transcription factor 1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100689018, 20787, 373915, 403475, 6720, 78968
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG1 κ
Antigen: HPi1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: tissue culture supernatant with 0.09% sodium azide
Gene Accession No.: __
Gene Symbols: __
Immunogen: Human pancreatic enriched islet cells containing low levels of exocrine and ductal cells.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen)
Clone: HIC0-4F9
Conjugate: Unconjugated
Gene: __
Gene Alias: Pancreas Marker HPi1
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C, do not freeze
Isotype: IgG1
Antigen:
HPi1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
tissue culture supernatant with 0.09% sodium azide
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Human pancreatic enriched islet cells containing low levels of exocrine and ductal cells.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen)
Clone:
HIC0-4F9
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
Pancreas Marker HPi1
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C, do not freeze
Isotype:
IgG1
Antigen: HPi2
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: tissue culture supernatant with 0.09% sodium azide
Gene Accession No.: __
Gene Symbols: __
Immunogen: Human pancreatic enriched islet cells containing low levels of exocrine and ductal cells.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen)
Clone: HIC1-2B4.2B
Conjugate: Unconjugated
Gene: __
Gene Alias: Pancreas Marker HPi2
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C, do not freeze
Isotype: IgG1
Antigen:
HPi2
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
tissue culture supernatant with 0.09% sodium azide
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Human pancreatic enriched islet cells containing low levels of exocrine and ductal cells.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen)
Clone:
HIC1-2B4.2B
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
Pancreas Marker HPi2
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C, do not freeze
Isotype:
IgG1
Antigen: HPi3
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: tissue culture supernatant with 0.09% sodium azide
Gene Accession No.: __
Gene Symbols: __
Immunogen: Human pancreatic enriched islet cells containing low levels of exocrine and ductal cells.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen)
Clone: HIC1-7H10
Conjugate: Unconjugated
Gene: __
Gene Alias: Pancreas Marker HPi3
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C, do not freeze
Isotype: IgG1
Antigen:
HPi3
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
tissue culture supernatant with 0.09% sodium azide
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Human pancreatic enriched islet cells containing low levels of exocrine and ductal cells.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen)
Clone:
HIC1-7H10
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
Pancreas Marker HPi3
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C, do not freeze
Isotype:
IgG1