PIMA516226

FOXP3 Monoclonal Antibody (16J4G6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA516226-Each-of-1 In Stock ₹ 45,218.46

PIMA516226 - Each of 1

₹ 45,218.46

In Stock

Quantity

1

Base Price: ₹ 45,218.46

GST (18%): ₹ 8,139.323

Total Price: ₹ 53,357.783

Antigen

FOXP3

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

Q9BZS1

Gene Symbols

Foxp3

Immunogen

synthetic peptide corresponding to the exon 2 deletion site was used to immunize mice.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgM

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

16J4G6

Conjugate

Unconjugated

Gene

Foxp3

Gene Alias

AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID

Host Species

Mouse

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

50943

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis
  • FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells
  • FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells
  • Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice
  • In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as X-linked autoimmunity-allergic dysregulation (XLAAD) syndrome
  • Transcript variants of FOXP3 encoding different isoforms have been identified
  • In human breast and colon cancer cells, expression of FOXP3 is regulated by p53 in response to the DNA damage.

Compare Similar Items

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Img

Thermo Scientific

PIMA516226

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Antigen:
FOXP3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q9BZS1

Gene Symbols:
Foxp3

Immunogen:
synthetic peptide corresponding to the exon 2 deletion site was used to immunize mice.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgM

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
16J4G6

Conjugate:
Unconjugated

Gene:
Foxp3

Gene Alias:
AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID

Host Species:
Mouse

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
50943

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA516227

--


Antigen:
ROR gamma

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P51449, P51450

Gene Symbols:
RORC

Immunogen:
A portion of amino acids 1-50 of human ROR gamma

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Western Blot

Clone:
4G419

Conjugate:
Unconjugated

Gene:
RORC

Gene Alias:
IMD42; Nr1f3; Nuclear receptor ROR-gamma; nuclear receptor RZR-gamma; Nuclear receptor subfamily 1 group F member 3; RAR related orphan receptor C; RAR-related orphan nuclear receptor variant 2; RAR-related orphan receptor C; RAR-related orphan receptor C, isoform a; RAR-related orphan receptor gamma; retinoic acid-binding receptor gamma; retinoid-related orphan receptor gamma; retinoid-related orphan receptor-gamma; RORC; RORG; RORgamma; RZRG; RZR-GAMMA; Thor; Thymus orphan receptor; TOR

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
19885, 368158, 6097

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA516228

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Antigen:
IL-17F

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q96PD4

Gene Symbols:
IL17F

Immunogen:
full-length recombinant IL17F

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
4H450

Conjugate:
Unconjugated

Gene:
IL17F

Gene Alias:
C87042; CANDF6; cytokine ML-1; IL17F; IL-17F; IL-24; ILN; Interleukin; interleukin 17F; Interleukin17F; interleukin-17F; interleukin-24; ML1; ML-1; mutant IL-17F

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
112744

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA516229

--


Antigen:
IL-17F

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q96PD4

Gene Symbols:
IL17F

Immunogen:
full-length recombinant IL17F

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
4H1629

Conjugate:
Unconjugated

Gene:
IL17F

Gene Alias:
C87042; CANDF6; cytokine ML-1; IL17F; IL-17F; IL-24; ILN; Interleukin; interleukin 17F; Interleukin17F; interleukin-17F; interleukin-24; ML1; ML-1; mutant IL-17F

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
112744

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid