PIMA516255
EBI3 Monoclonal Antibody (10J706), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516255-Each-of-1 | In Stock | ₹ 45,218.46 |
PIMA516255 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,218.46
GST (18%): ₹ 8,139.323
Total Price: ₹ 53,357.783
Antigen
EBI3
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
O35228
Gene Symbols
EBI3
Immunogen
full length recombinant mouse EBI3
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2b κ
Applications
Flow Cytometry, Western Blot
Clone
10J706
Conjugate
Unconjugated
Gene
EBI3
Gene Alias
cytokine receptor; EBI3; EBI-3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor); epstein-Barr virus-induced gene 3 protein; Epstein-Barr virus-induced gene 3 protein homolog; IL-27; IL27 subunit; IL-27 subunit beta; IL27B; IL-27B; IL35 subunit; interleukin-27 subunit beta
Host Species
Rat
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
50498
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- EBI3 (Epstein-Barr virus Induced-3) is a secreted glycoprotein of the hematopoietin receptor family
- It plays a critical regulatory role in the induction of Th2-type immune responses and the development of Th2-mediated tissue inflammation in vivo, which may be mediated through the control of iNKT cell function
- EBI3 dimerizes with p28 and p35 subunits of IL-12 to form new proteins IL-27 and IL-35, respectively
- IL-27 is an early product of activated antigen presenting cell that is produced upon TLR ligation
- It negatively regulates Th17 cell differentiation
- EBI3 is widely expressed and its expression in dendritic cell is transcriptionally regulated by TLR signaling via MyD88 and NF-kappaB during innate immune responses preceding cytokine driven Th cell development
- EBI3 signal inhibits delayed-type hypersensitivity responses by suppressing IL-17 production and inducing IL-10 hyperproduction
- EBI3 may play a novel role in controlling tumor metastasis via lung CD8+ T cells, and its deficiency is associated with a diminished production of Th2 cytokines which are known to regulate allergic airway inflammation in asthma
- Targeted deletion of EBI3 protects mice from lung metastasis.
Compare Similar Items
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Antigen: EBI3
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: O35228
Gene Symbols: EBI3
Immunogen: full length recombinant mouse EBI3
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Applications: Flow Cytometry, Western Blot
Clone: 10J706
Conjugate: Unconjugated
Gene: EBI3
Gene Alias: cytokine receptor; EBI3; EBI-3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor); epstein-Barr virus-induced gene 3 protein; Epstein-Barr virus-induced gene 3 protein homolog; IL-27; IL27 subunit; IL-27 subunit beta; IL27B; IL-27B; IL35 subunit; interleukin-27 subunit beta
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 50498
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
EBI3
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
O35228
Gene Symbols:
EBI3
Immunogen:
full length recombinant mouse EBI3
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Applications:
Flow Cytometry, Western Blot
Clone:
10J706
Conjugate:
Unconjugated
Gene:
EBI3
Gene Alias:
cytokine receptor; EBI3; EBI-3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor); epstein-Barr virus-induced gene 3 protein; Epstein-Barr virus-induced gene 3 protein homolog; IL-27; IL27 subunit; IL-27 subunit beta; IL27B; IL-27B; IL35 subunit; interleukin-27 subunit beta
Host Species:
Rat
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
50498
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: TLR10
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.05% BSA and 0.05% sodium azide
Gene Accession No.: Q9BXR5
Gene Symbols: TLR10
Immunogen: transfection of 20-474 of TLR10 + 133-200 of hagfish VLRB.61 + human FC into 293F cells
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 3C10C5
Conjugate: Unconjugated
Gene: TLR10
Gene Alias: CD290; MGC104967; MGC126398; MGC126399; TLR10; toll like receptor 10; toll-like receptor 10; UNQ315/PRO358
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 81793
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
TLR10
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.05% BSA and 0.05% sodium azide
Gene Accession No.:
Q9BXR5
Gene Symbols:
TLR10
Immunogen:
transfection of 20-474 of TLR10 + 133-200 of hagfish VLRB.61 + human FC into 293F cells
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
3C10C5
Conjugate:
Unconjugated
Gene:
TLR10
Gene Alias:
CD290; MGC104967; MGC126398; MGC126399; TLR10; toll like receptor 10; toll-like receptor 10; UNQ315/PRO358
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
81793
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: AIM2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: O14862
Gene Symbols: AIM2
Immunogen: Recombinant AIM2
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a κ
Applications: Western Blot
Clone: 10M2B3
Conjugate: Unconjugated
Gene: AIM2
Gene Alias: Absent in melanoma 2; AIM2; Gm1313; Ifi210; ifi-210; Interferon-inducible protein 210; interferon-inducible protein AIM2; Interferon-inducible protein p210; PYHIN4; RP11-520H16.3
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 9447
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
AIM2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
O14862
Gene Symbols:
AIM2
Immunogen:
Recombinant AIM2
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a κ
Applications:
Western Blot
Clone:
10M2B3
Conjugate:
Unconjugated
Gene:
AIM2
Gene Alias:
Absent in melanoma 2; AIM2; Gm1313; Ifi210; ifi-210; Interferon-inducible protein 210; interferon-inducible protein AIM2; Interferon-inducible protein p210; PYHIN4; RP11-520H16.3
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
9447
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: TLR2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q9QUN7
Gene Symbols: Tlr2
Immunogen: A portion of amino acids 400-450 of murine TLR2
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Applications: Flow Cytometry, Immunocytochemistry, Western Blot
Clone: 11G5
Conjugate: Unconjugated
Gene: Tlr2
Gene Alias: CD282; Ly105; TIL4; Tlr2; TLR-2; toll like receptor 2; toll/interleukin-1 receptor-like protein 4; Toll-like receptor; toll-like receptor 2; toll-like receptor 2 variant 1; toll-like receptor 2 variant 2; toll-like-receptor 2, exon 1a_; Toll-like-receptor, exon 1b; Toll-like-receptor, exon 1b_; Toll-like-receptor2, exon 1a
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 24088
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
TLR2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q9QUN7
Gene Symbols:
Tlr2
Immunogen:
A portion of amino acids 400-450 of murine TLR2
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Applications:
Flow Cytometry, Immunocytochemistry, Western Blot
Clone:
11G5
Conjugate:
Unconjugated
Gene:
Tlr2
Gene Alias:
CD282; Ly105; TIL4; Tlr2; TLR-2; toll like receptor 2; toll/interleukin-1 receptor-like protein 4; Toll-like receptor; toll-like receptor 2; toll-like receptor 2 variant 1; toll-like receptor 2 variant 2; toll-like-receptor 2, exon 1a_; Toll-like-receptor, exon 1b; Toll-like-receptor, exon 1b_; Toll-like-receptor2, exon 1a
Host Species:
Rat
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
24088
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid