PIMA516273
TLR3 Monoclonal Antibody (27N3D4), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516273-Each-of-1 | In Stock | ₹ 45,218.46 |
PIMA516273 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,218.46
GST (18%): ₹ 8,139.323
Total Price: ₹ 53,357.783
Antigen
TLR3
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
O15455, Q99MB1
Gene Symbols
TLR3
Immunogen
A portion of amino acids 350-375 of mouse TLR3
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2b κ
Applications
Flow Cytometry, Western Blot
Clone
27N3D4
Conjugate
Unconjugated
Gene
TLR3
Gene Alias
AI957183; CD283; IIAE2; TLR 3; TLR3; TLR-3; toll like receptor 3; toll-like receptor 3; toll-like receptor 3 variant 1
Host Species
Rat
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
142980, 7098
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- TLR3 (Toll-like receptor 3, CD283) is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity
- TLRs are highly conserved from drosophila to humans and share structural and functional similarities
- TLRs recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
- The various TLRs exhibit different patterns of expression
- TLR3 is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes
- TLR3 recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons
- Further, TLR3 may play a role in host defense against viruses, and the use of alternative polyadenylation sites to generate different length transcripts has been noted for the TLR3 gene
- Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans
- The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition
- TLRs characterized so far activate the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway
- TLR3 is the only human TLR which does not utilize MyD88 as an adaptor molecule instead utilizing TRIF in a signaling path which results in downstream activation of IRF-3 and NF-kB
- TLR3 activation leads not only to Type I interferon induction but also to other inflammatory cytokines which result in DC maturation
- TLR3 is known to recognize viral double-stranded (ds) RNA, a molecular pattern associated with viral infection
- Recently it has been shown to recognize viruses such as Influenza A and West Nile Virus and can mediate entry of at least West Nile Virus.
Compare Similar Items
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Antigen: TLR3
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: O15455, Q99MB1
Gene Symbols: TLR3
Immunogen: A portion of amino acids 350-375 of mouse TLR3
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2b κ
Applications: Flow Cytometry, Western Blot
Clone: 27N3D4
Conjugate: Unconjugated
Gene: TLR3
Gene Alias: AI957183; CD283; IIAE2; TLR 3; TLR3; TLR-3; toll like receptor 3; toll-like receptor 3; toll-like receptor 3 variant 1
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 142980, 7098
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
TLR3
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
O15455, Q99MB1
Gene Symbols:
TLR3
Immunogen:
A portion of amino acids 350-375 of mouse TLR3
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Applications:
Flow Cytometry, Western Blot
Clone:
27N3D4
Conjugate:
Unconjugated
Gene:
TLR3
Gene Alias:
AI957183; CD283; IIAE2; TLR 3; TLR3; TLR-3; toll like receptor 3; toll-like receptor 3; toll-like receptor 3 variant 1
Host Species:
Rat
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
142980, 7098
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: NLRP3
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q8R4B8
Gene Symbols: NLRP3
Immunogen: Recombinant mNLRP3 NOD domain protein (AA 216-385).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Applications: Western Blot
Clone: 25N10E9
Conjugate: Unconjugated
Gene: NLRP3
Gene Alias: AGTAVPRL; AII; AII/AVP; Angiotensin/vasopressin receptor AII/AVP-like; AVP; C1orf7; caterpiller protein 1.1; Cias1; CLR1.1; cold autoinflammatory syndrome 1 homolog; cold autoinflammatory syndrome 1 protein; cold autoinflammatory syndrome 1 protein homolog; Cold-induced autoinflammatory syndrome 1 protein; cryopyrin; FCAS; FCAS1; FCU; FLJ95925; mast cell maturation inducible protein 1; mast cell maturation-associated-inducible protein 1; Mmig1; MWS; NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3; NACHT, LRR and PYD containing protein 3; NACHT, LRR and PYD domains-containing protein 3; NACHT/LRR/pyrin domain-containing protein 3; NALP3; NLR family pyrin domain containing 3; NLR family, pyrin domain containing 3; Nlrp3; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3; PYPAF1; PYRIN-containing APAF1-like protein 1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 216799
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
NLRP3
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q8R4B8
Gene Symbols:
NLRP3
Immunogen:
Recombinant mNLRP3 NOD domain protein (AA 216-385).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Applications:
Western Blot
Clone:
25N10E9
Conjugate:
Unconjugated
Gene:
NLRP3
Gene Alias:
AGTAVPRL; AII; AII/AVP; Angiotensin/vasopressin receptor AII/AVP-like; AVP; C1orf7; caterpiller protein 1.1; Cias1; CLR1.1; cold autoinflammatory syndrome 1 homolog; cold autoinflammatory syndrome 1 protein; cold autoinflammatory syndrome 1 protein homolog; Cold-induced autoinflammatory syndrome 1 protein; cryopyrin; FCAS; FCAS1; FCU; FLJ95925; mast cell maturation inducible protein 1; mast cell maturation-associated-inducible protein 1; Mmig1; MWS; NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3; NACHT, LRR and PYD containing protein 3; NACHT, LRR and PYD domains-containing protein 3; NACHT/LRR/pyrin domain-containing protein 3; NALP3; NLR family pyrin domain containing 3; NLR family, pyrin domain containing 3; Nlrp3; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3; PYPAF1; PYRIN-containing APAF1-like protein 1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
216799
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Parainfluenza Virus Type 3 HA
Classification: Monoclonal
Concentration: 5.89 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.5
Gene Accession No.: __
Gene Symbols: __
Immunogen: Parainfluenza 3 haemagglutinin protein
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Virus
Product Type: Antibody
Isotype: IgG2a
Applications: Immunocytochemistry
Clone: PAR3 (341/7H)
Conjugate: Unconjugated
Gene: __
Gene Alias: canine parainfluenza virus; flu hemagglutinin; hPIV-3; HPIV3gp7; influenza hemagglutinin; PIV-3; PIV-3 hemagglutinin
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C
Form: Liquid
Antigen:
Parainfluenza Virus Type 3 HA
Classification:
Monoclonal
Concentration:
5.89 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.5
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Parainfluenza 3 haemagglutinin protein
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunocytochemistry
Clone:
PAR3 (341/7H)
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
canine parainfluenza virus; flu hemagglutinin; hPIV-3; HPIV3gp7; influenza hemagglutinin; PIV-3; PIV-3 hemagglutinin
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C
Form:
Liquid
Antigen: Parainfluenza Virus Type 2 HA
Classification: Monoclonal
Concentration: 7.14 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.5
Gene Accession No.: __
Gene Symbols: __
Immunogen: Parainfluenza 2 haemagglutinin protein
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Virus
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry
Clone: PAR2 (231/9F)
Conjugate: Unconjugated
Gene: __
Gene Alias: canine parainfluenza virus; flu hemagglutinin; hemagglutinin-Neuraminidase; hPIV-2; HPIV2gp7; human parainfluenza virus type 2; influenza hemagglutinin; PIV2 HA; PIV-2 hemagglutinin
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C
Form: Liquid
Antigen:
Parainfluenza Virus Type 2 HA
Classification:
Monoclonal
Concentration:
7.14 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.5
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Parainfluenza 2 haemagglutinin protein
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry
Clone:
PAR2 (231/9F)
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
canine parainfluenza virus; flu hemagglutinin; hemagglutinin-Neuraminidase; hPIV-2; HPIV2gp7; human parainfluenza virus type 2; influenza hemagglutinin; PIV2 HA; PIV-2 hemagglutinin
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C
Form:
Liquid