PIMA516405

Thymidylate Synthase Monoclonal Antibody (SP112), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA516405-Each-of-1 In Stock ₹ 59,720.88

PIMA516405 - Each of 1

₹ 59,720.88

In Stock

Quantity

1

Base Price: ₹ 59,720.88

GST (18%): ₹ 10,749.758

Total Price: ₹ 70,470.638

Antigen

Thymidylate Synthase

Classification

Monoclonal

Concentration

0.113 mg/mL

Formulation

PBS with 1% BSA and 0.1% sodium azide; pH 7.2

Gene Accession No.

P04818

Gene Symbols

TYMS

Immunogen

Synthetic peptide near C-terminus of human TS.

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunohistochemistry (Paraffin)

Clone

SP112

Conjugate

Unconjugated

Gene

TYMS

Gene Alias

HST422; MGC88736; OK/SW-cl.29; Thymidylate synthase; thymidylate synthetase; TMS; TS; Tsase; Tyms; tysy

Host Species

Rabbit

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

7298

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Heat-mediated antigen retrieval is recommended prior to staining, using an EDTA buffer for 10 minutes followed by cooling at room temperature for 20 min
  • Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature
  • A suggested positive control is colon carcinoma or tonsil tissue
  • Thymidylate Synthase (TS) converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis
  • TS is a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors
  • Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate
  • Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.

Compare Similar Items

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Thermo Scientific

PIMA516405

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Antigen:
Thymidylate Synthase

Classification:
Monoclonal

Concentration:
0.113 mg/mL

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2

Gene Accession No.:
P04818

Gene Symbols:
TYMS

Immunogen:
Synthetic peptide near C-terminus of human TS.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin)

Clone:
SP112

Conjugate:
Unconjugated

Gene:
TYMS

Gene Alias:
HST422; MGC88736; OK/SW-cl.29; Thymidylate synthase; thymidylate synthetase; TMS; TS; Tsase; Tyms; tysy

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
7298

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA516407

--


Antigen:
UPK3A

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.6

Gene Accession No.:
O75631

Gene Symbols:
Upk3a

Immunogen:
Synthetic peptide corresponding to C-terminus of human uroplakin III protein.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin)

Clone:
SP73

Conjugate:
Unconjugated

Gene:
Upk3a

Gene Alias:
1110017C07Rik; proplakin IIIa; UP3a; UPIII; UPIIIA; Upk3; UPK3A; uroplakin 3; uroplakin 3A; uroplakin III; Uroplakin-3a

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
7380

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA516408

--


Antigen:
Villin

Classification:
Monoclonal

Concentration:
0.108 mg/mL

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.6

Gene Accession No.:
P09327, Q62468

Gene Symbols:
VIL1

Immunogen:
Synthetic peptide derived from the C-terminus of human villin protein.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
SP145

Conjugate:
Unconjugated

Gene:
VIL1

Gene Alias:
D2S1471; OTTHUMP00000207159; Vil; Vil1; villin 1; villin-1

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
22349, 7429

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

PIMA516409

--


Antigen:
Vimentin

Classification:
Monoclonal

Concentration:
0.006 mg/mL

Formulation:
98.9% PBS with 1% BSA and 0.1% sodium azide; pH 7.20

Gene Accession No.:
P08670

Gene Symbols:
Vim

Immunogen:
Recombinant human vimentin protein.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
SP20

Conjugate:
Unconjugated

Gene:
Vim

Gene Alias:
cb28; class-III intermediate microfilament; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; VIM; VIME; Vimentin; vimentin C-terminus

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7431

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid