PIMA516424

Vinculin Monoclonal Antibody (SP117), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA516424-Each-of-1 In Stock ₹ 47,956.38

PIMA516424 - Each of 1

₹ 47,956.38

In Stock

Quantity

1

Base Price: ₹ 47,956.38

GST (18%): ₹ 8,632.148

Total Price: ₹ 56,588.528

Antigen

Vinculin

Classification

Monoclonal

Conjugate

Unconjugated

Gene

VCL

Gene Alias

9430097D22; AA571387; AI462105; AW545629; CMD1W; CMH15; epididymis luminal protein 114; HEL114; metavinculin; meta-vinculin; metavinculin {ECO:0000250; MV; MVCL; RP11-178G16.3; UniProtKB:P18206}; unnamed protein product; Vcl; vcl {ECO:0000250; VIN; vinc; vinc 1; VINC1; Vinculin; vinculin {ECO:0000250

Host Species

Rabbit

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

7414

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Clone

SP117

Formulation

PBS with 1% BSA and <0.1% sodium azide; pH 7.6

Gene Accession No.

P18206

Gene Symbols

VCL

Immunogen

Synthetic peptide derived from C-terminus of human vinculin protein.

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIMA516409

--

Img

Thermo Scientific

PIMA516408

--

Img

Thermo Scientific

PIMA516407

--

Img

Thermo Scientific

PIMA516415

--

Img

Thermo Scientific

PIMA516421

--

Img

Thermo Scientific

PIMA515421

--

Img

Thermo Scientific

PIMA516333

--

Img

Thermo Scientific

PIMA515395

--

Description

  • Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min
  • Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature
  • A suggested positive control is heart or small intestine tissue
  • Vinculin (VCL) is a cytoskeletal protein associated with cell-cell and cell-extracellular matrix adherens-type junctions
  • It functions as one of several interacting proteins involved in anchoring F-actin to the membrane
  • It has been shown that a sequence of molecular interactions might be involved in the transmembrane assembly of adhesion plaques
  • In the assembly of adhesion plaques, the beta subunit of integrin binds to talin
  • Talin binds to vinculin that interacts with alpha-actinin and possibly with itself
  • Since alpha-actinin binds to and cross-links actin filaments, vinculin represents a key element in the transmembrane linkage of the extracellular matrix to the cytoplasmic microfilament system
  • Mutations in the gene can result in cardiomyopathy dilated 1W or familial hypertrophic 15.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA516424

--


Antigen:
Vinculin

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
VCL

Gene Alias:
9430097D22; AA571387; AI462105; AW545629; CMD1W; CMH15; epididymis luminal protein 114; HEL114; metavinculin; meta-vinculin; metavinculin {ECO:0000250; MV; MVCL; RP11-178G16.3; UniProtKB:P18206}; unnamed protein product; Vcl; vcl {ECO:0000250; VIN; vinc; vinc 1; VINC1; Vinculin; vinculin {ECO:0000250

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
7414

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
SP117

Formulation:
PBS with 1% BSA and <0.1% sodium azide; pH 7.6

Gene Accession No.:
P18206

Gene Symbols:
VCL

Immunogen:
Synthetic peptide derived from C-terminus of human vinculin protein.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIMA516429

--


Antigen:
VCAM-1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
VCAM1

Gene Alias:
adhesion molecule VCAM-1; CD106; CD106 antigen; DKFZp779G2333; INCAM100; INCAM-100; MGC99561; sCD106; soluble CD106; soluble VCAM 1; sVCAM 1; vascular cell adhesion molecule; vascular cell adhesion molecule 1; vascular cell adhesion molecule-1; vascular cell adhesion protein 1; V-CAM 1; Vcam1; Vcam-1; VCAM1B

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
396925, 712036, 7412

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone:
1.G11B1

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P19320

Gene Symbols:
VCAM1

Immunogen:
human endothelial cells

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human, Porcine, Rhesus Monkey

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA516430

--


Antigen:
VCAM-1

Classification:
Monoclonal

Conjugate:
FITC

Gene:
VCAM1

Gene Alias:
adhesion molecule VCAM-1; CD106; CD106 antigen; DKFZp779G2333; INCAM100; INCAM-100; MGC99561; sCD106; soluble CD106; soluble VCAM 1; sVCAM 1; vascular cell adhesion molecule; vascular cell adhesion molecule 1; vascular cell adhesion molecule-1; vascular cell adhesion protein 1; V-CAM 1; Vcam1; Vcam-1; VCAM1B

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
396925, 712036, 7412

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form:
Liquid

Applications:
Flow Cytometry

Clone:
1.G11B1

Formulation:
PBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
P19320

Gene Symbols:
VCAM1

Immunogen:
human endothelial cells

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Porcine, Rhesus Monkey

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA516433

--


Antigen:
CD64

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
FCGR1A

Gene Alias:
AI323638; AV092959; CD64; CD64 antigen; CD64A; Fc fragment of IgG high affinity Ib receptor; Fc fragment of IgG receptor Ia; Fc fragment of IgG, high affinity Ia, receptor (CD64); Fc fragment of IgG, high affinity Ia, receptor for (CD64); Fc fragment of IgG, high affinity Ib, receptor for (CD64); Fc gamma receptor; Fc gamma receptor Ia; Fc receptor, IgG, high affinity I; Fcg1; Fc-gamma receptor 1; Fc-gamma receptor I A1; Fc-gamma RI; Fc-gamma RIA; FcgammaRI; FcgammaRIa; Fcgr1; FCGR1A; Fcgr1b; FcgRI; FCRI; FLJ18345; high affinity IgG Fc receptor, subunit beta; high affinity immunoglobulin gamma Fc receptor I; high-affinity immunoglobulin gamma Fc receptor I; IGFR1; IgG Fc receptor I; IgG high affinity Fc receptor; IGGHAFC; RP11-196G18.2

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2209

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Immunocytochemistry

Clone:
10.1

Formulation:
PBS with no preservative

Gene Accession No.:
P12314

Gene Symbols:
FCGR1A

Immunogen:
Human monocytes

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1