PIMA516478

Dectin 1 (soluble) Monoclonal Antibody (2A11), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA516478-Each-of-1 In Stock ₹ 82,864.86

PIMA516478 - Each of 1

₹ 82,864.86

In Stock

Quantity

1

Base Price: ₹ 82,864.86

GST (18%): ₹ 14,915.675

Total Price: ₹ 97,780.535

Antigen

Dectin 1 (soluble)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

Q6QLQ4

Gene Symbols

Clec7a

Immunogen

Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2b

Applications

Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation

Clone

2A11

Conjugate

Unconjugated

Gene

Clec7a

Gene Alias

Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082

Host Species

Rat

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

56644

Content And Storage

4° C, do not freeze

Form

Liquid

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Description

  • The epitope recognized by 2A11 is sensitive to H2O2 treatment, therefore quenching with 0.3% H2O2 should be performed after incubation with the primary antibody
  • The epitope recognized by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing
  • We recommend the use of acetone fixation for frozen sections
  • For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
  • This product is a low-endotoxin, preservative-free formulation
  • Endotoxin level is <0.01 EU/ug
  • Rat anti Mouse Dectin-1 antibody, clone 2A11 recognizes murine beta-glucan receptor, also known as Dectin-1
  • CLEC7A, also known as dectin-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily and is predominantly expressed on myeloid cells
  • It is a small glycoprotein type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif (ITAM)
  • CLEC7A functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response
  • Upon fungal exposure, CLEC7A activates Syk tyrosine kinase, triggering a massive oxidative burst through the formation of reactive oxygen species.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA516478

--


Antigen:
Dectin 1 (soluble)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q6QLQ4

Gene Symbols:
Clec7a

Immunogen:
Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation

Clone:
2A11

Conjugate:
Unconjugated

Gene:
Clec7a

Gene Alias:
Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
56644

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

PIMA516479

--


Antigen:
Dectin 1 (soluble)

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 1% BSA and 0.09% sodium azide

Gene Accession No.:
Q6QLQ4

Gene Symbols:
Clec7a

Immunogen:
Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry

Clone:
2A11

Conjugate:
FITC

Gene:
Clec7a

Gene Alias:
Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
56644

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Thermo Scientific

PIMA516480

--


Antigen:
Dectin 1 (soluble)

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 1% BSA and 0.09% sodium azide

Gene Accession No.:
Q6QLQ4

Gene Symbols:
Clec7a

Immunogen:
Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry

Clone:
2A11

Conjugate:
FITC

Gene:
Clec7a

Gene Alias:
Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
56644

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Thermo Scientific

PIMA516481

--


Antigen:
Dectin 1 (soluble)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q6QLQ4

Gene Symbols:
Clec7a

Immunogen:
Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation

Clone:
2A11

Conjugate:
Unconjugated

Gene:
Clec7a

Gene Alias:
Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
56644

Content And Storage:
4° C, do not freeze

Form:
Liquid