PIMA516586

HLA-A2 Monoclonal Antibody (BB7.2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA516586-Each-of-1 In Stock ₹ 72,212.64

PIMA516586 - Each of 1

₹ 72,212.64

In Stock

Quantity

1

Base Price: ₹ 72,212.64

GST (18%): ₹ 12,998.275

Total Price: ₹ 85,210.915

Antigen

HLA-A2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P04439

Gene Symbols

HLA-A

Immunogen

Papain solubilised HLA-A2

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Applications

Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation

Clone

BB7.2

Conjugate

Unconjugated

Gene

HLA-A

Gene Alias

A29 protein; antigen presenting molecule; Aw-33; Aw-74; DAQB-90C11.16; FLJ26655; HLA A; HLA class I antigen; HLA class I histocompatibility antigen, A alpha chain; HLA class I histocompatibility antigen, A-1 alpha chain; HLA class I histocompatibility antigen, A-30 alpha chain; HLA class I histocompatibility antigen, A-33 alpha chain; HLA class I histocompatibility antigen, A-74 alpha chain; HLA locus; HLAA; HLA-A; HLA-A locus alpha 2 domain; HLA-A null; HLA-A11; HLA-A33; HLA-Aw33.1; HLA-DQB1; HLA-DRB1; Human leukocyte antigen A; leucocyte antigen A; leukocyte antigen class I-A; major histocompatibility complex, class I, A; MCH class I antigen; MHC 1; MHC class 1 antigen; MHC class I anti; MHC Class I antigen; MHC class I antigen A*30; MHC class I antigen A*33; MHC class I antigen A*74; MHC class I antigen heavy chain; MHC class I antigen HLA-A heavy chain; MHC class I antigen HLA-A33; MHC class I antigen null protein; MHC class I antigene; MHC class II antigen; MHC classI antigen; MHC1; truncated MHC class I antigen

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

3105

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • This product is a low-endotoxin, preservative-free formulation
  • Endotoxin level is <0.01EU/ug
  • For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
  • A suggested positive control for immunohistochemical applications is tonsil
  • Mouse anti Human HLA A2 antibody, clone BB7.2 recognizes the human HLA-A2 histocompatability antigen
  • HLA-A belongs to the HLA class I heavy chain paralogues
  • This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin)
  • The heavy chain is anchored in the membrane
  • Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen
  • They are expressed in nearly all cells
  • The heavy chain is approximately 45 kDa and its gene contains 8 exons
  • Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail
  • Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule
  • Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation
  • Hundreds of HLA-A alleles have been described
  • HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

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Img

Thermo Scientific

PIMA516586

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Antigen:
HLA-A2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P04439

Gene Symbols:
HLA-A

Immunogen:
Papain solubilised HLA-A2

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation

Clone:
BB7.2

Conjugate:
Unconjugated

Gene:
HLA-A

Gene Alias:
A29 protein; antigen presenting molecule; Aw-33; Aw-74; DAQB-90C11.16; FLJ26655; HLA A; HLA class I antigen; HLA class I histocompatibility antigen, A alpha chain; HLA class I histocompatibility antigen, A-1 alpha chain; HLA class I histocompatibility antigen, A-30 alpha chain; HLA class I histocompatibility antigen, A-33 alpha chain; HLA class I histocompatibility antigen, A-74 alpha chain; HLA locus; HLAA; HLA-A; HLA-A locus alpha 2 domain; HLA-A null; HLA-A11; HLA-A33; HLA-Aw33.1; HLA-DQB1; HLA-DRB1; Human leukocyte antigen A; leucocyte antigen A; leukocyte antigen class I-A; major histocompatibility complex, class I, A; MCH class I antigen; MHC 1; MHC class 1 antigen; MHC class I anti; MHC Class I antigen; MHC class I antigen A*30; MHC class I antigen A*33; MHC class I antigen A*74; MHC class I antigen heavy chain; MHC class I antigen HLA-A heavy chain; MHC class I antigen HLA-A33; MHC class I antigen null protein; MHC class I antigene; MHC class II antigen; MHC classI antigen; MHC1; truncated MHC class I antigen

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3105

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA516587

--


Antigen:
HLA-A2

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 1% BSA and 0.09% sodium azide

Gene Accession No.:
P04439

Gene Symbols:
HLA-A

Immunogen:
Papain solubilised HLA-A2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry

Clone:
BB7.2

Conjugate:
FITC

Gene:
HLA-A

Gene Alias:
A29 protein; antigen presenting molecule; Aw-33; Aw-74; DAQB-90C11.16; FLJ26655; HLA A; HLA class I antigen; HLA class I histocompatibility antigen, A alpha chain; HLA class I histocompatibility antigen, A-1 alpha chain; HLA class I histocompatibility antigen, A-30 alpha chain; HLA class I histocompatibility antigen, A-33 alpha chain; HLA class I histocompatibility antigen, A-74 alpha chain; HLA locus; HLAA; HLA-A; HLA-A locus alpha 2 domain; HLA-A null; HLA-A11; HLA-A33; HLA-Aw33.1; HLA-DQB1; HLA-DRB1; Human leukocyte antigen A; leucocyte antigen A; leukocyte antigen class I-A; major histocompatibility complex, class I, A; MCH class I antigen; MHC 1; MHC class 1 antigen; MHC class I anti; MHC Class I antigen; MHC class I antigen A*30; MHC class I antigen A*33; MHC class I antigen A*74; MHC class I antigen heavy chain; MHC class I antigen HLA-A heavy chain; MHC class I antigen HLA-A33; MHC class I antigen null protein; MHC class I antigene; MHC class II antigen; MHC classI antigen; MHC1; truncated MHC class I antigen

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3105

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form:
Liquid

Img

Thermo Scientific

PIMA516591

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Antigen:
BCAM

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
tris with glycine and <0.1% sodium azide

Gene Accession No.:
P50895

Gene Symbols:
BCAM

Immunogen:
Human erythrocytes

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Clone:
BRIC221

Conjugate:
Unconjugated

Gene:
BCAM

Gene Alias:
1200005K12Rik; antigen identified by monoclonal antibody F8; AU; Auberger B antigen; basal cell adhesion molecule; basal cell adhesion molecule (Lu and Au blood groups); basal cell adhesion molecule (Lutheran blood group); basal cell adhesion molecule Lutheran blood group; BCAM; B-CAM; B-CAM cell surface glycoprotein; B-cell adhesion molecule; CD239; F8/G253 antigen; glycoprotein 95kDa; Gplu; LU; lutheran antigen; Lutheran blood group; Lutheran blood group (Auberger b antigen included); Lutheran blood group glycoprotein; Lutheran blood group variant LUGA; lutheran glycoprotein; MSK19

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4059

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA516592

--


Antigen:
GYPC

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
TBS with ≤100mM glycine and <0.1% sodium azide

Gene Accession No.:
P04921

Gene Symbols:
GYPC

Immunogen:
Human erythrocytes

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Hemagglutination Assay, Immunohistochemistry (Frozen), Western Blot

Clone:
BRIC4

Conjugate:
Unconjugated

Gene:
GYPC

Gene Alias:
0610037F22Rik; CD236; CD236R; GE; Gerbich antigen; GLPC; Glycoconnectin; glycophorin C; glycophorin C (Gerbich blood group); glycophorin-C; Glycophorin-D; glycoprotein beta; GPC; GPD; GPYD; GYPC; GYPD; MGC117309; MGC126191; MGC126192; PAS-2; PAS-2'; Sialoglycoprotein D

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
2995

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid