CD8 Monoclonal Antibody (YCATE55.9), PE, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516988-Each-of-1 | In Stock | ₹ 89,495.76 |
PIMA516988 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 89,495.76
GST (18%): ₹ 16,109.237
Total Price: ₹ 1,05,604.997
Antigen
CD8
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene Accession No.
P33706
Gene Symbols
Cd8a, CD8B
Immunogen
Canine CD8 alpha chimaeric human IgG1 Fc fusion protein.
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Canine
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry
Clone
YCATE55.9
Conjugate
PE
Gene
Cd8a
Gene Alias
BB154331; CD8; CD8 alpha; CD8 alpha chain; CD8 alpha chain precursor; CD8 antigen; CD8 antigen 32 kDa chain; CD8 antigen 37 kDa chain; CD8 antigen alpha polypeptide; CD8 antigen alpha protein; CD8 antigen alpha protein precursor; CD8 antigen alpha-chain; CD8 antigen beta polypeptide; CD8 antigen beta polypeptide precursor; CD8 antigen beta-chain; CD8 antigen, alpha chain; CD8 antigen, alpha polypeptide; CD8 antigen, alpha polypeptide (p32); CD8 antigen, alpha-chain; CD8 antigen, beta chain; CD8 antigen, beta chain 1; CD8 antigen, beta polypeptide; CD8 antigen, beta polypeptide 1 (p37); CD8 antigen, beta-chain; CD8 beta; CD8 beta chain; CD8 beta-2; CD8a; CD8A antigen alpha; CD8a molecule; CD8A; T-cell surface glycoprotein; CD8alpha; CD8B; CD8b antigen; CD8b molecule; CD8b molecule pseudogene; Cd8b1; CD8beta; CD8BP; fCD8; LEU2; Leu-2; Leu2 T-lymphocyte antigen; leu-2a; Ly-2; LY3; Ly-3; Ly-35; Ly-B; Ly-C; Lymphocyte antigen 3; Lyt2; Lyt-2; Lyt-2.1 lymphocyte differentiation antigen (AA at 100); Lyt3; Lyt-3; MAL; membrane glycoprotein; membrane protein; OKT8 T-cell antigen; OX-8 membrane antigen; p32; P37; RHACD8-4; T cell co-receptor; T lymphocyte surface glycoprotein beta chain; T8 T-cell antigen; T-cell antigen Leu2; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-2; T-cell surface glycoprotein Lyt-3; T-cell surface molecule; T-lymphocyte differentiation antigen T8/Leu-2; type I transmembrane glycoprotein
Host Species
Rat
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
403157, 483076
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Lyophilized
Related Products
Description
- Reconstitute with 1 mL of distilled water
- After reconstitution, store product undiluted at 4oC in the dark
- For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
- Rat anti Dog CD8 antibody, clone YCATE55.9 was clustered as Canine CD8 in the First Canine Leukocyte Antigen Workshop (Cobbold et al
- 1994)
- Cluster of differentiation 8 (CD8), a type I transmembrane glycoprotein of the immunoglobulin family of receptors, plays an integral role in signal transduction, and T cell differentiation and activation
- CD8 is predominantly expressed on T cells as a disulfide-linked heterodimer of CD8alpha and CD8beta, where it functions as a co-receptor, along with T cell receptor (TCR), for major histocompatibilty complex class I (MHC-I) molecules; whereas its counterpart, CD4, acts as a co-receptor for MHC-II molecules
- CD8 exists on the cell surface, where the CD8alpha chain is essential for binding to MHC-I
- CD8 is also expressed on a subset of T cells, NK cells, monocytes and dendritic cells as disulfide-linked homodimers of CD8alpha
- Ligation of MHC-I/peptide complexes presented by antigen-presenting cells (APCs), triggers the recruitment of lymphocyte-specific protein tyrosine kinase (Lck), which leads to lymphokine production, motility and cytotoxic T lymphocyte (CTL) activation
- Once activated, CTLs play a crucial role in the clearance of pathogens and tumor cells
- Differentiation of naive CD8+ T cells into CTLs is strongly enhanced by IL-2, IL-12 and TGF-beta1.
Compare Similar Items
Show Difference
Antigen: CD8
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene Accession No.: P33706
Gene Symbols: Cd8a, CD8B
Immunogen: Canine CD8 alpha chimaeric human IgG1 Fc fusion protein.
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Canine
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry
Clone: YCATE55.9
Conjugate: PE
Gene: Cd8a
Gene Alias: BB154331; CD8; CD8 alpha; CD8 alpha chain; CD8 alpha chain precursor; CD8 antigen; CD8 antigen 32 kDa chain; CD8 antigen 37 kDa chain; CD8 antigen alpha polypeptide; CD8 antigen alpha protein; CD8 antigen alpha protein precursor; CD8 antigen alpha-chain; CD8 antigen beta polypeptide; CD8 antigen beta polypeptide precursor; CD8 antigen beta-chain; CD8 antigen, alpha chain; CD8 antigen, alpha polypeptide; CD8 antigen, alpha polypeptide (p32); CD8 antigen, alpha-chain; CD8 antigen, beta chain; CD8 antigen, beta chain 1; CD8 antigen, beta polypeptide; CD8 antigen, beta polypeptide 1 (p37); CD8 antigen, beta-chain; CD8 beta; CD8 beta chain; CD8 beta-2; CD8a; CD8A antigen alpha; CD8a molecule; CD8A; T-cell surface glycoprotein; CD8alpha; CD8B; CD8b antigen; CD8b molecule; CD8b molecule pseudogene; Cd8b1; CD8beta; CD8BP; fCD8; LEU2; Leu-2; Leu2 T-lymphocyte antigen; leu-2a; Ly-2; LY3; Ly-3; Ly-35; Ly-B; Ly-C; Lymphocyte antigen 3; Lyt2; Lyt-2; Lyt-2.1 lymphocyte differentiation antigen (AA at 100); Lyt3; Lyt-3; MAL; membrane glycoprotein; membrane protein; OKT8 T-cell antigen; OX-8 membrane antigen; p32; P37; RHACD8-4; T cell co-receptor; T lymphocyte surface glycoprotein beta chain; T8 T-cell antigen; T-cell antigen Leu2; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-2; T-cell surface glycoprotein Lyt-3; T-cell surface molecule; T-lymphocyte differentiation antigen T8/Leu-2; type I transmembrane glycoprotein
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 403157, 483076
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Lyophilized
Antigen: CD5
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene Accession No.: 0
Gene Symbols: Cd5
Immunogen: Concanavilin A activated canine peripheral blood cells.
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Canine
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry
Clone: YKIX322.3
Conjugate: APC
Gene: Cd5
Gene Alias: alanyl (membrane) aminopeptidase; alanyl aminopeptidase; alanyl aminopeptidase, membrane; aminopeptidase M; Aminopeptidase N; ANPEP; AP-M; APN; AP-N; CD antigen CD5; CD13; CD28; CD28 antigen (Tp44); CD28 molecule; Cd5; CD5 antigen; CD5 antigen (p56 62); CD5 antigen (p56-62); CD5 antigen p56-62; CD5 molecule; CD5 protein; CD74 antigen, invariant polypeptide of major; cell surface protein; costimulatory molecule B7 receptor CD28; fCD5; GP150; hAPN; LAP1; LEU1; Ly-1; Ly12; Ly-12; LyA; Ly-A; Lymphocyte antigen 1; Lymphocyte antigen CD5; lymphocyte antigen T1/Leu-1; Lyt-1; membrane alanyl aminopeptidase; microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; P150; Pan T cell; PEPN; T1; T-cell costimulatory molecule CD28; T-cell surface glycoprotein CD5; T-cell-specific surface glycoprotein CD28; unnamed protein product
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 612338
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Lyophilized
Antigen: CD52
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P31358
Gene Symbols: CD52
Immunogen: human lymphocytes
Quantity: 500 μg
Primary or Secondary: Primary
Target Species: Human, Rhesus Monkey
Product Type: Antibody
Isotype: IgG2b
Applications: Cytotoxicity Assay, ELISA, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: YTH34.5
Conjugate: Unconjugated
Gene: CD52
Gene Alias: AI463198; B7; B7-Ag; cambridge pathology 1 antigen; CAMPATH-1; CAMPATH-1 antigen; Cd52; CD52 antigen; CD52 antigen (CAMPATH-1 antigen); CD52 molecule; CDW52; CDW52 antigen (CAMPATH-1 antigen); CLS1; Epididymal secretory protein E5; epididymis secretory sperm binding protein Li 171mP; he5; HEL-S-171mP; human epididymis-specific protein 5; Lymphocyte differentiation antigen B7; Mb7
Host Species: Rat
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1043, 714429
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid