PIMA517054

p16INK4a Monoclonal Antibody (1D7D2), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA517054-Each-of-1 In Stock ₹ 53,731.68

PIMA517054 - Each of 1

₹ 53,731.68

In Stock

Quantity

1

Base Price: ₹ 53,731.68

GST (18%): ₹ 9,671.702

Total Price: ₹ 63,403.382

Antigen

p16INK4a

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

P42771

Gene Symbols

CDKN2A

Immunogen

Purified recombinant fragment of human CDKN2A (amino acids: 1-156) expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

1029

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

1D7D2

Conjugate

Unconjugated

Gene

CDKN2A

Gene Alias

Alternative reading frame; Arf; ARF-INK4a; CDK4 inhibitor p16 INK4; CDK4 inhibitor p16-INK4; CDK4I; CDKN2; Cdkn2a; cdkn2a {ECO:0000312; cell cycle inhibitor; cell cycle negative regulator beta; cell cycle regulator; CMM2; Cyclin dependent kinase 4 inhibitor A; cyclin dependent kinase inhibitor 2A; Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase 4 inhibitor A; Cyclin-dependent kinase inhibitor 2A; cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2a p16Ink4a; cyclin-dependent kinase inhibitor 2a p19Arf; cyclin-dependent kinase inhibitor 2A, isoform 1; cyclin-dependent kinase inhibitor 2A, isoform 2; cyclin-dependent kinase inhibitor 2A, isoform 3; cyclin-dependent kinase inhibitor 2A, isoforms 1/2; cyclin-dependent kinase inhibitor protein; EMBL:AAL76336.1, ECO:0000312; EMBL:AAL76338.1, ECO:0000312; HGNC:1787; inhibits CDK4; INK4; INK4A; Ink4a/Arf; INK4a-ARF; isoforms 1/2/3; Melanoma p16 inhibits CDK4; mitochondrial smARF; MLM; MTS1; MTS-1; Multiple tumor suppressor 1; P14; P14 P16; P14ARF; p16; p16(INK4a); p16Cdkn2a; P16INK4; p16-INK4; p16INK4a; p16-INK4a; P19; P19 TP16; p19<ARF>; P19ARF; Pctr1; RGD:2323}; TP16; Tumor suppressor ARF

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-17054 targets CDKN2A in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human samples
  • The MA5-17054 immunogen is purified recombinant fragment of human CDKN2A (amino acids: 1-156) expressed in E
  • Coli
  • MA5-17054 detects CDKN2A which has a predicted molecular weight of approximately 16.5kDa
  • This gene generates several transcript variants which differ in their first exons
  • At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase
  • The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants
  • This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, the E3 ubiquitin-protein ligase MDM2, a protein responsible for the degradation of p53
  • In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control
  • This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene.

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Img

Thermo Scientific

PIMA517054

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Antigen:
p16INK4a

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P42771

Gene Symbols:
CDKN2A

Immunogen:
Purified recombinant fragment of human CDKN2A (amino acids: 1-156) expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
1029

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
1D7D2

Conjugate:
Unconjugated

Gene:
CDKN2A

Gene Alias:
Alternative reading frame; Arf; ARF-INK4a; CDK4 inhibitor p16 INK4; CDK4 inhibitor p16-INK4; CDK4I; CDKN2; Cdkn2a; cdkn2a {ECO:0000312; cell cycle inhibitor; cell cycle negative regulator beta; cell cycle regulator; CMM2; Cyclin dependent kinase 4 inhibitor A; cyclin dependent kinase inhibitor 2A; Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase 4 inhibitor A; Cyclin-dependent kinase inhibitor 2A; cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2a p16Ink4a; cyclin-dependent kinase inhibitor 2a p19Arf; cyclin-dependent kinase inhibitor 2A, isoform 1; cyclin-dependent kinase inhibitor 2A, isoform 2; cyclin-dependent kinase inhibitor 2A, isoform 3; cyclin-dependent kinase inhibitor 2A, isoforms 1/2; cyclin-dependent kinase inhibitor protein; EMBL:AAL76336.1, ECO:0000312; EMBL:AAL76338.1, ECO:0000312; HGNC:1787; inhibits CDK4; INK4; INK4A; Ink4a/Arf; INK4a-ARF; isoforms 1/2/3; Melanoma p16 inhibits CDK4; mitochondrial smARF; MLM; MTS1; MTS-1; Multiple tumor suppressor 1; P14; P14 P16; P14ARF; p16; p16(INK4a); p16Cdkn2a; P16INK4; p16-INK4; p16INK4a; p16-INK4a; P19; P19 TP16; p19<ARF>; P19ARF; Pctr1; RGD:2323}; TP16; Tumor suppressor ARF

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA517056

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Antigen:
Chromogranin A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P10354, P10645, P26339

Gene Symbols:
Chga

Immunogen:
Purified recombinant fragment of human CHGA (amino acids: 87-252 ) expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
1113, 12652, 24258

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
1A6B6

Conjugate:
Unconjugated

Gene:
Chga

Gene Alias:
AL-11; AL26; Beta-granin; betagranin (N-terminal fragment of chromogranin A); catestatin; CgA; CHGA; ChrA; chromofungin; chromogranin A; chromogranin A (parathyroid secretory protein 1); chromogranin A precursor; chromogranin-A; CTNNB; DKFZp686D02253; EA-92; ER-37; ES-43; FLJ25606; FLJ37923; GE-25; GR-44; GV-19; LF-19; LOW QUALITY PROTEIN: chromogranin-A; MGC105435; Pancreastatin; Parastatin; parathyroid secretory protein 1; p-Glu serpinin precursor; pituitary secretory protein I; Serpinin; Serpinin-RRG; SL21; SP-I; SS-18; Vasostatin I; Vasostatin II; Vasostatin-1; Vasostatin-2; WA-8; WE-14

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA517057

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Antigen:
Cytokeratin 5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P13647, Q922U2

Gene Symbols:
KRT5

Immunogen:
Purified recombinant fragment of human CK5 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
110308, 3852

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
2C2

Conjugate:
Unconjugated

Gene:
KRT5

Gene Alias:
3300001P10Rik; 58 kDa cytokeratin; alpha keratin; AW146334; CK5; CK-5; ckii; ckii protein; cytokeratin 5; cytokeratin-5; DDD; DDD1; EBS2; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K5; keratin 5; keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin complex 2, basic, gene 5; keratin type II, tail domain; keratin, type II cytoskeletal 5; keratin, type II cytoskeletal 5; keratin 5; keratin-5; Krt2-5; KRT5; KRT5A; Sak57; Tfip8; tuftelin interacting protein 8; type II alpha-keratin IIA; type II cytokeratin; type-II keratin Kb5; wu:fb02h09; wu:fj02d02; wu:fk78b12; zfCKII

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA517063

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Antigen:
CYP1A1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P04798

Gene Symbols:
CYP1A1

Immunogen:
Purified recombinant fragment of human CYP1A1 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
1543

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Clone:
6G5

Conjugate:
Unconjugated

Gene:
CYP1A1

Gene Alias:
AHH; AHRR; aromatic compound inducible; aryl hydrocarbon hydroxylase; CP11; CYP; CYP1; Cyp1a1; Cyp1a-1; Cyp1a2; Cyp45c; Cypc45c; CYPIA1; cytochrome P1-450; cytochrome P1-450, dioxin-inducible; cytochrome P450 1A1; cytochrome P450 family 1 subfamily A member 1; cytochrome P450 family 1 subfamily a polypeptide 2; cytochrome P450 form 6; cytochrome P450 subfamily I (aromatic compound-inducible) member A1 (C6 form c) (C6 form c); cytochrome P450 subfamily I, polypeptide 1; cytochrome P450, 1a1; cytochrome P450, 1a1, aromatic compound inducible; cytochrome P450, family 1, subfamily a, polypeptide 1; cytochrome P450, subfamily I (aromatic compound-inducible), member A1 (C6, form c) (C6, form c); cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1; cytochrome P450-C; cytochrome P450MT2; Cytochrome P450MT2A; Cytochrome P450MT2B; Cytochrome P450-P1; dioxin-inducible; flavoprotein-linked monooxygenase; Hydroperoxy icosatetraenoate dehydratase; microsomal monooxygenase; P1-450; P450; P450 form 6; P450-1; P450-C; P450DX; P450form6; P-450MC; P450MT2; P450-P1; xenobiotic monooxygenase

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1