PIMA517103

ITGB1 Monoclonal Antibody (3B6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA517103-Each-of-1 In Stock ₹ 53,303.88

PIMA517103 - Each of 1

₹ 53,303.88

In Stock

Quantity

1

Base Price: ₹ 53,303.88

GST (18%): ₹ 9,594.698

Total Price: ₹ 62,898.578

Antigen

ITGB1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

P05556, P09055

Gene Symbols

ITGB1

Immunogen

Purified recombinant fragment of human ITGB1 expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone

3B6

Conjugate

Unconjugated

Gene

ITGB1

Gene Alias

4633401G24Rik; AA409975; AA960159; Beta OL; beta oligodendroglia; CD29; CSAT antigen; ENSMUSG00000051907; Fibronectin receptor subunit beta; FNRB; Glycoprotein IIa; Gm9863; gpIIa; integrin beta 1; integrin beta 1 (fibronectin receptor beta); integrin beta 1A precursor; Integrin beta1; integrin beta-1; integrin beta-1 subunit; integrin beta1D; integrin precursor; integrin subunit beta 1; integrin VLA-4 beta subunit; integrin VLA-4 subunit beta; integrin, beta 1; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); ITBG1D; ITGB1; JG22 antigen; MDF2; MSK12; RGD-receptor; very late activation protein, beta polypeptide; VLA-4 subunit beta; VLAB; VLA-BETA

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

16412, 3688

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • MA5-17103 targets ITGB1 in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human and Non-human primate samples
  • The MA5-17103 immunogen is purified recombinant fragment of human ITGB1 expressed in E
  • Coli
  • MA5-17103 detects ITGB1 which has a predicted molecular weight of approximately 88.4kDa
  • ITGB1 (Integrin Subunit Beta 1, beta1 integrin subunit, GPIIa, CD29) is a 110 kDa cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes
  • ITGB1 forms non-covalently linked heterodimers with at least 6 different alpha chains (alpha1-alpha6, CDa-f) determining the binding properties of beta1 (VLA) integrins
  • ITGB1 is a cell adhesion molecule appearing on platelets, as the common Beta subunit of the very late activation antigen (VLA), and as a component of various protein complexes binding to extracellular matrix proteins
  • Decreased expression of ITGB1 correlates with acquiring multidrug resistance of tumor cells in the presence of anti-tumor drug
  • ITGB1 is up-regulated in leukocytes during emigration and extravascular migration and appear to be critically involved in regulating the immune cell trafficking from blood to tissue
  • Further, ITGB1 also regulates tissue damage and disease symptoms related to inflammatory bowel disease
  • Through an ITGB1-dependent mechanism, fibronectin and type I collagen enhance cytokine secretion of human airway smooth muscle in response to IL-1beta
  • More than 8 beta subunits with numerous splice variant isoforms have been identified in mammals
  • There are two major forms of integrin beta1: beta1A and beta1D, which differ in 13 amino acids
  • The distribution pattern in adult tissues for integrin beta types are mutually exclusive
  • Beta1A is present in all tissues, except cardiac and skeletal muscle which express the beta1D variant.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA517103

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Antigen:
ITGB1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P05556, P09055

Gene Symbols:
ITGB1

Immunogen:
Purified recombinant fragment of human ITGB1 expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
3B6

Conjugate:
Unconjugated

Gene:
ITGB1

Gene Alias:
4633401G24Rik; AA409975; AA960159; Beta OL; beta oligodendroglia; CD29; CSAT antigen; ENSMUSG00000051907; Fibronectin receptor subunit beta; FNRB; Glycoprotein IIa; Gm9863; gpIIa; integrin beta 1; integrin beta 1 (fibronectin receptor beta); integrin beta 1A precursor; Integrin beta1; integrin beta-1; integrin beta-1 subunit; integrin beta1D; integrin precursor; integrin subunit beta 1; integrin VLA-4 beta subunit; integrin VLA-4 subunit beta; integrin, beta 1; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); ITBG1D; ITGB1; JG22 antigen; MDF2; MSK12; RGD-receptor; very late activation protein, beta polypeptide; VLA-4 subunit beta; VLAB; VLA-BETA

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
16412, 3688

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA517104

--


Antigen:
CD104

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P16144

Gene Symbols:
ITGB4

Immunogen:
Purified recombinant fragment of human ITGB4 (amino acids: 1619-1822) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
10B10D5

Conjugate:
Unconjugated

Gene:
ITGB4

Gene Alias:
AA407042; C230078O20; CD antigen CD104; CD104; CD104 antigen; GP150; integrin beta 4; integrin beta-4; integrin subunit beta 4; integrin, beta 4; Itgb4

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3691

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA517107

--


Antigen:
KEAP1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q14145

Gene Symbols:
Keap1

Immunogen:
Purified recombinant fragment of human KEAP1 (amino acids: 380-624 ) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
7G4B10

Conjugate:
Unconjugated

Gene:
Keap1

Gene Alias:
cytosolic inhibitor of Nrf2; INrf2; Keap1; kelch like ECH associated protein 1; Kelch-like ECH-associated protein 1; kelch-like family member 19; kelch-like protein 19; Kiaa0132; KLHL19; mKIAA0132; NRF2 cytosolic inhibitor; ring canal protein

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
9817

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA517109

--


Antigen:
Cytokeratin 13

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P13646

Gene Symbols:
KRT13

Immunogen:
Purified recombinant fragment of human KRT13 (amino acids: 143-295) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
3G4

Conjugate:
Unconjugated

Gene:
KRT13

Gene Alias:
47 kDa cytokeratin; CK13; CK-13; cytokeratin 13; cytokeratin-13; K13; K-13; Ka13; keratin 13; keratin 13, type I; keratin complex 1, acidic, gene 13; keratin, type I cytoskeletal 13; Keratin-13; Krt-1.13; Krt1-13; KRT13; krt13 {ECO:0000250; MGC161462; MGC3781; Type I keratin Ka13; UniProtKB:P13646}; WSN2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3860

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid