PIMA517139
iNOS Monoclonal Antibody (4E5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA517139-Each-of-1 | In Stock | ₹ 53,560.56 |
PIMA517139 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,560.56
GST (18%): ₹ 9,640.901
Total Price: ₹ 63,201.461
Antigen
iNOS
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P29477, P35228
Gene Symbols
Nos2
Immunogen
Purified recombinant fragment of human NOS2 expressed in E. Coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
4E5
Conjugate
Unconjugated
Gene
Nos2
Gene Alias
Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
18126, 4843
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- MA5-17139 targets NOS2 in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human and Mouse samples
- The MA5-17139 immunogen is purified recombinant fragment of human NOS2 expressed in E
- Coli
- MA5-17139 detects NOS2 which has a predicted molecular weight of approximately 131kDa
- iNOS (Inducible Nitric oxide, NO, NOS) is an inorganic, gaseous free radical that carries a variety of messages between cells
- Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO
- NO production is mediated by members of the nitric oxide synthase (NOS) family
- iNOS is expressed in liver and inducible by a combination of lipopolysaccharide and certain cytokines
- NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO
- Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) and endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned
- All NOS isoforms contain calmodulin, nicotinamide adenine dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) binding domains
- iNOS is found in a variety of cell types including macrophages, hepatocytes, synoviocytes, and smooth muscle cells
- Cytokines such as interferon-gamma (IFN), tumor necrosis factor (TNF), interleukin-1 and -2, and lipopolysaccarides (LPS) cause an increase in iNOS mRNA, protein, and activity levels
- Protein kinase C-stimulating agents exhibit the same effect on iNOS activity
- After cytokine induction, iNOS exhibits a delayed activity response which is then followed by a significant increase in NO production over a long period of time
- Three related iNOS pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17
- Diseases associated with iNOS dysfunction include achalasia and impotence.
Compare Similar Items
Show Difference
Antigen: iNOS
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: P29477, P35228
Gene Symbols: Nos2
Immunogen: Purified recombinant fragment of human NOS2 expressed in E. Coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 4E5
Conjugate: Unconjugated
Gene: Nos2
Gene Alias: Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 18126, 4843
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
iNOS
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
P29477, P35228
Gene Symbols:
Nos2
Immunogen:
Purified recombinant fragment of human NOS2 expressed in E. Coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
4E5
Conjugate:
Unconjugated
Gene:
Nos2
Gene Alias:
Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
18126, 4843
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: PBK
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: Q96KB5
Gene Symbols: PBK
Immunogen: Purified recombinant fragment of human PBK expressed in E. Coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 2C8
Conjugate: Unconjugated
Gene: PBK
Gene Alias: 2810434B10Rik; AW538537; Cancer/testis antigen 84; CT84; D14Ertd732e; epididymis luminal protein 164; HEL164; Lymphokine-activated killer T-cell-originated protein kinase; MAPKK-like protein kinase; Nori-3; PBK; PDZ binding kinase; PDZ-binding kinase; serine/threonine protein kinase; spermatogenesis-related protein kinase; SPK; T-LAK cell-originated protein kinase; TOPK
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 55872
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
PBK
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
Q96KB5
Gene Symbols:
PBK
Immunogen:
Purified recombinant fragment of human PBK expressed in E. Coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
2C8
Conjugate:
Unconjugated
Gene:
PBK
Gene Alias:
2810434B10Rik; AW538537; Cancer/testis antigen 84; CT84; D14Ertd732e; epididymis luminal protein 164; HEL164; Lymphokine-activated killer T-cell-originated protein kinase; MAPKK-like protein kinase; Nori-3; PBK; PDZ binding kinase; PDZ-binding kinase; serine/threonine protein kinase; spermatogenesis-related protein kinase; SPK; T-LAK cell-originated protein kinase; TOPK
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
55872
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: PDE1B
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q01064, Q01066
Gene Symbols: Pde1b
Immunogen: Purified recombinant fragment of human PDE1B (amino acids: 370-536) expressed in E. Coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone: 5C4A3
Conjugate: Unconjugated
Gene: Pde1b
Gene Alias: 63 a Cam PDE; 63 a Cam-PDE; 63 kDa Cam-PDE; anti-oxidant protein 2; Aop2; Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; calmodulin-stimulated phosphodiesterase PDE1B1; Cam PDE 1B; Cam PDE1B; cam-PDE 1B; cyclic nucleotide phosphodiesterase (CaM-PDE); EGK_03739; epididymis secretory sperm binding protein Li 79p; HEL-S-79p; PDE 1B; Pde1b; Pde1b1; PDES 1B; PDES1B; Phosphodiesterase; phosphodiesterase 1B; phosphodiesterase 1B, Ca2+calmodulin dependent; phosphodiesterase 1B, Ca2+-calmodulin dependent; phosphodiesterase 1B, Ca2+-calmodulin dependent, 63 kDa; phosphodiesterase 1B, calmodulin-dependent; phosphodiesterase 1B1 Ca2+-calmodulin dependent 63 kDa; phosphodiesterase 1B1, Ca2+-calmodulin dependent, 63 kDa; phosphodiesterase IB calmodulin-dependent; presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 29691, 5153
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
PDE1B
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q01064, Q01066
Gene Symbols:
Pde1b
Immunogen:
Purified recombinant fragment of human PDE1B (amino acids: 370-536) expressed in E. Coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone:
5C4A3
Conjugate:
Unconjugated
Gene:
Pde1b
Gene Alias:
63 a Cam PDE; 63 a Cam-PDE; 63 kDa Cam-PDE; anti-oxidant protein 2; Aop2; Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; calmodulin-stimulated phosphodiesterase PDE1B1; Cam PDE 1B; Cam PDE1B; cam-PDE 1B; cyclic nucleotide phosphodiesterase (CaM-PDE); EGK_03739; epididymis secretory sperm binding protein Li 79p; HEL-S-79p; PDE 1B; Pde1b; Pde1b1; PDES 1B; PDES1B; Phosphodiesterase; phosphodiesterase 1B; phosphodiesterase 1B, Ca2+calmodulin dependent; phosphodiesterase 1B, Ca2+-calmodulin dependent; phosphodiesterase 1B, Ca2+-calmodulin dependent, 63 kDa; phosphodiesterase 1B, calmodulin-dependent; phosphodiesterase 1B1 Ca2+-calmodulin dependent 63 kDa; phosphodiesterase 1B1, Ca2+-calmodulin dependent, 63 kDa; phosphodiesterase IB calmodulin-dependent; presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
29691, 5153
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: PDX1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: P52945
Gene Symbols: PDX1
Immunogen: Purified recombinant fragment of human PDX1 expressed in E. Coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Flow Cytometry, Western Blot
Clone: 5A5
Conjugate: Unconjugated
Gene: PDX1
Gene Alias: DLDBP; E3BP; Glucose-sensitive factor; GSF; Idx1; IDX-1; Insulin promoter factor 1; insulin promoter factor 1, homeodomain transcription factor; insulin promotor factor 1; insulin upstream factor 1; Ipf1; IPF-1; Islet/duodenum homeobox 1; islet/duodenum homeobox-1; IUF1; IUF-1; MODY4; PAGEN1; Pancreas/duodenum homeobox protein 1; pancreatic and duodenal homeobox 1; pancreatic and duodenal homeobox gene 1; pancreatic-duodenal homeobox factor 1; PDHX; PDX1; pdx-1; somatostatin transactivating factor 1; somatostatin transcription factor 1; somatostatin-transactivating factor 1; Stf1; STF-1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 3651
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
PDX1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
P52945
Gene Symbols:
PDX1
Immunogen:
Purified recombinant fragment of human PDX1 expressed in E. Coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Flow Cytometry, Western Blot
Clone:
5A5
Conjugate:
Unconjugated
Gene:
PDX1
Gene Alias:
DLDBP; E3BP; Glucose-sensitive factor; GSF; Idx1; IDX-1; Insulin promoter factor 1; insulin promoter factor 1, homeodomain transcription factor; insulin promotor factor 1; insulin upstream factor 1; Ipf1; IPF-1; Islet/duodenum homeobox 1; islet/duodenum homeobox-1; IUF1; IUF-1; MODY4; PAGEN1; Pancreas/duodenum homeobox protein 1; pancreatic and duodenal homeobox 1; pancreatic and duodenal homeobox gene 1; pancreatic-duodenal homeobox factor 1; PDHX; PDX1; pdx-1; somatostatin transactivating factor 1; somatostatin transcription factor 1; somatostatin-transactivating factor 1; Stf1; STF-1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
3651
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid