PIMA517424

CD45 Monoclonal Antibody (OX-1), FITC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA517424-Each-of-1 In Stock ₹ 48,041.94

PIMA517424 - Each of 1

₹ 48,041.94

In Stock

Quantity

1

Base Price: ₹ 48,041.94

GST (18%): ₹ 8,647.549

Total Price: ₹ 56,689.489

Antigen

CD45

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.

P04157

Gene Symbols

PTPRC

Immunogen

Rat thymocyte membrane glycoproteins

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Rat

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry

Clone

OX-1

Conjugate

FITC

Gene

PTPRC

Gene Alias

B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

24699

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA517423

--

Img

Thermo Scientific

PIMA517377

--

Img

Thermo Scientific

PIMA190812

--

Img

Thermo Scientific

PIMA517378

--

Img

Thermo Scientific

PIMA517422

--

Img

Thermo Scientific

PIMA517425

--

Img

Thermo Scientific

PIMA517374

--

Img

Thermo Scientific

PIMA517961

--

Description

  • CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes
  • CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues
  • CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
  • CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains
  • CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells
  • CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
  • CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling and suppresses JAK kinases to regulate cytokine receptor signaling
  • CD45 is also important in promoting cell survival by modulating integrin-mediated signal transduction pathway, DNA fragmentation during apoptosis and inhibition or upregulation of various immunological functions.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA517424

--


Antigen:
CD45

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
P04157

Gene Symbols:
PTPRC

Immunogen:
Rat thymocyte membrane glycoproteins

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
OX-1

Conjugate:
FITC

Gene:
PTPRC

Gene Alias:
B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
24699

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form:
Liquid

Img

Thermo Scientific

PIMA517425

--


Antigen:
CD45

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
P04157

Gene Symbols:
PTPRC

Immunogen:
Rat thymocyte membrane glycoproteins

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
OX-1

Conjugate:
PE

Gene:
PTPRC

Gene Alias:
B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
24699

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

PIMA517427

--


Antigen:
RT1.B

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
0

Gene Symbols:
RT1-B

Immunogen:
Rat thymocyte membrane glycoprotein.

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Clone:
OX-6

Conjugate:
Unconjugated

Gene:
RT1-B

Gene Alias:
rat class I B; RT1 class II, locus B; RT1-B

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
24738

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA517429

--


Antigen:
RT1.B

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
0

Gene Symbols:
RT1-B

Immunogen:
Rat thymocyte membrane glycoprotein

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Clone:
OX-6

Conjugate:
Biotin

Gene:
RT1-B

Gene Alias:
rat class I B; RT1 class II, locus B; RT1-B

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
24738

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid