PIMA517539

KLRB1 Monoclonal Antibody (10-78), FITC, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA517539-Each-of-1 In Stock ₹ 48,041.94

PIMA517539 - Each of 1

₹ 48,041.94

In Stock

Quantity

1

Base Price: ₹ 48,041.94

GST (18%): ₹ 8,647.549

Total Price: ₹ 56,689.489

Antigen

KLRB1

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.

A4KWA1, P27471, Q0ZUP0

Gene Symbols

Klrb1, Klrb1a, Klrb1b

Immunogen

60 kDa disulfide linked homodimer NKR-P1

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Rat

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Western Blot

Clone

10-78

Conjugate

FITC

Gene

Klrb1a

Gene Alias

4930431A04Rik; Antigen 3.2.3; CD161; CD161 antigen-like family member A; CD161 antigen-like family member B; CD161a; CD161b; CLEC5B; C-type lectin domain family 5 member B; EMBL:AAQ11375.1}; Gm4696; HNKR-P1a; Immunoreceptor NKR-P1E; immunoreceptor NKR-P1G; inhibitory receptor NKR-P1B; killer cell lectin like receptor B1; killer cell lectin-like receptor subfamily A member 1 complex; killer cell lectin-like receptor subfamily B member 1; killer cell lectin-like receptor subfamily B member 1 complex; killer cell lectin-like receptor subfamily B member 1A; killer cell lectin-like receptor subfamily B member 1B; killer cell lectin-like receptor subfamily B member 1B allele A; Killer cell lectin-like receptor subfamily B member 1B allele B; killer cell lectin-like receptor subfamily B member 1B allele C; killer cell lectin-like receptor subfamily B member 1D; killer cell lectin-like receptor subfamily B member 1F; killer cell lectin-like receptor subfamily B member 1G; killer cell lectin-li

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

25192, 362443, 689817

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form

Liquid

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Description

  • KLRB1 (Killer cell lectin like receptor subfamily B, member 1, CD-161) protein is classified as a type II membrane protein because it has an external C terminus
  • KLRB1 cell surface antigen is expressed by almost all NK cells and in a small subset of CD3+ve T cells
  • KLRB1 is a homodimeric cell surface protein, comprising two chains with molecular weights ranging from 40-44kDa
  • KLRB1 plays an inhibitory role on natural killer (NK) cells
  • Activation of KLRB1 leads to acid sphingomyelnase/SMPD1 stimulation and an increase in intracellular ceramide
  • Moreover, there is also an activation of AKT1/PKB and RPS6KA1/RSK1 kinase stimulation, and T cell proliferation by anti-CD3
  • KLRB1 acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope and to the N-acetyllactosamine epitope
  • KLRB1 also binds to CLEC2D/LLT1 as a ligand, and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells
  • The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain.

Compare Similar Items

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Img

Thermo Scientific

PIMA517539

--


Antigen:
KLRB1

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
A4KWA1, P27471, Q0ZUP0

Gene Symbols:
Klrb1, Klrb1a, Klrb1b

Immunogen:
60 kDa disulfide linked homodimer NKR-P1

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Western Blot

Clone:
10-78

Conjugate:
FITC

Gene:
Klrb1a

Gene Alias:
4930431A04Rik; Antigen 3.2.3; CD161; CD161 antigen-like family member A; CD161 antigen-like family member B; CD161a; CD161b; CLEC5B; C-type lectin domain family 5 member B; EMBL:AAQ11375.1}; Gm4696; HNKR-P1a; Immunoreceptor NKR-P1E; immunoreceptor NKR-P1G; inhibitory receptor NKR-P1B; killer cell lectin like receptor B1; killer cell lectin-like receptor subfamily A member 1 complex; killer cell lectin-like receptor subfamily B member 1; killer cell lectin-like receptor subfamily B member 1 complex; killer cell lectin-like receptor subfamily B member 1A; killer cell lectin-like receptor subfamily B member 1B; killer cell lectin-like receptor subfamily B member 1B allele A; Killer cell lectin-like receptor subfamily B member 1B allele B; killer cell lectin-like receptor subfamily B member 1B allele C; killer cell lectin-like receptor subfamily B member 1D; killer cell lectin-like receptor subfamily B member 1F; killer cell lectin-like receptor subfamily B member 1G; killer cell lectin-li

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
25192, 362443, 689817

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form:
Liquid

Img

Thermo Scientific

PIMA517540

--


Antigen:
KLRB1

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
A4KWA1, P27471, Q0ZUP0

Gene Symbols:
Klrb1, Klrb1a, Klrb1b

Immunogen:
60 kDa disulfide linked homodimer NKR-P1

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
10-78

Conjugate:
PE

Gene:
Klrb1

Gene Alias:
4930431A04Rik; Antigen 3.2.3; CD161; CD161 antigen-like family member A; CD161 antigen-like family member B; CD161a; CD161b; CLEC5B; C-type lectin domain family 5 member B; EMBL:AAQ11375.1}; Gm4696; HNKR-P1a; Immunoreceptor NKR-P1E; immunoreceptor NKR-P1G; inhibitory receptor NKR-P1B; killer cell lectin like receptor B1; killer cell lectin-like receptor subfamily A member 1 complex; killer cell lectin-like receptor subfamily B member 1; killer cell lectin-like receptor subfamily B member 1 complex; killer cell lectin-like receptor subfamily B member 1A; killer cell lectin-like receptor subfamily B member 1B; killer cell lectin-like receptor subfamily B member 1B allele A; Killer cell lectin-like receptor subfamily B member 1B allele B; killer cell lectin-like receptor subfamily B member 1B allele C; killer cell lectin-like receptor subfamily B member 1D; killer cell lectin-like receptor subfamily B member 1F; killer cell lectin-like receptor subfamily B member 1G; killer cell lectin-like receptor subfamily B, member 1; killer cell lectin-like receptor subfamily B, member 1A; Klrb1; Klrb1a; Klrb1b; klrb1b {ECO:0000312; Klrb1d; Klrb1f; Klrb1g; Klrb6; lectin-like transmembrane protein Nkrp1g; Ly55; Ly-55; Ly55a; ly-55A; Ly55b; ly-55b; Ly55d; ly-55d; lymphocyte antigen 55; lymphocyte antigen 55 complex, locus A; lymphocyte antigen 55 complex, locus B; lymphocyte antigen 55 complex, locus D; lymphocyte antigen 55A; lymphocyte antigen 55b; lymphocyte antigen 55d; MGC138614; natural killer cell receptor; natural killer cell receptor protein NKR-P1A; natural killer cell receptor protein NKR-P1B; natural killer cell receptor-P1; natural killer cell surface protein NKR-P1B allele B6; Natural killer cell surface protein NKR-P1B allele RNK/SD/BN/F344; natural killer cell surface protein NKR-P1B allele SJL/BALB; natural killer cell surface protein NKR-P1B allele TO; natural killer cell surface protein NKR-P1G; Natural killer cell surface protein P1-2; natural killer cell surface protein P1-3.2.3; Natural killer cell surface protein P1A; natural killer lectin-like receptor 1E; natural killer lectin-like receptor protein 1 e; NKR; NKR-P1; NKR-P1 2; NKR-P1 3.2.3; NKR-P1 34; NKR-P1.7; NKRP12; NKRP1A; NKR-P1A; Nkrp1-a; Nkrp1b; Nkr-p1b; Nkrp1-b; Nkrp1d; NKR-P1D; Nkrp1e; Nkr-p1e; Nkrp-1e; Nkrp1g; NKR-P1G; RGD:2975}

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
25192, 362443, 689817

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

PIMA517541

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Antigen:
TCR alpha/beta

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
0

Gene Symbols:
LOC290071, Tcrb

Immunogen:
Rat T Blasts.

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation

Clone:
R73

Conjugate:
Unconjugated

Gene:
Tcrb

Gene Alias:
FLJ22602; IMD7; LOC290071; MGC117436; MGC22624; MGC23964; MGC71411; RATTCB; RATTCBC1; RGD1359684; similar to RIKEN cDNA A430107P09 gene; T cell receptor beta locus; T3/TCR complex; TCB; TCBC1; t-cell antigen receptor; T-cell receptor alpha constant; T-cell receptor beta chain; T-cell receptor V alpha; tcr alpha; TCR alpha/ beta; TCR beta; TCRA; Tcrb; TRA; Tra29; TRAC; TRB; TRB@; TRCA

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
24820, 290071

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA517542

--


Antigen:
TCR alpha/beta

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
0

Gene Symbols:
LOC290071, Tcrb

Immunogen:
Rat T Blasts

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunohistochemistry (Frozen)

Clone:
R73

Conjugate:
Biotin

Gene:
LOC290071

Gene Alias:
FLJ22602; IMD7; LOC290071; MGC117436; MGC22624; MGC23964; MGC71411; RATTCB; RATTCBC1; RGD1359684; similar to RIKEN cDNA A430107P09 gene; T cell receptor beta locus; T3/TCR complex; TCB; TCBC1; t-cell antigen receptor; T-cell receptor alpha constant; T-cell receptor beta chain; T-cell receptor V alpha; tcr alpha; TCR alpha/ beta; TCR beta; TCRA; Tcrb; TRA; Tra29; TRAC; TRB; TRB@; TRCA

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
24820, 290071

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid