PIMA517605

CD8 alpha Monoclonal Antibody (YTS169.4), FITC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA517605-Each-of-1 In Stock ₹ 43,336.14

PIMA517605 - Each of 1

₹ 43,336.14

In Stock

Quantity

1

Base Price: ₹ 43,336.14

GST (18%): ₹ 7,800.505

Total Price: ₹ 51,136.645

Antigen

CD8 alpha

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.

P01731, P10300

Gene Symbols

Cd8a, Cd8b1

Immunogen

Mouse Ly-2 thymocytes

Quantity

300 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2b

Applications

Flow Cytometry

Clone

YTS169.4

Conjugate

FITC

Gene

Cd8a

Gene Alias

BB154331; CD8; CD8 alpha; CD8 alpha chain; CD8 alpha chain precursor; CD8 antigen; CD8 antigen 32 kDa chain; CD8 antigen 37 kDa chain; CD8 antigen alpha polypeptide; CD8 antigen alpha protein; CD8 antigen alpha protein precursor; CD8 antigen alpha-chain; CD8 antigen beta polypeptide; CD8 antigen beta polypeptide precursor; CD8 antigen beta-chain; CD8 antigen, alpha chain; CD8 antigen, alpha polypeptide; CD8 antigen, alpha polypeptide (p32); CD8 antigen, alpha-chain; CD8 antigen, beta chain; CD8 antigen, beta chain 1; CD8 antigen, beta polypeptide; CD8 antigen, beta polypeptide 1 (p37); CD8 antigen, beta-chain; CD8 beta; CD8 beta chain; CD8 beta-2; CD8a; CD8A antigen alpha; CD8a molecule; CD8A; T-cell surface glycoprotein; CD8alpha; CD8B; CD8b antigen; CD8b molecule; CD8b molecule pseudogene; Cd8b1; CD8beta; CD8BP; fCD8; LEU2; Leu-2; Leu2 T-lymphocyte antigen; leu-2a; Ly-2; LY3; Ly-3; Ly-35; Ly-B; Ly-C; Lymphocyte antigen 3; Lyt2; Lyt-2; Lyt-2.1 lymphocyte differentiation antigen (AA at

Host Species

Rat

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

12525, 12526

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form

Liquid

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Description

  • Cluster of differentiation 8 (CD8), a type I transmembrane glycoprotein of the immunoglobulin family of receptors, plays an integral role in signal transduction, and T cell differentiation and activation
  • CD8 is predominantly expressed on T cells as a disulfide-linked heterodimer of CD8alpha and CD8beta, where it functions as a co-receptor, along with T cell receptor (TCR), for major histocompatibilty complex class I (MHC-I) molecules; whereas its counterpart, CD4, acts as a co-receptor for MHC-II molecules
  • CD8 exists on the cell surface, where the CD8alpha chain is essential for binding to MHC-I
  • CD8 is also expressed on a subset of T cells, NK cells, monocytes and dendritic cells as disulfide-linked homodimers of CD8alpha
  • Ligation of MHC-I/peptide complexes presented by antigen-presenting cells (APCs), triggers the recruitment of lymphocyte-specific protein tyrosine kinase (Lck), which leads to lymphokine production, motility and cytotoxic T lymphocyte (CTL) activation
  • Once activated, CTLs play a crucial role in the clearance of pathogens and tumor cells
  • Differentiation of naive CD8+ T cells into CTLs is strongly enhanced by IL-2, IL-12 and TGF-beta1.

Compare Similar Items

Show Difference

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Thermo Scientific

PIMA517605

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Antigen:
CD8 alpha

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
P01731, P10300

Gene Symbols:
Cd8a, Cd8b1

Immunogen:
Mouse Ly-2 thymocytes

Quantity:
300 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry

Clone:
YTS169.4

Conjugate:
FITC

Gene:
Cd8a

Gene Alias:
BB154331; CD8; CD8 alpha; CD8 alpha chain; CD8 alpha chain precursor; CD8 antigen; CD8 antigen 32 kDa chain; CD8 antigen 37 kDa chain; CD8 antigen alpha polypeptide; CD8 antigen alpha protein; CD8 antigen alpha protein precursor; CD8 antigen alpha-chain; CD8 antigen beta polypeptide; CD8 antigen beta polypeptide precursor; CD8 antigen beta-chain; CD8 antigen, alpha chain; CD8 antigen, alpha polypeptide; CD8 antigen, alpha polypeptide (p32); CD8 antigen, alpha-chain; CD8 antigen, beta chain; CD8 antigen, beta chain 1; CD8 antigen, beta polypeptide; CD8 antigen, beta polypeptide 1 (p37); CD8 antigen, beta-chain; CD8 beta; CD8 beta chain; CD8 beta-2; CD8a; CD8A antigen alpha; CD8a molecule; CD8A; T-cell surface glycoprotein; CD8alpha; CD8B; CD8b antigen; CD8b molecule; CD8b molecule pseudogene; Cd8b1; CD8beta; CD8BP; fCD8; LEU2; Leu-2; Leu2 T-lymphocyte antigen; leu-2a; Ly-2; LY3; Ly-3; Ly-35; Ly-B; Ly-C; Lymphocyte antigen 3; Lyt2; Lyt-2; Lyt-2.1 lymphocyte differentiation antigen (AA at

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
12525, 12526

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form:
Liquid

Img

Thermo Scientific

PIMA517608

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Antigen:
VAMP1/VAMP2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P23763, P63027

Gene Symbols:
VAMP1, VAMP2

Immunogen:
Human Synaptobrevin 1 (aa 1-118) and Synaptobrevin 2(aa 33-96).

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgM

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
SP10

Conjugate:
Unconjugated

Gene:
VAMP1

Gene Alias:
RATVAMPB; RATVAMPIR; SPAX1; SYB; SYB1; SYB2; synaptobrevin 1; synaptobrevin 2; Synaptobrevin 2 (vesicle-associated membrane protein VAMP-2); synaptobrevin-1; Synaptobrevin-2; Vamp1; VAMP-1; VAMP2; VAMP-2; vesicle associated membrane protein 1; vesicle associated membrane protein 2; Vesicle-associated membrane protein (synaptobrevin 2); vesicle-associated membrane protein 1; vesicle-associated membrane protein 1 (synaptobrevin 1); vesicle-associated membrane protein 2; vesicle-associated membrane protein 2 (synaptobrevin 2)

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6843, 6844

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

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PIMA517610

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Antigen:
SNAP25

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
P60880

Gene Symbols:
Snap25

Immunogen:
Synaptic preparation of post mortem human brain

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
SP12

Conjugate:
Biotin

Gene:
Snap25

Gene Alias:
ALMS1; bA416N4.2; Bdr; blind drunk; CG17676; CG17884; CG40452; CMS18; dJ1068F16.2; Dmel CG40452; Dmel_CG40452; etID17571.20; etID69167.20; fj42b02; fj45g04; fj48c02; FLJ23079; GENA70; HGNC:11132; resistance to inhibitors of cholinesterase 4 homolog; RIC4; RIC-4; SEC9; si:dkeyp-8f4.6; Snap; SNAP 25; snap25; SNAP-25; snap25.1; SNAP-25.1; snap25a; SNAP-25A; SNAP-25B; snp25; sp; SUP; super protein; synaptosomal associated protein-25; synaptosomal-associated 25 kDa protein; Synaptosomal-associated protein 25; synaptosomal-associated protein 25-A; synaptosomal-associated protein, 25 kDa; synaptosomal-associated protein, 25a; synaptosomal-associated protein, 25kDa; synaptosome associated protein 25; synaptosome associated protein 25a; synaptosome associated protein 25kDa; synaptosome-associated protein 25.1; synaptosome-associated protein 25a; wu:fj42b02; wu:fj45g04; wu:fj48c02

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6616

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA517611

--


Antigen:
SNAP25

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
P60880

Gene Symbols:
Snap25

Immunogen:
Synaptic preparation of post mortem human brain

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
SP12

Conjugate:
FITC

Gene:
Snap25

Gene Alias:
ALMS1; bA416N4.2; Bdr; blind drunk; CG17676; CG17884; CG40452; CMS18; dJ1068F16.2; Dmel CG40452; Dmel_CG40452; etID17571.20; etID69167.20; fj42b02; fj45g04; fj48c02; FLJ23079; GENA70; HGNC:11132; resistance to inhibitors of cholinesterase 4 homolog; RIC4; RIC-4; SEC9; si:dkeyp-8f4.6; Snap; SNAP 25; snap25; SNAP-25; snap25.1; SNAP-25.1; snap25a; SNAP-25A; SNAP-25B; snp25; sp; SUP; super protein; synaptosomal associated protein-25; synaptosomal-associated 25 kDa protein; Synaptosomal-associated protein 25; synaptosomal-associated protein 25-A; synaptosomal-associated protein, 25 kDa; synaptosomal-associated protein, 25a; synaptosomal-associated protein, 25kDa; synaptosome associated protein 25; synaptosome associated protein 25a; synaptosome associated protein 25kDa; synaptosome-associated protein 25.1; synaptosome-associated protein 25a; wu:fj42b02; wu:fj45g04; wu:fj48c02

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6616

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form:
Liquid