PIMA517859

CD11b Monoclonal Antibody (M1/70.15), FITC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA517859-Each-of-1 In Stock ₹ 36,876.36

PIMA517859 - Each of 1

₹ 36,876.36

In Stock

Quantity

1

Base Price: ₹ 36,876.36

GST (18%): ₹ 6,637.745

Total Price: ₹ 43,514.105

Antigen

CD11b

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.

P05555

Gene Symbols

ITGAM

Immunogen

C57BL/6 spleen cell enriched for T lymphocytes

Quantity

300 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2b

Applications

Flow Cytometry

Clone

M1/70.15

Conjugate

FITC

Gene

ITGAM

Gene Alias

antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product

Host Species

Rat

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

16409

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form

Liquid

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Description

  • MA5-17859 targets CD11b/ITGAM/Integrin alpha M in FACS applications and shows reactivity with Mouse samples
  • The MA5-17859 immunogen is c57BL/6 spleen cell enriched for T lymphocytes
  • CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18)
  • The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3)
  • CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain
  • CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions
  • CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue
  • The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages
  • Further, peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages
  • Diseases associated with CD11b dysfunction include systemic lupus erythematosus 6 and ITGAM-related susceptibility to systemic lupus erythematosus.

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Thermo Scientific

PIMA517859

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Antigen:
CD11b

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
P05555

Gene Symbols:
ITGAM

Immunogen:
C57BL/6 spleen cell enriched for T lymphocytes

Quantity:
300 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry

Clone:
M1/70.15

Conjugate:
FITC

Gene:
ITGAM

Gene Alias:
antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
16409

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form:
Liquid

Img

Thermo Scientific

PIMA517860

--


Antigen:
CD11b

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
P05555

Gene Symbols:
ITGAM

Immunogen:
C57BL/6 spleen cell enriched for T lymphocytes

Quantity:
300 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry

Clone:
M1/70.15

Conjugate:
PE

Gene:
ITGAM

Gene Alias:
antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
16409

Content And Storage:
4° C, do not freeze

Form:
Liquid

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PIMA517863

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Antigen:
LAMP2

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
P17047

Gene Symbols:
LAMP2

Immunogen:
Immunoadsorbent purified mouse macrophage glycoprotein fraction.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunohistochemistry (Frozen)

Clone:
M3/84

Conjugate:
Biotin

Gene:
LAMP2

Gene Alias:
CD107 antigen-like family member B; CD107b; EGK_20887; Igp96; Lamp II; LAMP2; LAMP-2; LAMP-2 Isoform 2A; LAMP-2 Variant A; Lamp-2a; Lamp-2b; Lamp-2c; LAMPB; LGP110; LGP-110; LGP-96; LGP-B; lysosomal associated membrane protein 2; lysosomal membrane glycoprotein 2; lysosomal membrane glycoprotein type B; lysosomal-associated membrane protein 2; lysosome-associated membrane glycoprotein 2; lysosome-associated membrane protein 2; Mac3; RP23-193O17.2

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
16784

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA517864

--


Antigen:
LAMP2

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
P17047

Gene Symbols:
LAMP2

Immunogen:
Immunoadsorbent purified mouse macrophage glycoprotein fraction.

Quantity:
300 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunohistochemistry (Frozen)

Clone:
M3/84

Conjugate:
Biotin

Gene:
LAMP2

Gene Alias:
CD107 antigen-like family member B; CD107b; EGK_20887; Igp96; Lamp II; LAMP2; LAMP-2; LAMP-2 Isoform 2A; LAMP-2 Variant A; Lamp-2a; Lamp-2b; Lamp-2c; LAMPB; LGP110; LGP-110; LGP-96; LGP-B; lysosomal associated membrane protein 2; lysosomal membrane glycoprotein 2; lysosomal membrane glycoprotein type B; lysosomal-associated membrane protein 2; lysosome-associated membrane glycoprotein 2; lysosome-associated membrane protein 2; Mac3; RP23-193O17.2

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
16784

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid