PIMA518073
Progerin Monoclonal Antibody (13A4D4), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA518073-Each-of-1 | In Stock | ₹ 57,154.08 |
PIMA518073 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 57,154.08
GST (18%): ₹ 10,287.734
Total Price: ₹ 67,441.814
Antigen
Progerin
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
P02545
Gene Symbols
LMNA
Immunogen
Synthetic peptide conjugated to KLH derived from within residues 604-611 (GAQSPQNC) at the C terminus of Human Progerin
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Applications
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
13A4D4
Conjugate
Unconjugated
Gene
LMNA
Gene Alias
70 kDa lamin; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; lamin; lamin A/C; lamin A/C-like 1; Lamin AC; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; LMNA; LMNC; LMNL1; Mutant lamin A/C; Prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
4000
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody specifically recognizes Progerin (Lamin A delta50) and does not cross-react with endogenous prelamin A
- Western blot results show a band at approximately 70 kDa
- Progerin is a 614 amino acid protein involved in Hutchinson-Gilford progeria syndrome
- Progerin is most often generated by a point mutation (C1824T) in the LMNA gene that codes for lamin-A/C
- This mutation activates a cryptic splice site and gives rise to a form of lamin A with a 50-amino acid internal deletion within the C-terminal domain of the protein
- Approximately 80% of Hutchinson-Gilford progeria syndrome cases carry a single copy of the most common mutation, a silent point mutation, G608G (GGC > GGT), within exon 11 of the LMNA gene.
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Antigen: Progerin
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: P02545
Gene Symbols: LMNA
Immunogen: Synthetic peptide conjugated to KLH derived from within residues 604-611 (GAQSPQNC) at the C terminus of Human Progerin
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 13A4D4
Conjugate: Unconjugated
Gene: LMNA
Gene Alias: 70 kDa lamin; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; lamin; lamin A/C; lamin A/C-like 1; Lamin AC; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; LMNA; LMNC; LMNL1; Mutant lamin A/C; Prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 4000
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Progerin
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
P02545
Gene Symbols:
LMNA
Immunogen:
Synthetic peptide conjugated to KLH derived from within residues 604-611 (GAQSPQNC) at the C terminus of Human Progerin
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
13A4D4
Conjugate:
Unconjugated
Gene:
LMNA
Gene Alias:
70 kDa lamin; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; lamin; lamin A/C; lamin A/C-like 1; Lamin AC; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; LMNA; LMNC; LMNL1; Mutant lamin A/C; Prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
4000
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: H4K20me3
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: P62805, Q27894
Gene Symbols: H4-16, H4C1, H4C11, H4C14, H4C2, H4C5, H4C9, his-4
Immunogen: Synthetic peptide of Human Histone H4 (Immunogen sequence: 15-AKRHR(Kme3)VLRDN-25 (branched))
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: C. elegans, Human
Product Type: Antibody
Isotype: IgG1
Applications: ChIP Assay, Dot Blot, ELISA, Western Blot
Clone: 6F8-D9
Conjugate: Unconjugated
Gene: H4C1
Gene Alias: CELE_T10C6.11; F07B7.11; F07B7.4; F45F2.12; FO108; H4; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4 K20; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/j; H4/K; H4/M; H4/n; H4/O; H4/p; H4-12; H4-16; H4-53; H4C1; H4c11; H4C12; H4C13; H4c14; H4C15; H4C2; H4C3; H4C4; H4C5; H4c6; H4C8; H4C9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4K20; H4Lys20me3; H4M; his-20; his-22; his-4; his-52; his-54; his-8; HIST1H4; HIST1H4A; HIST1H4B; HIST1H4C; HIST1H4D; HIST1H4E; HIST1H4F; Hist1h4h; Hist1h4i; HIST1H4J; HIST1H4K; HIST1H4L; Hist1h4m; Hist2h4; HIST2H4A; HIST2H4B; Hist4h4; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1, H4a; histone cluster 1, H4b; histone cluster 1, H4e; histone cluster 1, H4i; histone cluster 2, H4; histone cluster 2, H4a; Histone Cluster 4; histone cluster 4, H4; histone family member; Histone H2B 2; Histone H4; Histone H4A; Histone H4K20me3; histone IV, family 2; K06C4.12; K06C4.4; methyl Histone 3; methyl Histone H3; T10C6.11; Trimethyl H4; Tri-methyl H4; Trimethyl Histone H4; Tri-methyl Histone H4; Tri-Methyl-H4 K20; Tri-Methyl-H4 Lys20; Tri-Methyl-Histone H4 K20; Tri-Methyl-Histone H4 Lys20; X04652
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 121504, 180072, 8294, 8359, 8363, 8366, 8367, 8370
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
H4K20me3
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
P62805, Q27894
Gene Symbols:
H4-16, H4C1, H4C11, H4C14, H4C2, H4C5, H4C9, his-4
Immunogen:
Synthetic peptide of Human Histone H4 (Immunogen sequence: 15-AKRHR(Kme3)VLRDN-25 (branched))
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
C. elegans, Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ChIP Assay, Dot Blot, ELISA, Western Blot
Clone:
6F8-D9
Conjugate:
Unconjugated
Gene:
H4C1
Gene Alias:
CELE_T10C6.11; F07B7.11; F07B7.4; F45F2.12; FO108; H4; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4 K20; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/j; H4/K; H4/M; H4/n; H4/O; H4/p; H4-12; H4-16; H4-53; H4C1; H4c11; H4C12; H4C13; H4c14; H4C15; H4C2; H4C3; H4C4; H4C5; H4c6; H4C8; H4C9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4K20; H4Lys20me3; H4M; his-20; his-22; his-4; his-52; his-54; his-8; HIST1H4; HIST1H4A; HIST1H4B; HIST1H4C; HIST1H4D; HIST1H4E; HIST1H4F; Hist1h4h; Hist1h4i; HIST1H4J; HIST1H4K; HIST1H4L; Hist1h4m; Hist2h4; HIST2H4A; HIST2H4B; Hist4h4; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1, H4a; histone cluster 1, H4b; histone cluster 1, H4e; histone cluster 1, H4i; histone cluster 2, H4; histone cluster 2, H4a; Histone Cluster 4; histone cluster 4, H4; histone family member; Histone H2B 2; Histone H4; Histone H4A; Histone H4K20me3; histone IV, family 2; K06C4.12; K06C4.4; methyl Histone 3; methyl Histone H3; T10C6.11; Trimethyl H4; Tri-methyl H4; Trimethyl Histone H4; Tri-methyl Histone H4; Tri-Methyl-H4 K20; Tri-Methyl-H4 Lys20; Tri-Methyl-Histone H4 K20; Tri-Methyl-Histone H4 Lys20; X04652
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
121504, 180072, 8294, 8359, 8363, 8366, 8367, 8370
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Nesprin 2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: Q8WXH0
Gene Symbols: SYNE2
Immunogen: Residues 1-459 of human Nesprin-2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b κ
Applications: Immunocytochemistry, Immunomicroscopy, Immunoprecipitation, Western Blot
Clone: K20-478-5
Conjugate: Unconjugated
Gene: SYNE2
Gene Alias: 6820443O06Rik; AW546258; D12Ertd777e; EDMD5; KASH domain-containing protein 2; KASH2; KIAA1011; MGC96690; mKIAA1011; Nesp2; Nesp2g; nesprin 2; nesprin-2; NUA; NUANCE; nuclear envelope spectrin repeat protein 2; Nucleus and actin connecting element protein; polytrophin; Protein NUANCE; spectrin repeat containing nuclear envelope protein 2; spectrin repeat containing, nuclear envelope 2; synaptic nuclear envelope 2; synaptic nuclear envelope protein 2; synaptic nuclei expressed gene 2; SYNE2; Syne-2; TROPH
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 23224
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Nesprin 2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
Q8WXH0
Gene Symbols:
SYNE2
Immunogen:
Residues 1-459 of human Nesprin-2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b κ
Applications:
Immunocytochemistry, Immunomicroscopy, Immunoprecipitation, Western Blot
Clone:
K20-478-5
Conjugate:
Unconjugated
Gene:
SYNE2
Gene Alias:
6820443O06Rik; AW546258; D12Ertd777e; EDMD5; KASH domain-containing protein 2; KASH2; KIAA1011; MGC96690; mKIAA1011; Nesp2; Nesp2g; nesprin 2; nesprin-2; NUA; NUANCE; nuclear envelope spectrin repeat protein 2; Nucleus and actin connecting element protein; polytrophin; Protein NUANCE; spectrin repeat containing nuclear envelope protein 2; spectrin repeat containing, nuclear envelope 2; synaptic nuclear envelope 2; synaptic nuclear envelope protein 2; synaptic nuclei expressed gene 2; SYNE2; Syne-2; TROPH
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
23224
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Emerin
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: P50402
Gene Symbols: Emd
Immunogen: Recombinant Human Emerin aa 1-188
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rabbit
Product Type: Antibody
Isotype: IgG1
Applications: Immunoblot, Immunocytochemistry, Western Blot
Clone: MANEM1(5D10)
Conjugate: Unconjugated
Gene: Emd
Gene Alias: AW550900; EDMD; EMD; Emerin; LEM domain containing 5; LEMD5; STA
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100328755, 2010
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Emerin
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
P50402
Gene Symbols:
Emd
Immunogen:
Recombinant Human Emerin aa 1-188
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rabbit
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunoblot, Immunocytochemistry, Western Blot
Clone:
MANEM1(5D10)
Conjugate:
Unconjugated
Gene:
Emd
Gene Alias:
AW550900; EDMD; EMD; Emerin; LEM domain containing 5; LEMD5; STA
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100328755, 2010
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid