PIMA518119

beta-2 Microglobulin Monoclonal Antibody (B2M-01), Alexa Fluor™ 647, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA518119-Each-of-1 In Stock ₹ 42,908.34

PIMA518119 - Each of 1

₹ 42,908.34

In Stock

Quantity

1

Base Price: ₹ 42,908.34

GST (18%): ₹ 7,723.501

Total Price: ₹ 50,631.841

Antigen

beta-2 Microglobulin

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 15mM sodium azide; pH 7.4

Gene Accession No.

P61769

Gene Symbols

B2m

Immunogen

Purified human beta2-microglobulin

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Flow Cytometry, Immunocytochemistry, Western Blot

Clone

B2M-01

Conjugate

Alexa Fluor 647

Gene

B2m

Gene Alias

B2m; B2-microglobulin; b2m-W01; b2m-W03; b2m-Z01; b2m-Z02; b2m-Z03; Beta 2 microglobin; Beta 2 microglobulin; beta 2-microglobulin; beta chain of MHC class I molecules; Beta2 microglobulin; beta-2 microglobulin; beta-2 microglobulin preprotein; beta2m; beta2-m; beta-2-microglobin; beta-2-microglobulin; beta-2-microglobulin C-terminal fragment (55 AA); Beta-2-microglobulin form pI 5.3; B-F; CDABP0092; HDCMA22P; IMD43; Lactollin; Ly-m11; MHC Class I; microglobulin beta-2; Orla-B2m

Host Species

Mouse

Purification Method

Size-exclusion chromatography

Regulatory Status

RUO

Gene ID (Entrez)

567

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

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Description

  • This antibody reacts with beta2-microglobulin associated with cell-surface MHC Class I molecules and other membrane antigens as well as with soluble beta2-microglobulin
  • It will not cross-react with mouse, rabbit, canine, chicken or bovine
  • Beta-2-microglobulin (B2M) is a 12-14 kDa protein that is a subunit of the major histocompatibility complex (MHC) class I
  • Human beta 2 Microglobulin associated with HLA Class I antigens are expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells, but is absent on erythrocytes
  • Beta-2 microglobulin is also found in free form in the plasma
  • The amino acid sequence of Beta-2-microglobulin is homologous to the constant regions of immunoglobulin heavy and light chains, with a predominantly beta pleated sheet structure
  • The protein is ubiquitously expressed in the cytoplasm, and is involved in antigen processing and presentation
  • Beta-2-microglobulin also plays a role in TCR signaling, and downstream signaling in naive CD8+ cells
  • Beta 2-microglobulin is encoded by the B2M gene located on chromosome 15
  • A mutation in the Beta-2-microglobulin gene has been shown to result in hypercatabolic hypoproteinemia
  • Levels of beta 2 microglobulin can be used to assess renal function in kidney transplant recipients
  • Beta-2-microglobulin that protein can be used as a prognostic marker for HIV infection.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA518119

--


Antigen:
beta-2 Microglobulin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P61769

Gene Symbols:
B2m

Immunogen:
Purified human beta2-microglobulin

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
B2M-01

Conjugate:
Alexa Fluor 647

Gene:
B2m

Gene Alias:
B2m; B2-microglobulin; b2m-W01; b2m-W03; b2m-Z01; b2m-Z02; b2m-Z03; Beta 2 microglobin; Beta 2 microglobulin; beta 2-microglobulin; beta chain of MHC class I molecules; Beta2 microglobulin; beta-2 microglobulin; beta-2 microglobulin preprotein; beta2m; beta2-m; beta-2-microglobin; beta-2-microglobulin; beta-2-microglobulin C-terminal fragment (55 AA); Beta-2-microglobulin form pI 5.3; B-F; CDABP0092; HDCMA22P; IMD43; Lactollin; Ly-m11; MHC Class I; microglobulin beta-2; Orla-B2m

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
567

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Thermo Scientific

PIMA518120

--


Antigen:
CD105

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P17813

Gene Symbols:
ENG

Immunogen:
Recombinant Vaccinia virus containing the human CD105 cDNA

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry, Western Blot

Clone:
MEM-226

Conjugate:
Alexa Fluor 488

Gene:
ENG

Gene Alias:
AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2022, 497010

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Thermo Scientific

PIMA518121

--


Antigen:
LAMP1

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P11279, P11438

Gene Symbols:
LAMP1

Immunogen:
Human PBMC

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
H4A3

Conjugate:
Alexa Fluor 488

Gene:
LAMP1

Gene Alias:
120 kDa lysosomal membrane glycoprotein; AI196048; CD107 antigen-like family member A; CD107a; I79_011073; Lamp I; LAMP1; LAMP-1; LAMPA; LGP120; LGP-120; LGPA; LGP-A; lysosomal associated membrane protein 1; Lysosomal associated membrane protein 1 (120 kDa); lysosomal membrane glycoprotein 1; lysosomal membrane glycoprotein A; lysosomal-associated membrane protein 1; lysosome-associated membrane glycoprotein 1; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 PRECURSOR (LAMP-1) (LGP-A) (LGP-120) (CD107A) (P2B); lysosome-associated membrane protein 1; P2B

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16783, 3916

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Thermo Scientific

PIMA518125

--


Antigen:
CD13

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P15144

Gene Symbols:
ANPEP

Immunogen:
Human AML cells

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
WM15

Conjugate:
Alexa Fluor 488

Gene:
ANPEP

Gene Alias:
alanyl (membrane) aminopeptidase; alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150); alanyl aminopeptidase; alanyl aminopeptidase, membrane; aminopeptidase; aminopeptidase Ey; Aminopeptidase M; aminopeptidase N; aminopeptidase N.; aminopeptidase N/CD13; Anpep; APDE; Apm; AP-M; APN; AP-N; bAPN; cAPN; Cd13; cluster of differentiation antigen 13 (CD13); fAPN; gp130; gp150; h AP-N; hAPN; kidney aminopeptidase M; kidney Zn peptidase; KZP; Lap1; Lap-1; leucine arylaminopeptidase 1; LOW QUALITY PROTEIN: aminopeptidase N; membrane alanine aminiopeptidase; membrane alanine aminopeptidase; membrane alanyl aminopeptidase; membrane protein p161; Microsomal aminopeptidase; myeloid plasma membrane glycoprotein CD13; p150; pAPN; PEPN; porcine aminopeptidase N; rAPN; rbAPN; Unknown (protein for MGC:126949)

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
290

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid