PIMA524403

DIO1 Monoclonal Antibody (1E4), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA524403-Each-of-1 In Stock ₹ 45,646.26

PIMA524403 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

DIO1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

Dio1

Gene Alias

5DI; D1; deiodinase, iodothyronine type I; deiodinase, iodothyronine, type I; Dio1; DIOI; hDido1; iodothyronine deiodinase type 1; ITDI1; thyroxine 5'-deiodinase; thyroxine deiodinase; thyroxine deiodinase type I (selenoprotein); thyroxine deiodinase, type I; TXDI1; Type 1 DI; type I iodothyronine deiodinase; Type-I 5'-deiodinase

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1733

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA

Clone

1E4

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

P49895

Gene Symbols

Dio1

Immunogen

DIO1 (NP_000783.2, 35 a.a. ∽ 125 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a κ

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Description

  • Peptide Sequence: DRVKRNILAM GEKTGMTRNP HFSHDNWIPT FFSTQYFWFV LKVRWQRLED TTELGGLAPN CPVVRLSGQR CNIWEFMQGN RPLVLNFGSC T The protein encoded by this gene is a thiol-requiring propylthiouracil-sensitive oxidoreductase
  • It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3)
  • It also degrades both hormones by inner ring deiodination (IRD)
  • Alternative splicing results in multiple transcript variants encoding different isoforms
  • Some, but not all, isoforms contain a selenocysteine (Sec) residue encoded by the UGA codon, which normally signals translation termination
  • The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal
  • Additional transcript variants have been described but are not supported by experimental evidence.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA524403

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Antigen:
DIO1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
Dio1

Gene Alias:
5DI; D1; deiodinase, iodothyronine type I; deiodinase, iodothyronine, type I; Dio1; DIOI; hDido1; iodothyronine deiodinase type 1; ITDI1; thyroxine 5'-deiodinase; thyroxine deiodinase; thyroxine deiodinase type I (selenoprotein); thyroxine deiodinase, type I; TXDI1; Type 1 DI; type I iodothyronine deiodinase; Type-I 5'-deiodinase

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1733

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA

Clone:
1E4

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
P49895

Gene Symbols:
Dio1

Immunogen:
DIO1 (NP_000783.2, 35 a.a. ∽ 125 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Thermo Scientific

PIMA524404

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Antigen:
PHC2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
Phc2

Gene Alias:
A3galt2; AA415044; D130050K19Rik; D4Ertd810e; early development regulator 2; early development regulator 2 (homolog of polyhomeotic 2); early development regulatory protein 2; Edr2; hPH2; mPH2; p36; Ph2; Phc2; polyhomeotic 2; polyhomeotic 2 protein; polyhomeotic homolog 2; polyhomeotic homolog 2 (Drosophila); polyhomeotic-like 2; polyhomeotic-like 2 (Drosophila); polyhomeotic-like protein 2

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1912

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
1F4

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
Q8IXK0

Gene Symbols:
Phc2

Immunogen:
PHC2 (NP_004418.2, 91 a.a. ∽ 200 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Thermo Scientific

PIMA524405

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Antigen:
EVC

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
Evc

Gene Alias:
DWF-1; Ellis van Creveld gene homolog; Ellis van Creveld gene syndrome; Ellis van Creveld protein; Ellis van Creveld syndrome; ellis-van Creveld syndrome protein; Ellis-van Creveld syndrome protein homolog; EVC; EvC ciliary complex subunit 1; EvC protein (Ellis-van Creveld syndrome); EVC1; EVCL

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2121

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
3C4

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
P57679

Gene Symbols:
Evc

Immunogen:
EVC (NP_055371, 493 a.a. ∽ 602 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Thermo Scientific

PIMA524408

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Antigen:
THAP12

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
THAP12

Gene Alias:
2900052B10Rik; 52 kDa repressor of the inhibitor of the protein kinase; 58 kDa interferon-induced protein kinase-interacting protein; DAP4; death-associated protein 4; inhibitor of protein kinase PKR; interferon-inducible, double stranded RNA dependent inhibitor, protein-kinase; P52rIPK; p58IPK-interacting protein; P58IPK-regulatory protein; PRKRIR; protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor); Rpkrir; testicular tissue protein Li 133; THAP domain containing 12; THAP domain-containing protein 0; THAP domain-containing protein 12; THAP0; THAP12

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5612

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA

Clone:
1C10-1A6

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
O43422

Gene Symbols:
THAP12

Immunogen:
PRKRIR (AAH21992, 1 a.a. ∽ 150 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ