PIMA524661
B-Raf (V600E) Recombinant Rabbit Monoclonal Antibody (RM8), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA524661-Each-of-1 | In Stock | ₹ 48,469.74 |
PIMA524661 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,469.74
GST (18%): ₹ 8,724.553
Total Price: ₹ 57,194.293
Antigen
B-Raf (V600E)
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH 7.2-7.4
Gene Accession No.
P15056
Gene Symbols
BRAF
Immunogen
Peptide corresponding to B-Raf V600E mutant.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
RM8
Conjugate
Unconjugated
Gene
BRAF
Gene Alias
94 kDa B-raf protein; 9930012E13Rik; AA120551; AA387315; AA473386; Braf; B-raf; B-raf protein; B-raf protein isoform 1; B-raf protein isoform 2; B-Raf proto-oncogene serine/threonine-protein kinase; B-Raf proto-oncogene serine/threonine-protein kinase (p94); B-Raf proto-oncogene, serine/threonine kinase; Braf transforming gene; BRAF1; B-RAF1; Braf2; Braf-2; C230098H17; C87398; C-RMIL; D6Ertd631e; FLJ95109; MGC126806; murine sarcoma viral (v-raf) oncogene homolog B1; NS7; p94; Proto-oncogene B-Raf; proto-oncogene c-Rmil; RAFB1; RMIL; rmil serine/threonine-protein kinase; serine/threonine kinase; serine/threonine-protein kinase B-raf; Serine/threonine-protein kinase Rmil; v-raf murine sarcoma viral oncogene homolog B; v-raf murine sarcoma viral oncogene homolog B1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
673
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- This antibody reacts to the BRAF V600E mutant
- No cross reactivity with wild type BRAF
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This gene, B-RAF/BRAF, encodes a protein belonging to the RAF family of serine/threonine protein kinases
- This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion
- Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung
- Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes
- A pseudogene of this gene has been identified on the X chromosome.
Compare Similar Items
Show Difference
Antigen: B-Raf (V600E)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH 7.2-7.4
Gene Accession No.: P15056
Gene Symbols: BRAF
Immunogen: Peptide corresponding to B-Raf V600E mutant.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: RM8
Conjugate: Unconjugated
Gene: BRAF
Gene Alias: 94 kDa B-raf protein; 9930012E13Rik; AA120551; AA387315; AA473386; Braf; B-raf; B-raf protein; B-raf protein isoform 1; B-raf protein isoform 2; B-Raf proto-oncogene serine/threonine-protein kinase; B-Raf proto-oncogene serine/threonine-protein kinase (p94); B-Raf proto-oncogene, serine/threonine kinase; Braf transforming gene; BRAF1; B-RAF1; Braf2; Braf-2; C230098H17; C87398; C-RMIL; D6Ertd631e; FLJ95109; MGC126806; murine sarcoma viral (v-raf) oncogene homolog B1; NS7; p94; Proto-oncogene B-Raf; proto-oncogene c-Rmil; RAFB1; RMIL; rmil serine/threonine-protein kinase; serine/threonine kinase; serine/threonine-protein kinase B-raf; Serine/threonine-protein kinase Rmil; v-raf murine sarcoma viral oncogene homolog B; v-raf murine sarcoma viral oncogene homolog B1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 673
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
B-Raf (V600E)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH 7.2-7.4
Gene Accession No.:
P15056
Gene Symbols:
BRAF
Immunogen:
Peptide corresponding to B-Raf V600E mutant.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
RM8
Conjugate:
Unconjugated
Gene:
BRAF
Gene Alias:
94 kDa B-raf protein; 9930012E13Rik; AA120551; AA387315; AA473386; Braf; B-raf; B-raf protein; B-raf protein isoform 1; B-raf protein isoform 2; B-Raf proto-oncogene serine/threonine-protein kinase; B-Raf proto-oncogene serine/threonine-protein kinase (p94); B-Raf proto-oncogene, serine/threonine kinase; Braf transforming gene; BRAF1; B-RAF1; Braf2; Braf-2; C230098H17; C87398; C-RMIL; D6Ertd631e; FLJ95109; MGC126806; murine sarcoma viral (v-raf) oncogene homolog B1; NS7; p94; Proto-oncogene B-Raf; proto-oncogene c-Rmil; RAFB1; RMIL; rmil serine/threonine-protein kinase; serine/threonine kinase; serine/threonine-protein kinase B-raf; Serine/threonine-protein kinase Rmil; v-raf murine sarcoma viral oncogene homolog B; v-raf murine sarcoma viral oncogene homolog B1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
673
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Histone H2A.X
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH 7.2-7.4
Gene Accession No.: P16104
Gene Symbols: H2AX
Immunogen: Peptide corresponding to the C-terminus of human Histone H2A.X.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Immunocytochemistry, Luminex, Western Blot
Clone: RM214
Conjugate: Unconjugated
Gene: H2AX
Gene Alias: AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2A.X; H2A.X variant histone; H2A/X; h2afx; H2ax; H2AX histone; Hist5-2ax; histone 5 protein 2ax; histone H2A.x; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3014
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Histone H2A.X
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH 7.2-7.4
Gene Accession No.:
P16104
Gene Symbols:
H2AX
Immunogen:
Peptide corresponding to the C-terminus of human Histone H2A.X.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Immunocytochemistry, Luminex, Western Blot
Clone:
RM214
Conjugate:
Unconjugated
Gene:
H2AX
Gene Alias:
AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2A.X; H2A.X variant histone; H2A/X; h2afx; H2ax; H2AX histone; Hist5-2ax; histone 5 protein 2ax; histone H2A.x; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3014
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: H2A.ZK7ac
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH 7.2-7.4
Gene Accession No.: P0C0S5, Q71UI9
Gene Symbols: H2AZ1, H2az2
Immunogen: Acetyl-peptide corresponding to Acetyl-Histone H2A.Z (Lys7).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ChIP Assay, ELISA, Immunocytochemistry, Luminex, Western Blot
Clone: RM222
Conjugate: Unconjugated
Gene: H2AZ1
Gene Alias: 11ac; Acetyl-Histone H2A.Z K7; Acetyl-Histone H2A.Z Lys7; H2A histone family member Z; H2A histone family, member Z; H2A.z; H2A.Z-1; H2A.ZK5; H2A.ZK5ac; H2A.ZLys7ac; H2A/z; H2AFZ; H2AFZac; H2AZ; H2AZ histone; H2AZK11ac; H2AZK7ac; H2AZLys7ac; histone H2A.Z
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3015, 94239
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
H2A.ZK7ac
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH 7.2-7.4
Gene Accession No.:
P0C0S5, Q71UI9
Gene Symbols:
H2AZ1, H2az2
Immunogen:
Acetyl-peptide corresponding to Acetyl-Histone H2A.Z (Lys7).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ChIP Assay, ELISA, Immunocytochemistry, Luminex, Western Blot
Clone:
RM222
Conjugate:
Unconjugated
Gene:
H2AZ1
Gene Alias:
11ac; Acetyl-Histone H2A.Z K7; Acetyl-Histone H2A.Z Lys7; H2A histone family member Z; H2A histone family, member Z; H2A.z; H2A.Z-1; H2A.ZK5; H2A.ZK5ac; H2A.ZLys7ac; H2A/z; H2AFZ; H2AFZac; H2AZ; H2AZ histone; H2AZK11ac; H2AZK7ac; H2AZLys7ac; histone H2A.Z
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3015, 94239
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Histone H2A.Z
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH 7.2-7.4
Gene Accession No.: P0C0S5, Q71UI9
Gene Symbols: H2AFZ, H2AZ1, H2az2
Immunogen: Peptide corresponding to the C-terminus of human Histone H2A.Z.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Immunocytochemistry, Luminex, Western Blot
Clone: RM215
Conjugate: Unconjugated
Gene: H2AZ1
Gene Alias: 11ac; C530002L11Rik; H2A histone family member V; H2A histone family member Z; H2A histone family member Z L homeolog; H2A histone family, member V; H2A histone family, member Va; H2A histone family, member Z; H2A.F/Z; H2A.z; H2A.Z variant histone 1; H2A.Z variant histone 2; H2A.Z variant histone 2a; H2A.Z1; H2a.z-1; H2A.Z-2; H2A.ZK5; H2A.ZK5ac; H2A.Zl; h2a.zl1; h2a.zl2; H2A/z; H2AF; H2AFV; h2afva; h2afz; h2afz.L; H2AFZac; H2AV; H2az; H2AZ histone; H2AZ1; H2AZ2; h2az2a; h2aza; H2AZK11ac; H2AZK7ac; histone (H2A.Z); histone H2A.F/Z; Histone H2A.V; Histone H2A.Z; histone H2A.Zl2; histone H2A.Z-like; histone variant H2A.F/Z; hypothetical protein; purine-rich binding element protein B; RCJMB04_2h11; Unknown (protein for MGC:133654); unnamed protein product; XELAEV_18005732mg; XH2AZ
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3015, 94239
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Histone H2A.Z
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH 7.2-7.4
Gene Accession No.:
P0C0S5, Q71UI9
Gene Symbols:
H2AFZ, H2AZ1, H2az2
Immunogen:
Peptide corresponding to the C-terminus of human Histone H2A.Z.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Immunocytochemistry, Luminex, Western Blot
Clone:
RM215
Conjugate:
Unconjugated
Gene:
H2AZ1
Gene Alias:
11ac; C530002L11Rik; H2A histone family member V; H2A histone family member Z; H2A histone family member Z L homeolog; H2A histone family, member V; H2A histone family, member Va; H2A histone family, member Z; H2A.F/Z; H2A.z; H2A.Z variant histone 1; H2A.Z variant histone 2; H2A.Z variant histone 2a; H2A.Z1; H2a.z-1; H2A.Z-2; H2A.ZK5; H2A.ZK5ac; H2A.Zl; h2a.zl1; h2a.zl2; H2A/z; H2AF; H2AFV; h2afva; h2afz; h2afz.L; H2AFZac; H2AV; H2az; H2AZ histone; H2AZ1; H2AZ2; h2az2a; h2aza; H2AZK11ac; H2AZK7ac; histone (H2A.Z); histone H2A.F/Z; Histone H2A.V; Histone H2A.Z; histone H2A.Zl2; histone H2A.Z-like; histone variant H2A.F/Z; hypothetical protein; purine-rich binding element protein B; RCJMB04_2h11; Unknown (protein for MGC:133654); unnamed protein product; XELAEV_18005732mg; XH2AZ
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3015, 94239
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid