PIMA524702
MCU Monoclonal Antibody (CL3576), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA524702-Each-of-1 | In Stock | ₹ 51,250.44 |
PIMA524702 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,250.44
GST (18%): ₹ 9,225.079
Total Price: ₹ 60,475.519
Antigen
MCU
Classification
Monoclonal
Concentration
1.00 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q8NE86
Gene Symbols
MCU
Immunogen
Recombinant Human MCU
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Western Blot
Clone
CL3576
Conjugate
Unconjugated
Gene
MCU
Gene Alias
2010012O16Rik; AV064928; C10orf42; Calcium uniporter protein, mitochondrial; Ccdc109a; coiled-coil domain containing 109A; coiled-coil domain-containing protein 109A; D130073L02Rik; Gm64; HsMCU; MCU; mitochondrial calcium uniporter
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
90550
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Immunogen sequence: TRQEYVYPEAR DRQYLLFFHK GAKKSRFDLE KYNQLKDAIA QAEMDLKRLR DPLQVHLPLR QIGE Binds to an epitope located within the peptide sequence RDRQYLLFFH as determined by overlapping synthetic peptides
- Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%
- Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria
- Constitutes the pore-forming and calcium-conducting subunit of the uniporter complex (uniplex)
- Activity is regulated by MICU1 and MICU2
- At low Ca(2+) levels MCU activity is down-regulated by MICU1 and MICU2; at higher Ca(2+) levels MICU1 increases MCU activity
- Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways
- Involved in buffering the amplitude of systolic calcium rises in cardiomyocytes
- While dispensable for baseline homeostatic cardiac function, acts as a key regulator of short-term mitochondrial calcium loading underlying a 'fight-or-flight' response during acute stress: acts by mediating a rapid increase of mitochondrial calcium in pacemaker cells
- participates in mitochondrial permeability transition during ischemia-reperfusion injury
- Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake
- Mitochondrial calcium uptake in skeletal muscle cells is involved in muscle size in adults
- Regulates synaptic vesicle endocytosis kinetics in central nerve terminal
- Involved in antigen processing and presentation.
Compare Similar Items
Show Difference
Antigen: MCU
Classification: Monoclonal
Concentration: 1.00 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8NE86
Gene Symbols: MCU
Immunogen: Recombinant Human MCU
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Western Blot
Clone: CL3576
Conjugate: Unconjugated
Gene: MCU
Gene Alias: 2010012O16Rik; AV064928; C10orf42; Calcium uniporter protein, mitochondrial; Ccdc109a; coiled-coil domain containing 109A; coiled-coil domain-containing protein 109A; D130073L02Rik; Gm64; HsMCU; MCU; mitochondrial calcium uniporter
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 90550
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
MCU
Classification:
Monoclonal
Concentration:
1.00 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8NE86
Gene Symbols:
MCU
Immunogen:
Recombinant Human MCU
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Western Blot
Clone:
CL3576
Conjugate:
Unconjugated
Gene:
MCU
Gene Alias:
2010012O16Rik; AV064928; C10orf42; Calcium uniporter protein, mitochondrial; Ccdc109a; coiled-coil domain containing 109A; coiled-coil domain-containing protein 109A; D130073L02Rik; Gm64; HsMCU; MCU; mitochondrial calcium uniporter
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
90550
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: ELTD1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9HBW9
Gene Symbols: ADGRL4
Immunogen: Recombinant Human ELTD1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry, Western Blot
Clone: CL4164
Conjugate: Unconjugated
Gene: ADGRL4
Gene Alias: 1110033N21Rik; ADGRL4; Adhesion G protein-coupled receptor L4; EGF, latrophilin and seven transmembrane domain containing 1; EGF, latrophilin and seven transmembrane domain-containing protein 1; EGF, latrophilin seven transmembrane domain containing 1; EGF, latrophilin seven transmembrane domain-containing protein 1; EGF,latrophilin and seven transmembrane domain-containing protein 1; EGF-TM7 receptor; EGF-TM7-latrophilin-related protein; Eltd1; ETL; ETL protein; ETL1; hCG_14667; KPG_003; UNQ202/PRO228
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 64123
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
ELTD1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9HBW9
Gene Symbols:
ADGRL4
Immunogen:
Recombinant Human ELTD1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry, Western Blot
Clone:
CL4164
Conjugate:
Unconjugated
Gene:
ADGRL4
Gene Alias:
1110033N21Rik; ADGRL4; Adhesion G protein-coupled receptor L4; EGF, latrophilin and seven transmembrane domain containing 1; EGF, latrophilin and seven transmembrane domain-containing protein 1; EGF, latrophilin seven transmembrane domain containing 1; EGF, latrophilin seven transmembrane domain-containing protein 1; EGF,latrophilin and seven transmembrane domain-containing protein 1; EGF-TM7 receptor; EGF-TM7-latrophilin-related protein; Eltd1; ETL; ETL protein; ETL1; hCG_14667; KPG_003; UNQ202/PRO228
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
64123
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: CT83
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q5H943
Gene Symbols: CT83
Immunogen: Recombinant Human CT83
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry, Western Blot
Clone: CL4762
Conjugate: Unconjugated
Gene: CT83
Gene Alias: Cancer/testis antigen 83; CT83; CXorf61; kita-kyushu lung cancer antigen 1; KKLC1; KK-LC-1
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 203413
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CT83
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q5H943
Gene Symbols:
CT83
Immunogen:
Recombinant Human CT83
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry, Western Blot
Clone:
CL4762
Conjugate:
Unconjugated
Gene:
CT83
Gene Alias:
Cancer/testis antigen 83; CT83; CXorf61; kita-kyushu lung cancer antigen 1; KKLC1; KK-LC-1
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
203413
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: RAB8A
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P35280, P55258, P61006
Gene Symbols: RAB8A
Immunogen: human RAB8A recombinant protein
Quantity: 400μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1 κ
Applications: Western Blot
Clone: 261CT1.3.1
Conjugate: Unconjugated
Gene: RAB8A
Gene Alias: AA409338; cell line NK14 derived transforming oncogene; MEL; mel transforming oncogene (derived from cell line NK14); mel transforming oncogene (derived from cell line NK14)- RAB8 homolog; mel transforming oncogene (RAB8 homolog); oncogene c-mel; Rab8; Rab8a; RAB8A, member RAS oncogene family; ras-associated protein RAB8; ras-related protein Rab-8A
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 117103, 17274, 4218
Content And Storage: -20°C
Form: Liquid
Antigen:
RAB8A
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P35280, P55258, P61006
Gene Symbols:
RAB8A
Immunogen:
human RAB8A recombinant protein
Quantity:
400μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
261CT1.3.1
Conjugate:
Unconjugated
Gene:
RAB8A
Gene Alias:
AA409338; cell line NK14 derived transforming oncogene; MEL; mel transforming oncogene (derived from cell line NK14); mel transforming oncogene (derived from cell line NK14)- RAB8 homolog; mel transforming oncogene (RAB8 homolog); oncogene c-mel; Rab8; Rab8a; RAB8A, member RAS oncogene family; ras-associated protein RAB8; ras-related protein Rab-8A
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
117103, 17274, 4218
Content And Storage:
-20°C
Form:
Liquid