PIMA524875

LSD1 Monoclonal Antibody (1E5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA524875-Each-of-1 In Stock ₹ 45,988.50

PIMA524875 - Each of 1

₹ 45,988.50

In Stock

Quantity

1

Base Price: ₹ 45,988.50

GST (18%): ₹ 8,277.93

Total Price: ₹ 54,266.43

Antigen

LSD1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

KDM1A

Gene Alias

1810043O07Rik; AA408884; amine oxidase (flavin containing) domain 2; AOF2; BHC110; BRAF35-HDAC complex protein BHC110; CPRF; D4Ertd478e; FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit; flavin-containing amine oxidase domain-containing protein 2; KDM1; KDM1A; KIAA0601; Lsd1; lysine (K)-specific demethylase 1; lysine (K)-specific demethylase 1A; lysine demethylase 1A; lysine-specific demethylase 1; lysine-specific histone demethylase 1; lysine-specific histone demethylase 1A; mKIAA0601; neuroprotective protein 3; RGD1562975; RP1-184J9.1; wu:fb82e06; wu:fc51a02; wu:fj36a05; wu:fj66b06

Host Species

Mouse

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23028

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

1E5

Formulation

0.1M tris glycine with 50% glycerol and 0.2% sodium azide; pH 7.4

Gene Accession No.

O60341

Gene Symbols

KDM1A

Immunogen

Purified recombinant human KDM1A protein fragments expressed in E.coli.

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG1

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Description

  • The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • LSD1 is a histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor
  • LSD1 contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain
  • This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase
  • It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed
  • LSD1 demethylates both mono- and tri-methylted 'Lys-4' of histone H3
  • This protein may play a role in the repression of neuronal genes
  • Alone, it is unable to demethylate H3 'Lys-4' on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity
  • It may also demethylate 'Lys-9' of histone H3, a specific tag for epigenetic transcriptional repression, thereby leading to derepression of androgen receptor target genes
  • Mutations affecting this gene can result in cleft palate, psychomotor retardation, and distintive facial features.

Compare Similar Items

Show Difference

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Thermo Scientific

PIMA524875

--


Antigen:
LSD1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
KDM1A

Gene Alias:
1810043O07Rik; AA408884; amine oxidase (flavin containing) domain 2; AOF2; BHC110; BRAF35-HDAC complex protein BHC110; CPRF; D4Ertd478e; FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit; flavin-containing amine oxidase domain-containing protein 2; KDM1; KDM1A; KIAA0601; Lsd1; lysine (K)-specific demethylase 1; lysine (K)-specific demethylase 1A; lysine demethylase 1A; lysine-specific demethylase 1; lysine-specific histone demethylase 1; lysine-specific histone demethylase 1A; mKIAA0601; neuroprotective protein 3; RGD1562975; RP1-184J9.1; wu:fb82e06; wu:fc51a02; wu:fj36a05; wu:fj66b06

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23028

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
1E5

Formulation:
0.1M tris glycine with 50% glycerol and 0.2% sodium azide; pH 7.4

Gene Accession No.:
O60341

Gene Symbols:
KDM1A

Immunogen:
Purified recombinant human KDM1A protein fragments expressed in E.coli.

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

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PIMA524878

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Antigen:
IdU

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
IdU

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
OTI7C9

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Iododeoxyuridine coupled to keyhole limpet hemocyanin.

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Chemical

Product Type:
Antibody

Isotype:
IgG2a

Img

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PIMA524881

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Antigen:
Hex

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
HHEX

Gene Alias:
hematopoietically expressed homeobox; hematopoietically expressed homeobox, related sequence 2; hematopoietically-expressed homeobox protein Hhex; HEX; Hex1; HHEX; Hhex-rs2; HMPH; homeobox; homeobox protein HEX; Homeobox protein PRH; homeobox, hematopoietically expressed; HOX11L-PEN; mHex; Prh; Prhx; proline-rich homeodomain-containing transcription factor

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3087

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
OTI3C4

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q03014

Gene Symbols:
HHEX

Immunogen:
Recombinant fragment expressed in E.coli corresponding to amino acids 100-270 of Hex.

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

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PIMA524884

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Antigen:
NTF4

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
NTF4

Gene Alias:
2900040K06Rik, AI462899, GLC10, GLC1O, neurotrophic factor 4, neurotrophic factor 5, neurotrophin 4, Neurotrophin 4/5, neurotrophin 5, Neurotrophin 5 (neurotrophin 4/5), neurotrophin 5 (neurotrophin 4/5), neurotrophin-4, Neurotrophin-5, neutrophic factor 4, Neutrophic factor 5, NT4, NT-4, NT4/5, NT-4/5, NT4/NT5, NT4P, NT5, NT-5, Ntf4, Ntf5, Ntf-5

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4909

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2E8

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P34130

Gene Symbols:
NTF4

Immunogen:
Human recombinant protein fragment corresponding to amino acids 81-210 human NT4 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1