PIMA524908

GAD67 Monoclonal Antibody (OTI3H2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA524908-Each-of-1 In Stock ₹ 50,180.94

PIMA524908 - Each of 1

₹ 50,180.94

In Stock

Quantity

1

Base Price: ₹ 50,180.94

GST (18%): ₹ 9,032.569

Total Price: ₹ 59,213.509

Antigen

GAD67

Classification

Monoclonal

Concentration

0.46 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

A0PA85, Q99259

Gene Symbols

GAD1

Immunogen

Full length human recombinant protein of GAD1 produced in HEK293T cell

Quantity

100μL

Primary or Secondary

Primary

Target Species

Canine, Human

Product Type

Antibody

Isotype

IgG2a

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

OTI3H2

Conjugate

Unconjugated

Gene

GAD1

Gene Alias

67 kDa glutamic acid decarboxylase; 67kDa glutamate decarboxylase 1; CPSQ1; EGK_04525; EP10; FLJ45882; GAD; GAD 1; GAD 67; GAD1; Gad-1; GAD25; GAD44; Gad67; GAD-67; Glutamate decarboxylase 1; Glutamate decarboxylase 1 (brain); glutamate decarboxylase 1 (brain, 67kDa); glutamate decarboxylase 1 isoform GAD67; glutamate decarboxylase 1 variant GAD67NT; glutamate decarboxylase 67 kDa isoform; GLUTAMATE DECARBOXYLASE, 67 KD ISOFORM (GAD-67) (67 KD GLUTAMIC ACID DECARBOXYLASE); glutamic acid decarboxylase; glutamic acid decarboxylase 1; glutamic acid decarboxylase isoform 67; OTTHUMP00000041055; SCP

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2571, 478794

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid
  • Although both GADs are found in the brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell
  • GAD-67 is responsible for the basal levels of GABA synthesis
  • In the case of a heightened demand for GABA in neurotransmission, GAD-65 will transiently activate to assist in GABA production
  • The loss of GAD-65 is detrimental and can impair GABA neurotransmission, however the loss of GAD-67 is lethal
  • Due to alternative splicing, two isoforms exist for GAD-67: the predominant GAD-67 form and the minor GAD-25 form.

Compare Similar Items

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Img

Thermo Scientific

PIMA524908

--


Antigen:
GAD67

Classification:
Monoclonal

Concentration:
0.46 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
A0PA85, Q99259

Gene Symbols:
GAD1

Immunogen:
Full length human recombinant protein of GAD1 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Canine, Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
OTI3H2

Conjugate:
Unconjugated

Gene:
GAD1

Gene Alias:
67 kDa glutamic acid decarboxylase; 67kDa glutamate decarboxylase 1; CPSQ1; EGK_04525; EP10; FLJ45882; GAD; GAD 1; GAD 67; GAD1; Gad-1; GAD25; GAD44; Gad67; GAD-67; Glutamate decarboxylase 1; Glutamate decarboxylase 1 (brain); glutamate decarboxylase 1 (brain, 67kDa); glutamate decarboxylase 1 isoform GAD67; glutamate decarboxylase 1 variant GAD67NT; glutamate decarboxylase 67 kDa isoform; GLUTAMATE DECARBOXYLASE, 67 KD ISOFORM (GAD-67) (67 KD GLUTAMIC ACID DECARBOXYLASE); glutamic acid decarboxylase; glutamic acid decarboxylase 1; glutamic acid decarboxylase isoform 67; OTTHUMP00000041055; SCP

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2571, 478794

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA524909

--


Antigen:
GAD67

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P18088, P48318, Q99259

Gene Symbols:
GAD1

Immunogen:
Full length human recombinant protein of GAD1 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
OTI3G9

Conjugate:
Unconjugated

Gene:
GAD1

Gene Alias:
67 kDa glutamic acid decarboxylase; 67kDa glutamate decarboxylase 1; CPSQ1; EGK_04525; EP10; FLJ45882; GAD; GAD 1; GAD 67; GAD1; Gad-1; GAD25; GAD44; Gad67; GAD-67; Glutamate decarboxylase 1; Glutamate decarboxylase 1 (brain); glutamate decarboxylase 1 (brain, 67kDa); glutamate decarboxylase 1 isoform GAD67; glutamate decarboxylase 1 variant GAD67NT; glutamate decarboxylase 67 kDa isoform; GLUTAMATE DECARBOXYLASE, 67 KD ISOFORM (GAD-67) (67 KD GLUTAMIC ACID DECARBOXYLASE); glutamic acid decarboxylase; glutamic acid decarboxylase 1; glutamic acid decarboxylase isoform 67; OTTHUMP00000041055; SCP

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14415, 24379, 2571

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA524911

--


Antigen:
NeuroG3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9Y4Z2

Gene Symbols:
NEUROG3

Immunogen:
Full-length protein expressed in 293T cell transfected with human NEUROG3 expression vector

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
OTI3B5

Conjugate:
Unconjugated

Gene:
NEUROG3

Gene Alias:
ATH4B; Atoh5; atonal homolog 5; BHLHA7; Class A basic helix-loop-helix protein 7; helix-loop-helix protein mATH-4B; LOW QUALITY PROTEIN: neurogenin-3; Math4B; Neurog3; neurogenin 3; Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B); neurogenin3; neurogenin-3; ngn3; NGN-3; Protein atonal homolog 5; Relax; transcriptional regulator, Relax

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
50674

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA524912

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Antigen:
Neurogenin 1

Classification:
Monoclonal

Concentration:
1.00 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q92886

Gene Symbols:
NEUROG1

Immunogen:
Full length human recombinant protein of NEUROG1 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Canine, Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
OTI8G8

Conjugate:
Unconjugated

Gene:
NEUROG1

Gene Alias:
AKA; ATH4C; basic helix-loop-helix transcription factor; bHLHa6; cb260; chunp6899; class A basic helix-loop-helix protein 6; Helix-loop-helix protein mATH-4C; Math4C; Neurod3; NEUROG1; Neurogenic basic-helix-loop-helix protein; neurogenic differentiation 3; neurogenic differentiation factor 3; neurogenin; neurogenin 1; neurogenin related protein-1; neurogenin-1; Neurogenin-related protein 1; NGN; Ngn1; NGN-1; ngr1; transcription factor; Zath4c; zNgn1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4762, 481516

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid