PIMA524916

TRPM4 Monoclonal Antibody (OTI14C3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA524916-Each-of-1 In Stock ₹ 50,352.06

PIMA524916 - Each of 1

₹ 50,352.06

In Stock

Quantity

1

Base Price: ₹ 50,352.06

GST (18%): ₹ 9,063.371

Total Price: ₹ 59,415.431

Antigen

TRPM4

Classification

Monoclonal

Concentration

0.7 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q8TD43

Gene Symbols

TRPM4

Immunogen

Full-length protein expressed in 293T cell transfected with human TRPM4 expression vector

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI14C3

Conjugate

Unconjugated

Gene

TRPM4

Gene Alias

1110030C19Rik; AW047689; Calcium-activated non-selective cation channel 1; H LTrpC-4; hTRPM4; Long transient receptor potential channel 4; LOW QUALITY PROTEIN: transient receptor potential cation channel subfamily M member 4; LTrpC4; LTrpC-4; melastatin like 2 protein; melastatin-4; Melastatin-like 2; MLS2s; PFHB1B; transient receptor potential cation channel subfamily M member 4; transient receptor potential cation channel, subfamily M, member 4; transient receptor potential ion channel melastatin subgroup member 4; Trpm4; TRPM4B

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

54795

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization
  • While it is activated by increase in intracellular Ca2+, it is impermeable to it
  • Mediates transport of monovalent cations (Na+, K+, Cs+, Li+), leading to depolarize the membrane
  • It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc
  • Participates in T-cell activation by modulating Ca2+ oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production
  • Involved in myogenic constriction of cerebral arteries
  • Controls insulin secretion in pancreatic beta-cells
  • May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca2+ overload
  • Affects T-helper 1 (Th1) and T-helper 2 (Th2) cell motility and cytokine production through differential regulation of calcium signaling and NFATC1 localization
  • Enhances cell proliferation through up-regulation of the beta-catenin signaling pathway.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA524916

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Antigen:
TRPM4

Classification:
Monoclonal

Concentration:
0.7 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q8TD43

Gene Symbols:
TRPM4

Immunogen:
Full-length protein expressed in 293T cell transfected with human TRPM4 expression vector

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI14C3

Conjugate:
Unconjugated

Gene:
TRPM4

Gene Alias:
1110030C19Rik; AW047689; Calcium-activated non-selective cation channel 1; H LTrpC-4; hTRPM4; Long transient receptor potential channel 4; LOW QUALITY PROTEIN: transient receptor potential cation channel subfamily M member 4; LTrpC4; LTrpC-4; melastatin like 2 protein; melastatin-4; Melastatin-like 2; MLS2s; PFHB1B; transient receptor potential cation channel subfamily M member 4; transient receptor potential cation channel, subfamily M, member 4; transient receptor potential ion channel melastatin subgroup member 4; Trpm4; TRPM4B

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54795

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA524917

--


Antigen:
SIGLEC9

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9Y336

Gene Symbols:
SIGLEC9

Immunogen:
Full length human recombinant protein of SIGLEC9 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI8F7

Conjugate:
Unconjugated

Gene:
SIGLEC9

Gene Alias:
Cd170; CD329; CDw329; FOAP-9; LOC100062855; LOC719831; MIS; mSiglec-E; Myeloid inhibitory siglec; OBBP-LIKE; Protein FOAP-9; sialic acid binding Ig like lectin 9; sialic acid binding Ig-like lectin 5; sialic acid binding Ig-like lectin 9; sialic acid binding Ig-like lectin E; sialic acid-binding Ig-like lectin 12; Sialic acid-binding Ig-like lectin 5; sialic acid-binding Ig-like lectin 9; Sialic acid-binding Ig-like lectin E; sialic acid-binding Ig-like lectin-like 1; sialic acid-binding immunoglobulin-like lectin E; Siglec; Siglec12; siglec-12; Siglec5; Siglec-5; SIGLEC9; siglec-9; Siglece; Siglec-E; Siglecl1; siglec-L1; SIGLEC-like 1; UNQ668/PRO1302

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27180

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA524918

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Antigen:
TRPM4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q8TD43

Gene Symbols:
TRPM4

Immunogen:
Full length human recombinant protein of TRPM4 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI10H5

Conjugate:
Unconjugated

Gene:
TRPM4

Gene Alias:
1110030C19Rik; AW047689; Calcium-activated non-selective cation channel 1; H LTrpC-4; hTRPM4; Long transient receptor potential channel 4; LOW QUALITY PROTEIN: transient receptor potential cation channel subfamily M member 4; LTrpC4; LTrpC-4; melastatin like 2 protein; melastatin-4; Melastatin-like 2; MLS2s; PFHB1B; transient receptor potential cation channel subfamily M member 4; transient receptor potential cation channel, subfamily M, member 4; transient receptor potential ion channel melastatin subgroup member 4; Trpm4; TRPM4B

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
484385, 54795

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA524920

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Antigen:
SSB

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P05455, P38656

Gene Symbols:
SSB

Immunogen:
Full-length protein expressed in 293T cell transfected with human SSB expression vector

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
OTI1E11

Conjugate:
Unconjugated

Gene:
SSB

Gene Alias:
autoantigen La; La; la autoantigen; La autoantigen homolog; La protein; la ribonucleoprotein; La ribonucleoprotein domain family, member 3; La/SSB; LARP3; lupus La antigen; lupus La protein; Lupus La protein homolog; Lupus LA protein homolog (LA ribonucleoprotein) (LA autoantigen homolog); lupus La protein-like; mRNA for autoantigen; OTTHUMP00000204777; sjoegren syndrome type B antigen; Sjogren syndrome antigen B; Sjogren syndrome antigen B (autoantigen La); small RNA binding exonuclease protection factor La; Ssb; SS-B; SS-B/La protein

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
478787, 6741, 81783

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid