PIMA524981

PRKAR1A Monoclonal Antibody (OTI6C7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA524981-Each-of-1 In Stock ₹ 53,303.88

PIMA524981 - Each of 1

₹ 53,303.88

In Stock

Quantity

1

Base Price: ₹ 53,303.88

GST (18%): ₹ 9,594.698

Total Price: ₹ 62,898.578

Antigen

PRKAR1A

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P10644, Q9DBC7

Gene Symbols

PRKAR1A

Immunogen

Full-length protein expressed in 293T cell transfected with human PRKAR1A expression vector

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI6C7

Conjugate

Unconjugated

Gene

PRKAR1A

Gene Alias

1300018C22Rik; ACRDYS1; ADOHR; cAMP-dependent protein kinase regulatory subunit RIalpha; cAMP-dependent protein kinase type I-alpha regulatory chain; cAMP-dependent protein kinase type I-alpha regulatory subunit; cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed; CAR; Carney complex type 1; CNC; CNC1; PKR1; PPNAD1; PRKAR1; Prkar1a; protein kinase A type 1a regulatory subunit; protein kinase cAMP-dependent type I regulatory subunit alpha; protein kinase, cAMP dependent regulatory, type 1, alpha; protein kinase, cAMP dependent regulatory, type I, alpha; protein kinase, cAMP-dependent, regulatory subunit type I alpha; protein kinase, cAMP-dependent, regulatory, type I, alpha; RIalpha; RIIA; Tissue-specific extinguisher 1; Tse1; Tse-1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19084, 5573

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • cAMP is a signaling molecule important for a variety of cellular functions
  • cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins
  • The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits
  • cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits
  • Four different regulatory subunits and three catalytic subunits have been identified in humans
  • This gene encodes one of the regulatory subunits
  • This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids
  • Mutations in this gene cause Carney complex (CNC)
  • This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2
  • A nonconventional nuclear localization sequence (NLS) has been found for this protein which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40)
  • Three alternatively spliced transcript variants encoding the same protein have been observed.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA524981

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Antigen:
PRKAR1A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P10644, Q9DBC7

Gene Symbols:
PRKAR1A

Immunogen:
Full-length protein expressed in 293T cell transfected with human PRKAR1A expression vector

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI6C7

Conjugate:
Unconjugated

Gene:
PRKAR1A

Gene Alias:
1300018C22Rik; ACRDYS1; ADOHR; cAMP-dependent protein kinase regulatory subunit RIalpha; cAMP-dependent protein kinase type I-alpha regulatory chain; cAMP-dependent protein kinase type I-alpha regulatory subunit; cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed; CAR; Carney complex type 1; CNC; CNC1; PKR1; PPNAD1; PRKAR1; Prkar1a; protein kinase A type 1a regulatory subunit; protein kinase cAMP-dependent type I regulatory subunit alpha; protein kinase, cAMP dependent regulatory, type 1, alpha; protein kinase, cAMP dependent regulatory, type I, alpha; protein kinase, cAMP-dependent, regulatory subunit type I alpha; protein kinase, cAMP-dependent, regulatory, type I, alpha; RIalpha; RIIA; Tissue-specific extinguisher 1; Tse1; Tse-1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19084, 5573

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA524983

--


Antigen:
XRCC4

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q13426, Q924T3

Gene Symbols:
XRCC4

Immunogen:
Full-length protein expressed in 293T cell transfected with human XRCC4 expression vector

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4H9

Conjugate:
Unconjugated

Gene:
XRCC4

Gene Alias:
2310057B22Rik; AW413319; AW545101; DNA repair protein XRCC4; SSMED; X-ray repair complementing defective repair in Chinese hamster cells 4; X-ray repair cross complementing 4; X-ray repair cross complementing protein 4; X-ray repair cross-complementing protein 4; XRCC4

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
108138, 7518

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA524987

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Antigen:
LTA4H

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P09960

Gene Symbols:
LTA4H

Immunogen:
Full-length protein expressed in 293T cell transfected with human LTA4H expression vector

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
OTI2A9

Conjugate:
Unconjugated

Gene:
LTA4H

Gene Alias:
Leukotriene A(4) hydrolase; leukotriene A4 hydrolase; Leukotriene A-4 hydrolase; LKHA4; LTA4; LTA4 hydrodase; LTA-4 hydrolase; LTA4H; testicular secretory protein Li 27

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4048

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA524988

--


Antigen:
ILF2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q12905

Gene Symbols:
ILF2

Immunogen:
Full-length protein expressed in 293T cell transfected with human ILF2 expression vector

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Canine, Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI6F1

Conjugate:
Unconjugated

Gene:
ILF2

Gene Alias:
6230405A16Rik; Ab1-143; ILF2; interleukin enhancer binding factor 2; interleukin enhancer binding factor 2, 45kD; interleukin enhancer binding factor 2, 45kDa; interleukin enhancer-binding factor 2; Interleukin enhancer-binding factor 2 homolog; liver regeneration-related protein LRRG031; MGC8391; Nf45; nuclear factor of activated T-cells 45 kDa; nuclear factor of activated T-cells, 45-kDa; PRO3063; TEG-267; testis expressed gene 267; Tex261; Tex267; Unknown (protein for MGC:134524); wu:fb34h01; zgc:73084; zgc:77276

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3608, 480139

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid