PIMA525621

GATM Monoclonal Antibody (OTI1E3), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA525621-Each-of-1 In Stock ₹ 50,266.50

PIMA525621 - Each of 1

₹ 50,266.50

In Stock

Quantity

1

Base Price: ₹ 50,266.50

GST (18%): ₹ 9,047.97

Total Price: ₹ 59,314.47

Antigen

GATM

Classification

Monoclonal

Concentration

0.95 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P50440

Gene Symbols

GATM

Immunogen

Full length human recombinant protein of GATM produced in HEK293T cell

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI1E3

Conjugate

Unconjugated

Gene

GATM

Gene Alias

1810003P21Rik; Agat; AI314789; AT; CCDS3; GATM; glycine amidinotransferase; glycine amidinotransferase (L-arginine:glycine amidinotransferase); glycine amidinotransferase, mitochondrial; L-arginine: glycine amidinotransferase; l-arginine:glycine amidinotransferase; testicular secretory protein Li 19; transamidinase

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2628

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • AGAT, also known as glycine amidinotransferase (L-arginine:glycine amidinotransferase), GATM or transamidinase, is a 423 amino acid protein belonging to the amidinotransferase family
  • Encoded by a gene that maps to human chromosome 15q21.1, AGAT exists as three alternatively spliced isoforms and consists of a homodimer, with equilibrium between monomeric and dimeric forms favoring a monomer subunit structure
  • AGAT localizes to mitochondrial inner membranes, peripheral membranes and cytoplasm
  • Biallelically expressed in placenta and fetal tissues, AGAT is also expressed in brain, heart, liver, lung, salivary gland and skeletal muscle tissue, with high expression in kidney
  • AGAT is elevated in the myocardium during heart failure and is decreased in inter-uterine growth restriction (IUGR)-associated placenta
  • AGAT catalyzes biosynthesis of guanidinoacetate, the immediate precursor of creatine, which plays a vital role in energy metabolism in muscle tissues
  • AGAT defects are associated with arginine:glycine amidinotransferase deficiency, an autosomal recessive disorder characterized by developmental delay or regression, mental retardation, severe disturbance of expressive and cognitive speech and severe depletion of creatine/phosphocreatine in brain
  • AGAT may be linked to embryonic and central nervous system development and may function in heart failure response by elevating local creatine synthesis.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA525621

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Antigen:
GATM

Classification:
Monoclonal

Concentration:
0.95 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P50440

Gene Symbols:
GATM

Immunogen:
Full length human recombinant protein of GATM produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1E3

Conjugate:
Unconjugated

Gene:
GATM

Gene Alias:
1810003P21Rik; Agat; AI314789; AT; CCDS3; GATM; glycine amidinotransferase; glycine amidinotransferase (L-arginine:glycine amidinotransferase); glycine amidinotransferase, mitochondrial; L-arginine: glycine amidinotransferase; l-arginine:glycine amidinotransferase; testicular secretory protein Li 19; transamidinase

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2628

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA525624

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Antigen:
PSMD2

Classification:
Monoclonal

Concentration:
0.7 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q13200, Q4FZT9, Q8VDM4

Gene Symbols:
PSMD2

Immunogen:
Full length human recombinant protein of PSMD2 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1G6

Conjugate:
Unconjugated

Gene:
PSMD2

Gene Alias:
26S proteasome non-ATPase regulatory subunit 2; 26S proteasome non-ATPase regulatory subunit 2-like protein; 26S proteasome regulatory subunit RPN1; 26S proteasome regulatory subunit S2; 26S proteasome subunit p97; 55.11 protein; 9430095H01Rik; AA407121; F23F1.8; I79_017809; MGC14274; P97; proteasome (prosome, macropain) 26S subunit, non-ATPase, 2; proteasome 26S subunit, non-ATPase 2; protein 55.11; PSMD2; RPN1; S2; TEG-190; testis expressed gene 190; Tex190; TNFR-associated protein 2; TRAP2; Tumor necrosis factor type 1 receptor-associated protein 2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21762, 287984, 478654, 5708

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA525625

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Antigen:
TOMM34

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q15785

Gene Symbols:
Tomm34

Immunogen:
Full length human recombinant protein of TOMM34 produced in HEK293 cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
OTI2A6

Conjugate:
Unconjugated

Gene:
Tomm34

Gene Alias:
2610100K07Rik; hTom34; HTOM34P; mitochondrial import receptor subunit TOM34; outer mitochondrial membrane translocase (34kD); TOM34; Tomm34; Translocase of outer membrane 34 kDa subunit; translocase of outer mitochondrial membrane 34; URCC3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10953

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA525626

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Antigen:
CBR3

Classification:
Monoclonal

Concentration:
0.43 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O75828, Q8K354

Gene Symbols:
CBR3

Immunogen:
Full length human recombinant protein of CBR3 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1G6

Conjugate:
Unconjugated

Gene:
CBR3

Gene Alias:
1110001J05Rik; C81353; carbonyl reductase (NADPH) 3; carbonyl reductase [NADPH] 3; carbonyl reductase 3; Cbr3; epididymis secretory protein Li 25; hCBR3; HEL-S-25; NADPH-dependent carbonyl reductase 3; SDR21C2; Short chain dehydrogenase/reductase family 21C member 2; short chain dehydrogenase/reductase family 21C, member 2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
109857, 304078, 487748, 874

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid