PIMA525732
PDE6 gamma Monoclonal Antibody (OTI2F5), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA525732-Each-of-1 | In Stock | ₹ 50,180.94 |
PIMA525732 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,180.94
GST (18%): ₹ 9,032.569
Total Price: ₹ 59,213.509
Antigen
PDE6 gamma
Classification
Monoclonal
Concentration
0.72 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P18545
Gene Symbols
PDE6G
Immunogen
Full length human recombinant protein of PDE6G produced in HEK293T cell
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI2F5
Conjugate
Unconjugated
Gene
PDE6G
Gene Alias
GMP-PDE gamma; p3AT; PDE6G; PDEG; phosphodiesterase 6G; phosphodiesterase 6G, cGMP-specific, rod, gamma; phosphodiesterase, cyclic GMP (rod receptor), gamma polypeptide; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; rod cG-PDE G; RP57; unnamed protein product
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5148
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- The second messengers cAMP and cGMP are key regulatory molecules that are involved in a wide variety of signal transduction pathways
- Levels of cAMP and cGMP are regulated by their rate of synthesis by nucleotide cyclases and by their rate of hydrolysis by cyclic nucleotide phosphodiesterases (PDEs)
- PDEs form a superfamily of enzymes that catalyze the conversion of 3-prime, 5-prime-cyclic nucleotides to the corresponding nucleoside 5-prime-monophosphates
- PDE6 is the effector enzyme in the G protein-mediated signal transduction cascade in the visual system
- There are five different subunits consisting of rod and cone specific catalytic subunits: alpha' (Cone), alpha (Rod), and beta (Rod), the inhibitory subunit gamma, and subunit delta of unknown function (which likely interacts with many other proteins besides the PDE6 family)
- The catalytic core of the PDE6 system is comprised of alpha'/alpha' homodimers in the cone and alpha/beta heterodimers in the rod
- The C-terminus of both the catalytic and inhibitory subunits is modified by methylation, myristyolation and prenylation which have been shown to be critical for proper complex assembly and membrane association.
Compare Similar Items
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Antigen: PDE6 gamma
Classification: Monoclonal
Concentration: 0.72 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P18545
Gene Symbols: PDE6G
Immunogen: Full length human recombinant protein of PDE6G produced in HEK293T cell
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI2F5
Conjugate: Unconjugated
Gene: PDE6G
Gene Alias: GMP-PDE gamma; p3AT; PDE6G; PDEG; phosphodiesterase 6G; phosphodiesterase 6G, cGMP-specific, rod, gamma; phosphodiesterase, cyclic GMP (rod receptor), gamma polypeptide; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; rod cG-PDE G; RP57; unnamed protein product
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5148
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
PDE6 gamma
Classification:
Monoclonal
Concentration:
0.72 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P18545
Gene Symbols:
PDE6G
Immunogen:
Full length human recombinant protein of PDE6G produced in HEK293T cell
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2F5
Conjugate:
Unconjugated
Gene:
PDE6G
Gene Alias:
GMP-PDE gamma; p3AT; PDE6G; PDEG; phosphodiesterase 6G; phosphodiesterase 6G, cGMP-specific, rod, gamma; phosphodiesterase, cyclic GMP (rod receptor), gamma polypeptide; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; rod cG-PDE G; RP57; unnamed protein product
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5148
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: NUBPL
Classification: Monoclonal
Concentration: 1.1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q8TB37
Gene Symbols: Nubpl
Immunogen: Human recombinant protein fragment corresponding to amino acids 1-250 of NUBPL produced in HEK293T cell
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: OTI5D5
Conjugate: Unconjugated
Gene: Nubpl
Gene Alias: 2410170E07Rik; C14orf127; huInd1; IND1; IND1 homolog; Iron-sulfur protein NUBPL; iron-sulfur protein required for NADH dehydrogenase; NUBPL; nucleotide binding protein like; nucleotide binding protein-like; nucleotide-binding protein-like; RGD1307232
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 80224
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
NUBPL
Classification:
Monoclonal
Concentration:
1.1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q8TB37
Gene Symbols:
Nubpl
Immunogen:
Human recombinant protein fragment corresponding to amino acids 1-250 of NUBPL produced in HEK293T cell
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI5D5
Conjugate:
Unconjugated
Gene:
Nubpl
Gene Alias:
2410170E07Rik; C14orf127; huInd1; IND1; IND1 homolog; Iron-sulfur protein NUBPL; iron-sulfur protein required for NADH dehydrogenase; NUBPL; nucleotide binding protein like; nucleotide binding protein-like; nucleotide-binding protein-like; RGD1307232
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
80224
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: UNG
Classification: Monoclonal
Concentration: 0.3 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P13051
Gene Symbols: Ung
Immunogen: Full length human recombinant protein of UNG produced in HEK293T cell
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG2b
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI1G2
Conjugate: Unconjugated
Gene: Ung
Gene Alias: DGU; DKFZp781L1143; HIGM4; HIGM5; UDG; UNG; Ung1; UNG15; UNG2; unga; uracil DNA glycosylase; uracil DNA glycosylase a; uracil-DNA glycosylase; uracil-DNA glycosylase 1, uracil-DNA glycosylase 2; uracil-DNA glycosylase isoform UNG1; uracil-DNA glycosylase isoform UNG2; uracil-DNA glycosylase nuclear isoform; zgc:56102
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7374
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
UNG
Classification:
Monoclonal
Concentration:
0.3 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P13051
Gene Symbols:
Ung
Immunogen:
Full length human recombinant protein of UNG produced in HEK293T cell
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI1G2
Conjugate:
Unconjugated
Gene:
Ung
Gene Alias:
DGU; DKFZp781L1143; HIGM4; HIGM5; UDG; UNG; Ung1; UNG15; UNG2; unga; uracil DNA glycosylase; uracil DNA glycosylase a; uracil-DNA glycosylase; uracil-DNA glycosylase 1, uracil-DNA glycosylase 2; uracil-DNA glycosylase isoform UNG1; uracil-DNA glycosylase isoform UNG2; uracil-DNA glycosylase nuclear isoform; zgc:56102
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7374
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: UBE2M
Classification: Monoclonal
Concentration: 0.69 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P61081, P61082
Gene Symbols: UBE2M
Immunogen: Full length human recombinant protein of UBE2M produced in HEK293T cell
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse, Non-human Primate
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Western Blot
Clone: OTI2D9
Conjugate: Unconjugated
Gene: UBE2M
Gene Alias: 2510040H03Rik; EGK_11185; hUbc12; NEDD8 carrier protein; NEDD8 protein ligase; NEDD8-conjugating enzyme Ubc12; UBC12; UBC12 homolog, yeast; UBC-RS2; Ube2m; ubiquitin C, related sequence 2; ubiquitin carrier protein M; ubiquitin conjugating enzyme E2 M; ubiquitin conjugating enzyme E2M; Ubiquitin-conjugating enzyme E2 M; ubiquitin-conjugating enzyme E2M; ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast); ubiquitin-protein ligase M; yeast UBC12 homolog
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22192, 484221, 9040
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
UBE2M
Classification:
Monoclonal
Concentration:
0.69 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P61081, P61082
Gene Symbols:
UBE2M
Immunogen:
Full length human recombinant protein of UBE2M produced in HEK293T cell
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse, Non-human Primate
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Western Blot
Clone:
OTI2D9
Conjugate:
Unconjugated
Gene:
UBE2M
Gene Alias:
2510040H03Rik; EGK_11185; hUbc12; NEDD8 carrier protein; NEDD8 protein ligase; NEDD8-conjugating enzyme Ubc12; UBC12; UBC12 homolog, yeast; UBC-RS2; Ube2m; ubiquitin C, related sequence 2; ubiquitin carrier protein M; ubiquitin conjugating enzyme E2 M; ubiquitin conjugating enzyme E2M; Ubiquitin-conjugating enzyme E2 M; ubiquitin-conjugating enzyme E2M; ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast); ubiquitin-protein ligase M; yeast UBC12 homolog
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22192, 484221, 9040
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid