PIMA525868

RUVBL2 Monoclonal Antibody (OTI1A6), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA525868-Each-of-1 In Stock ₹ 50,266.50

PIMA525868 - Each of 1

₹ 50,266.50

In Stock

Quantity

1

Base Price: ₹ 50,266.50

GST (18%): ₹ 9,047.97

Total Price: ₹ 59,314.47

Antigen

RUVBL2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q9WTM5, Q9Y230

Gene Symbols

Ruvbl2

Immunogen

Human recombinant protein fragment corresponding to amino acids 113-370 of RUVBL2 produced in E.coli

Quantity

100μL

Primary or Secondary

Primary

Target Species

Canine, Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI1A6

Conjugate

Unconjugated

Gene

Ruvbl2

Gene Alias

48 kDa TATA box-binding protein-interacting protein; 48 kDa TBP-interacting protein; 51 kDa erythrocyte cytosolic protein; CGI-46; ECP51; ECP-51; erythrocyte cytosolic protein, 51-KD; INO80 complex subunit J; INO80J; liebeskummer; lik; mp47; p47; p47 protein; Repressing pontin 52; reptin; Reptin 52; reptin52 protein; RuvB (E coli homolog)-like 2; RuvB like AAA ATPase 2; RuvB like AAA ATPase 2 S homeolog; ruvbl2; RUVBL2 protein; ruvbl2.S; ruvB-like 2; RuvB-like AAA ATPase 2; RuvB-like DNA helicase reptin; RuvB-like protein 2; RVB2; TAP54-beta; TIH2; TIP48; TIP49B; TIP60-associated protein 54-beta; wu:fi25f01; XELAEV_180378471mg; xReptin; zReptin

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10856, 20174, 292907, 476418

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Description

  • Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (5' to 3') activity
  • Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A
  • This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription
  • This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair
  • The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400
  • NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage
  • RUVBL2 plays an essential role in oncogenic transformation by MYC and also modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex
  • May also inhibit the transcriptional activity of ATF2.

Compare Similar Items

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Img

Thermo Scientific

PIMA525868

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Antigen:
RUVBL2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9WTM5, Q9Y230

Gene Symbols:
Ruvbl2

Immunogen:
Human recombinant protein fragment corresponding to amino acids 113-370 of RUVBL2 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1A6

Conjugate:
Unconjugated

Gene:
Ruvbl2

Gene Alias:
48 kDa TATA box-binding protein-interacting protein; 48 kDa TBP-interacting protein; 51 kDa erythrocyte cytosolic protein; CGI-46; ECP51; ECP-51; erythrocyte cytosolic protein, 51-KD; INO80 complex subunit J; INO80J; liebeskummer; lik; mp47; p47; p47 protein; Repressing pontin 52; reptin; Reptin 52; reptin52 protein; RuvB (E coli homolog)-like 2; RuvB like AAA ATPase 2; RuvB like AAA ATPase 2 S homeolog; ruvbl2; RUVBL2 protein; ruvbl2.S; ruvB-like 2; RuvB-like AAA ATPase 2; RuvB-like DNA helicase reptin; RuvB-like protein 2; RVB2; TAP54-beta; TIH2; TIP48; TIP49B; TIP60-associated protein 54-beta; wu:fi25f01; XELAEV_180378471mg; xReptin; zReptin

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10856, 20174, 292907, 476418

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA525871

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Antigen:
Epsin 2

Classification:
Monoclonal

Concentration:
0.96 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O95208, Q9Z1Z3

Gene Symbols:
EPN2

Immunogen:
Full length human recombinant protein of EPN2 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1C2

Conjugate:
Unconjugated

Gene:
EPN2

Gene Alias:
9530051D10Rik; AA536924; EH domain binding protein epsin 2; EHB21; EPN2; Eps15 binding protein; EPS-15-interacting protein 2; epsin 2; epsin-2; Ibp2; Intersectin-EH-binding protein 2; KIAA1065

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22905, 60443

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA525874

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Antigen:
GADD34

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O75807, P17564, Q6IN02

Gene Symbols:
PPP1R15A

Immunogen:
Full length human recombinant protein of PPP1R15A produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3D12

Conjugate:
Unconjugated

Gene:
PPP1R15A

Gene Alias:
9630030H21; Gadd34; growth arrest and DNA damage-inducible protein GADD34; growth arrest and DNA-damage-inducible 34; Myd116; myeloid differentiation primary response gene 116; myeloid differentiation primary response protein MyD116; Myeloid differentiation primary response protein MyD116 homolog; Peg3; PEG-3; PPP1R15A; PR15A; Progression elevated gene 3 protein; protein phosphatase 1 regulatory subunit 15A; protein phosphatase 1, regulatory (inhibitor) subunit 15A; protein phosphatase 1, regulatory subunit 15A; RGD1624209

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171071, 17872, 23645, 476419

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA525875

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Antigen:
GADD34

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O75807

Gene Symbols:
PPP1R15A

Immunogen:
Full length human recombinant protein of PPP1R15A produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4F1

Conjugate:
Unconjugated

Gene:
PPP1R15A

Gene Alias:
9630030H21; Gadd34; growth arrest and DNA damage-inducible protein GADD34; growth arrest and DNA-damage-inducible 34; Myd116; myeloid differentiation primary response gene 116; myeloid differentiation primary response protein MyD116; Myeloid differentiation primary response protein MyD116 homolog; Peg3; PEG-3; PPP1R15A; PR15A; Progression elevated gene 3 protein; protein phosphatase 1 regulatory subunit 15A; protein phosphatase 1, regulatory (inhibitor) subunit 15A; protein phosphatase 1, regulatory subunit 15A; RGD1624209

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23645

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid