PIMA525946

RYBP Monoclonal Antibody (OTI2B4), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA525946-Each-of-1 In Stock ₹ 50,180.94

PIMA525946 - Each of 1

₹ 50,180.94

In Stock

Quantity

1

Base Price: ₹ 50,180.94

GST (18%): ₹ 9,032.569

Total Price: ₹ 59,213.509

Antigen

RYBP

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q8CCI5, Q8N488

Gene Symbols

Rybp

Immunogen

Full length human recombinant protein of RYBP produced in E.coli

Quantity

100μL

Primary or Secondary

Primary

Target Species

Canine, Human, Mouse, Non-human Primate

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI2B4

Conjugate

Unconjugated

Gene

Rybp

Gene Alias

2410018J24Rik; AAP1; APAP-1; apoptin-associating protein 1; Death effector domain-associated factor; DEDAF; DED-associated factor; RING1 and YY1 binding protein; RING1 and YY1-binding protein; ring1 interactor RYBP; Rybp; YEAF1; YY1 and E4TF1 associated factor 1; YY1 and E4TF1-associated factor 1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23429, 484690, 56353

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • RYBP involves component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development
  • PcG PRC1-like complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility
  • Component of a PRC1-like complex that mediates monoubiquitination of histone H2A 'Lys-119' on the X chromosome and is required for normal silencing of one copy of the X chromosome in XX females
  • May stimulate ubiquitination of histone H2A 'Lys-119' by recruiting the complex to target sites
  • Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes
  • May also regulate the ubiquitin-mediated proteasomal degradation of other proteins like FANK1 to regulate apoptosis
  • May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1
  • May bind to DNA
  • May play a role in the repression of tumor growth and metastasis in breast cancer by down-regulating SRRM3.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA525946

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Antigen:
RYBP

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q8CCI5, Q8N488

Gene Symbols:
Rybp

Immunogen:
Full length human recombinant protein of RYBP produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI2B4

Conjugate:
Unconjugated

Gene:
Rybp

Gene Alias:
2410018J24Rik; AAP1; APAP-1; apoptin-associating protein 1; Death effector domain-associated factor; DEDAF; DED-associated factor; RING1 and YY1 binding protein; RING1 and YY1-binding protein; ring1 interactor RYBP; Rybp; YEAF1; YY1 and E4TF1 associated factor 1; YY1 and E4TF1-associated factor 1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23429, 484690, 56353

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA525947

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Antigen:
CRYZL1

Classification:
Monoclonal

Concentration:
1.08 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O95825

Gene Symbols:
CRYZL1

Immunogen:
Full length human recombinant protein of CRYZL1 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2F9

Conjugate:
Unconjugated

Gene:
CRYZL1

Gene Alias:
2210407J23Rik; 2410006O11Rik; 4P11; crystallin zeta like 1; crystallin, zeta (quinone reductase)-like 1; crystallin, zeta like 1; crystallin, zeta-like 1 isoform a; Cryzl1; dZ63M10.5; protein 4P11; QOH-1; quinone oxidoreductase homolog 1; Quinone oxidoreductase-like protein 1; quinone oxidoreductase-like protein 1; LOW QUALITY PROTEIN: quinone oxidoreductase-like protein 1; quinone reductase-like 1; zeta-crystallin homolog; zgc:92225

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9946

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA525948

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Antigen:
SCFD1

Classification:
Monoclonal

Concentration:
0.87 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q62991, Q8WVM8

Gene Symbols:
SCFD1

Immunogen:
Full length human recombinant protein of SCFD1 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2E7

Conjugate:
Unconjugated

Gene:
SCFD1

Gene Alias:
3110021P21Rik; C14orf163; FKSG23; KIAA0917; Ra410; rSly1; Scfd1; Sec1 family domain containing 1; sec1 family domain-containing protein 1; Sly1; SLY1 homolog; Sly1p; STXBP1L2; Syntaxin-binding protein 1-like 2; vesicle transport-related protein; vesicle transport-related protein Ra410

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23256, 480281, 54350

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA525950

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Antigen:
UBE2E3

Classification:
Monoclonal

Concentration:
0.76 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q969T4

Gene Symbols:
UBE2E3

Immunogen:
Full length human recombinant protein of UBE2E3 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4B4

Conjugate:
Unconjugated

Gene:
UBE2E3

Gene Alias:
E2 ubiquitin-conjugating enzyme E3; Ubce4; UBCH9; UbcM2; UBE2E3; Ubiquitin carrier protein E3; ubiquitin conjugating enzyme E2 E3; ubiquitin conjugating enzyme E2E 3; ubiquitin-conjugating enzyme 4; ubiquitin-conjugating enzyme E2 E3; Ubiquitin-conjugating enzyme E2-23 kDa; ubiquitin-conjugating enzyme E2E 3; ubiquitin-conjugating enzyme E2E 3 (homologous to yeast UBC4/5); ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2E 3, UBC4/5 homolog; ubiquitin-protein ligase E3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10477

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid