PIMA526010
COMMD1 Monoclonal Antibody (OTI2E2), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA526010-Each-of-1 | In Stock | ₹ 50,180.94 |
PIMA526010 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,180.94
GST (18%): ₹ 9,032.569
Total Price: ₹ 59,213.509
Antigen
COMMD1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q8N668
Gene Symbols
COMMD1
Immunogen
Full length human recombinant protein of COMMD1 produced in HEK293T cell
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone
OTI2E2
Conjugate
Unconjugated
Gene
COMMD1
Gene Alias
AI256843; C2orf5; COMM domain containing 1; COMM domain-containing protein 1; Commd1; copper metabolism (Murr1) domain containing 1; copper metabolism domain containing 1; copper metabolism gene MURR1; Murr1; Protein Murr1; U2/Mu; U2af1-rs1 region 1
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
150684
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Description
- Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins
- Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activiy and dissocoiates CAND1 from CUL1 and CUL2
- Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation
- Down-regulates NF-kappa-B activity
- Involved in the regulation of membrane expression and ubiquitination of SLC12A2
- Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits and by promoting their ubiquitination presumably involving NEDD4L
- Promotes the localization of SCNN1D to recycling endosomes
- Promotes CFTR cell surface expression through regulation of its ubiquitination
- Down-regulates SOD1 activity by interfering with its homodimerization
- Plays a role in copper ion homeostasis
- Involved in copper-dependent ATP7A trafficking between the trans- Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes
- Can bind one copper ion per monomer
- May function to facilitate biliary copper excretion within hepatocytes
- Binds to phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2)
- Involved in the regulation of HIF1A-mediated transcription; competes with ARNT/Hif-1-beta for binding to HIF1A resulting in decreased DNA binding and impaired transcriptional activation by HIF-1.
Compare Similar Items
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Antigen: COMMD1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q8N668
Gene Symbols: COMMD1
Immunogen: Full length human recombinant protein of COMMD1 produced in HEK293T cell
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone: OTI2E2
Conjugate: Unconjugated
Gene: COMMD1
Gene Alias: AI256843; C2orf5; COMM domain containing 1; COMM domain-containing protein 1; Commd1; copper metabolism (Murr1) domain containing 1; copper metabolism domain containing 1; copper metabolism gene MURR1; Murr1; Protein Murr1; U2/Mu; U2af1-rs1 region 1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 150684
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
COMMD1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q8N668
Gene Symbols:
COMMD1
Immunogen:
Full length human recombinant protein of COMMD1 produced in HEK293T cell
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2E2
Conjugate:
Unconjugated
Gene:
COMMD1
Gene Alias:
AI256843; C2orf5; COMM domain containing 1; COMM domain-containing protein 1; Commd1; copper metabolism (Murr1) domain containing 1; copper metabolism domain containing 1; copper metabolism gene MURR1; Murr1; Protein Murr1; U2/Mu; U2af1-rs1 region 1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
150684
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: COMMD1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q8K4M5, Q8N668, Q8WMD0
Gene Symbols: COMMD1
Immunogen: Full length human recombinant protein of COMMD1 produced in HEK293T cell
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone: OTI1F2
Conjugate: Unconjugated
Gene: COMMD1
Gene Alias: AI256843; C2orf5; COMM domain containing 1; COMM domain-containing protein 1; Commd1; copper metabolism (Murr1) domain containing 1; copper metabolism domain containing 1; copper metabolism gene MURR1; Murr1; Protein Murr1; U2/Mu; U2af1-rs1 region 1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 150684, 17846, 289831, 403590
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
COMMD1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q8K4M5, Q8N668, Q8WMD0
Gene Symbols:
COMMD1
Immunogen:
Full length human recombinant protein of COMMD1 produced in HEK293T cell
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI1F2
Conjugate:
Unconjugated
Gene:
COMMD1
Gene Alias:
AI256843; C2orf5; COMM domain containing 1; COMM domain-containing protein 1; Commd1; copper metabolism (Murr1) domain containing 1; copper metabolism domain containing 1; copper metabolism gene MURR1; Murr1; Protein Murr1; U2/Mu; U2af1-rs1 region 1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
150684, 17846, 289831, 403590
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: VBP1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P61758, P61759
Gene Symbols: Vbp1
Immunogen: Full length human recombinant protein of VBP1 produced in HEK293T cell
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI2G2
Conjugate: Unconjugated
Gene: Vbp1
Gene Alias: EGK_21124; HIBBJ46; LOC703257; PFD3; Pfdn3; phosphatidylinositol-binding clathrin assembly protein; prefoldin 3; prefoldin subunit 3; prefoldin subunit 3; phosphatidylinositol-binding clathrin assembly protein; RP13-228J13.4; VBP1; VBP-1; VHL binding protein 1; VHL binding protein-1; VHL-binding protein 1; von Hippel-Lindau binding protein 1; von Hippel-Lindau-binding protein 1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22327, 481089, 681825, 7411
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
VBP1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P61758, P61759
Gene Symbols:
Vbp1
Immunogen:
Full length human recombinant protein of VBP1 produced in HEK293T cell
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2G2
Conjugate:
Unconjugated
Gene:
Vbp1
Gene Alias:
EGK_21124; HIBBJ46; LOC703257; PFD3; Pfdn3; phosphatidylinositol-binding clathrin assembly protein; prefoldin 3; prefoldin subunit 3; prefoldin subunit 3; phosphatidylinositol-binding clathrin assembly protein; RP13-228J13.4; VBP1; VBP-1; VHL binding protein 1; VHL binding protein-1; VHL-binding protein 1; von Hippel-Lindau binding protein 1; von Hippel-Lindau-binding protein 1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22327, 481089, 681825, 7411
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: LRRC25
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q8N386
Gene Symbols: LRRC25
Immunogen: Full length human recombinant protein of LRRC25 produced in HEK293T cell
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Western Blot
Clone: OTI3E4
Conjugate: Unconjugated
Gene: LRRC25
Gene Alias: leucine rich repeat containing 25; leucine-rich repeat-containing protein 25; LRRC25; MAPA; monocyte and plasmacytoid activated molecule; monocyte and plasmacytoid-activated protein; UNQ6169/PRO20174
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 126364
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
LRRC25
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q8N386
Gene Symbols:
LRRC25
Immunogen:
Full length human recombinant protein of LRRC25 produced in HEK293T cell
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Western Blot
Clone:
OTI3E4
Conjugate:
Unconjugated
Gene:
LRRC25
Gene Alias:
leucine rich repeat containing 25; leucine-rich repeat-containing protein 25; LRRC25; MAPA; monocyte and plasmacytoid activated molecule; monocyte and plasmacytoid-activated protein; UNQ6169/PRO20174
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
126364
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid