PIMA526138

Alpha A Crystallin Monoclonal Antibody (OTI2C3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA526138-Each-of-1 In Stock ₹ 50,180.94

PIMA526138 - Each of 1

₹ 50,180.94

In Stock

Quantity

1

Base Price: ₹ 50,180.94

GST (18%): ₹ 9,032.569

Total Price: ₹ 59,213.509

Antigen

Alpha A Crystallin

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P02489

Gene Symbols

CRYAA, CRYAA2

Immunogen

Full length human recombinant protein of CRYAA produced in HEK293T cell

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI2C3

Conjugate

Unconjugated

Gene

CRYAA

Gene Alias

[a]A-crystallin; Acry 1; Acry-1; alpha A crystallin; alpha crystallin A chain; alpha-A-crystallin; alpha-crystallin A chain; Alpha-crystallin A(1-151); Alpha-crystallin A(1-156); Alpha-crystallin A(1-157); Alpha-crystallin A(1-162); Alpha-crystallin A(1-163); Alpha-crystallin A(1-165); Alpha-crystallin A(1-168); Alpha-crystallin A(1-172); Alpha-crystallin A2 chain; Alpha-crystallin A2(1-162); Alpha-crystallin A2(1-168); Alpha-crystallin A2(1-172); CRYA 1; Crya1; Crya-1; CRYAA; CRYAA2; Crystallin Alpha 1; crystallin alpha A; crystallin, alpha 1; crystallin, alpha A; Crystallin, alpha polypeptide A; crystallin, alpha-1; CTRCT9; DAcry-1; Heat shock protein beta-4; HSPB 4; HSPB4; human alphaA-crystallin (CRYA1); lens opacity 18; LOC102724652; lop18; small heat shock protein; wu:fc06h04; zgc:92036

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

102724652, 1409

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Lens proteins consist almost entirely of crystallins (about 95%)
  • Crystallins are also found vertebrate skeletal muscle tissue
  • In the lens, their structural function is to assist in maintaining the proper refractive index of the lens
  • The mammalian lens contains 3 major classes of crystallins: alpha, beta, and gamma
  • Alpha-crystallin is the largest of the crystallins and is composed of 2 primary gene products-alpha-A and alpha-B
  • There are at least 5 different proteins comprising the beta-crystallins
  • The gamma-crystallins are monomeric, but there are at least 5 gamma crystallins identified in bovine and rat lens
  • Alpha-Crystallin comprises 40% of total lens protein composition
  • In addition to maintaining proper refractive index, it also functions in a chaperone like manner by preventing the formation of aggregates possibly leading to cataract formation
  • It is believed that the phosphorylated states of the alpha-crystallin occur in response to cellular stress and may serve a structural control function and play a role in protein maintenance
  • Alpha-B crystallin has been linked to Alexander's disease where it accumulates in brain cells of those afflicted.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA526138

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Antigen:
Alpha A Crystallin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P02489

Gene Symbols:
CRYAA, CRYAA2

Immunogen:
Full length human recombinant protein of CRYAA produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2C3

Conjugate:
Unconjugated

Gene:
CRYAA

Gene Alias:
[a]A-crystallin; Acry 1; Acry-1; alpha A crystallin; alpha crystallin A chain; alpha-A-crystallin; alpha-crystallin A chain; Alpha-crystallin A(1-151); Alpha-crystallin A(1-156); Alpha-crystallin A(1-157); Alpha-crystallin A(1-162); Alpha-crystallin A(1-163); Alpha-crystallin A(1-165); Alpha-crystallin A(1-168); Alpha-crystallin A(1-172); Alpha-crystallin A2 chain; Alpha-crystallin A2(1-162); Alpha-crystallin A2(1-168); Alpha-crystallin A2(1-172); CRYA 1; Crya1; Crya-1; CRYAA; CRYAA2; Crystallin Alpha 1; crystallin alpha A; crystallin, alpha 1; crystallin, alpha A; Crystallin, alpha polypeptide A; crystallin, alpha-1; CTRCT9; DAcry-1; Heat shock protein beta-4; HSPB 4; HSPB4; human alphaA-crystallin (CRYA1); lens opacity 18; LOC102724652; lop18; small heat shock protein; wu:fc06h04; zgc:92036

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
102724652, 1409

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA526140

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Antigen:
FNDC4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9H6D8

Gene Symbols:
FNDC4

Immunogen:
Full length human recombinant protein of FNDC4 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin)

Clone:
OTI1B7

Conjugate:
Unconjugated

Gene:
FNDC4

Gene Alias:
2810430J06Rik; 6330410H20Rik; AB030187; AI838506; AW487863; fibronectin type III domain containing 4; fibronectin type III domain-containing protein 4; fibronectin type III repeat containing protein 1; fibronectin type III repeat-containing protein 1; Fndc4; Fnmp1; FRCP1; UNQ6389/PRO21134

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64838

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA526141

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Antigen:
NR1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
A2AI05, Q9UHB4

Gene Symbols:
NDOR1

Immunogen:
Full length human recombinant protein of NDOR1 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1E3

Conjugate:
Unconjugated

Gene:
NDOR1

Gene Alias:
4930447P04Rik; bA350O14.9; NADPH dependent diflavin oxidoreductase 1; NADPH-dependent diflavin oxidoreductase 1; NADPH-dependent FMN and FAD-containing oxidoreductase; Ndor; NDOR1; Novel reductase 1; NR1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27158, 491234, 78797

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA526142

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Antigen:
RhoJ

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9H4E5

Gene Symbols:
RHOJ

Immunogen:
Full length human recombinant protein of RHOJ produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2C10

Conjugate:
Unconjugated

Gene:
RHOJ

Gene Alias:
1110005O19Rik; Arhj; AW210585; FLJ14445; MGC34777; ras homolog family member J; ras homolog gene family, member J; RASL7B; ras-like protein family member 7B; RAS-like, family 7, member B; RHOI; RHOJ; Rho-related GTP-binding protein RhoJ; Rhot; si:dkey-100h21.1; TC10B; Tc10l; tc10-like GTP-binding protein; tc10-like GTP-binding protein TCL; TC10-like Rho GTPase; TCL

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57381

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid