PIMA526164

Alpha A Crystallin Monoclonal Antibody (OTI3B12), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA526164-Each-of-1 In Stock ₹ 50,180.94

PIMA526164 - Each of 1

₹ 50,180.94

In Stock

Quantity

1

Base Price: ₹ 50,180.94

GST (18%): ₹ 9,032.569

Total Price: ₹ 59,213.509

Antigen

Alpha A Crystallin

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P02489

Gene Symbols

CRYAA, CRYAA2

Immunogen

Full length human recombinant protein of CRYAA produced in HEK293T cell

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI3B12

Conjugate

Unconjugated

Gene

CRYAA

Gene Alias

[a]A-crystallin; Acry 1; Acry-1; alpha A crystallin; alpha crystallin A chain; alpha-A-crystallin; alpha-crystallin A chain; Alpha-crystallin A(1-151); Alpha-crystallin A(1-156); Alpha-crystallin A(1-157); Alpha-crystallin A(1-162); Alpha-crystallin A(1-163); Alpha-crystallin A(1-165); Alpha-crystallin A(1-168); Alpha-crystallin A(1-172); Alpha-crystallin A2 chain; Alpha-crystallin A2(1-162); Alpha-crystallin A2(1-168); Alpha-crystallin A2(1-172); CRYA 1; Crya1; Crya-1; CRYAA; CRYAA2; Crystallin Alpha 1; crystallin alpha A; crystallin, alpha 1; crystallin, alpha A; Crystallin, alpha polypeptide A; crystallin, alpha-1; CTRCT9; DAcry-1; Heat shock protein beta-4; HSPB 4; HSPB4; human alphaA-crystallin (CRYA1); lens opacity 18; LOC102724652; lop18; small heat shock protein; wu:fc06h04; zgc:92036

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

102724652, 1409

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Description

  • Lens proteins consist almost entirely of crystallins (about 95%)
  • Crystallins are also found vertebrate skeletal muscle tissue
  • In the lens, their structural function is to assist in maintaining the proper refractive index of the lens
  • The mammalian lens contains 3 major classes of crystallins: alpha, beta, and gamma
  • Alpha-crystallin is the largest of the crystallins and is composed of 2 primary gene products-alpha-A and alpha-B
  • There are at least 5 different proteins comprising the beta-crystallins
  • The gamma-crystallins are monomeric, but there are at least 5 gamma crystallins identified in bovine and rat lens
  • Alpha-Crystallin comprises 40% of total lens protein composition
  • In addition to maintaining proper refractive index, it also functions in a chaperone like manner by preventing the formation of aggregates possibly leading to cataract formation
  • It is believed that the phosphorylated states of the alpha-crystallin occur in response to cellular stress and may serve a structural control function and play a role in protein maintenance
  • Alpha-B crystallin has been linked to Alexander's disease where it accumulates in brain cells of those afflicted.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA526164

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Antigen:
Alpha A Crystallin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P02489

Gene Symbols:
CRYAA, CRYAA2

Immunogen:
Full length human recombinant protein of CRYAA produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3B12

Conjugate:
Unconjugated

Gene:
CRYAA

Gene Alias:
[a]A-crystallin; Acry 1; Acry-1; alpha A crystallin; alpha crystallin A chain; alpha-A-crystallin; alpha-crystallin A chain; Alpha-crystallin A(1-151); Alpha-crystallin A(1-156); Alpha-crystallin A(1-157); Alpha-crystallin A(1-162); Alpha-crystallin A(1-163); Alpha-crystallin A(1-165); Alpha-crystallin A(1-168); Alpha-crystallin A(1-172); Alpha-crystallin A2 chain; Alpha-crystallin A2(1-162); Alpha-crystallin A2(1-168); Alpha-crystallin A2(1-172); CRYA 1; Crya1; Crya-1; CRYAA; CRYAA2; Crystallin Alpha 1; crystallin alpha A; crystallin, alpha 1; crystallin, alpha A; Crystallin, alpha polypeptide A; crystallin, alpha-1; CTRCT9; DAcry-1; Heat shock protein beta-4; HSPB 4; HSPB4; human alphaA-crystallin (CRYA1); lens opacity 18; LOC102724652; lop18; small heat shock protein; wu:fc06h04; zgc:92036

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
102724652, 1409

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA526165

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Antigen:
PGD

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P52209

Gene Symbols:
PGD

Immunogen:
Full length human recombinant protein of PGD produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2A5

Conjugate:
Unconjugated

Gene:
PGD

Gene Alias:
0610042A05Rik; 6PGD; 6-phosphogluconate dehydrogenase, decarboxylating; 6-phosphogluconate dehydrogenase, decarboxylating-like; AU019875; C78335; LOC100360180; Pgd; PGDH; phosphogluconate dehydrogenase

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5226

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA526166

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Antigen:
NR1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9UHB4

Gene Symbols:
NDOR1

Immunogen:
Full length human recombinant protein of NDOR1 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2G4

Conjugate:
Unconjugated

Gene:
NDOR1

Gene Alias:
4930447P04Rik; bA350O14.9; NADPH dependent diflavin oxidoreductase 1; NADPH-dependent diflavin oxidoreductase 1; NADPH-dependent FMN and FAD-containing oxidoreductase; Ndor; NDOR1; Novel reductase 1; NR1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27158

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA526168

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Antigen:
GBAS

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O75323

Gene Symbols:
NIPSNAP2

Immunogen:
Full length human recombinant protein of GBAS produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
OTI1B2

Conjugate:
Unconjugated

Gene:
NIPSNAP2

Gene Alias:
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like 2; AV006093; GBAS; glioblastoma amplified sequence; glioblastoma-amplified sequence; nipsnap homolog 2; NIPSNAP2; Protein NipSnap homolog 2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2631

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid