PIMA526198
MDMX Monoclonal Antibody (OTI4G5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA526198-Each-of-1 | In Stock | ₹ 50,180.94 |
PIMA526198 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,180.94
GST (18%): ₹ 9,032.569
Total Price: ₹ 59,213.509
Antigen
MDMX
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
O15151
Gene Symbols
MDM4
Immunogen
Full length human recombinant protein of MDM4 produced in HEK293T cell
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
OTI4G5
Conjugate
Unconjugated
Gene
MDM4
Gene Alias
4933417N07Rik; AA414968; AL023055; AU018793; AU021806; C85810; DKFZp781B1423; double minute 4 homolog; double minute 4 protein; double minute 4, human homolog of; p53-binding protein; HDMX; human homolog of; Mdm2-like p53-binding protein; MDM4; Mdm4 p53 binding protein homolog; MDM4 protein variant G; MDM4 protein variant Y; MDM4, p53 regulator; MDM4-related protein 1; Mdmx; MGC132766; MRP1; p53-binding protein Mdm4; Protein Mdm4; protein Mdmx; RP11-430C7.1; transformed mouse 3T3 cell double minute 4
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4194
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Description
- The MDM2 protein is the primary regulator of p53 protein stability
- MDMX is an MDM2-related protein that inhibits MDM2-mediated degradation of p53 via distinct associations with MDM2
- The gene that encodes MDMX (also designated MDM4) is a target for amplification in malignant gliomas
- ARF interacts with MDMX to sequester MDMX within the nucleolus
- This sequestration of MDMX by ARF results in an increase in p53 transactivation
- In addition, expression of MDMX can reverse MDM2-targeted degradation of p53 while maintaining suppression of p53 transactivation
- Like MDM2, MDMX also binds p73 and stabilizes the level of p73
- Therefore, in striking contrast to p53, the half-life of p73 is increased by binding to MDM2.
Compare Similar Items
Show Difference
Antigen: MDMX
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: O15151
Gene Symbols: MDM4
Immunogen: Full length human recombinant protein of MDM4 produced in HEK293T cell
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: OTI4G5
Conjugate: Unconjugated
Gene: MDM4
Gene Alias: 4933417N07Rik; AA414968; AL023055; AU018793; AU021806; C85810; DKFZp781B1423; double minute 4 homolog; double minute 4 protein; double minute 4, human homolog of; p53-binding protein; HDMX; human homolog of; Mdm2-like p53-binding protein; MDM4; Mdm4 p53 binding protein homolog; MDM4 protein variant G; MDM4 protein variant Y; MDM4, p53 regulator; MDM4-related protein 1; Mdmx; MGC132766; MRP1; p53-binding protein Mdm4; Protein Mdm4; protein Mdmx; RP11-430C7.1; transformed mouse 3T3 cell double minute 4
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4194
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
MDMX
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O15151
Gene Symbols:
MDM4
Immunogen:
Full length human recombinant protein of MDM4 produced in HEK293T cell
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI4G5
Conjugate:
Unconjugated
Gene:
MDM4
Gene Alias:
4933417N07Rik; AA414968; AL023055; AU018793; AU021806; C85810; DKFZp781B1423; double minute 4 homolog; double minute 4 protein; double minute 4, human homolog of; p53-binding protein; HDMX; human homolog of; Mdm2-like p53-binding protein; MDM4; Mdm4 p53 binding protein homolog; MDM4 protein variant G; MDM4 protein variant Y; MDM4, p53 regulator; MDM4-related protein 1; Mdmx; MGC132766; MRP1; p53-binding protein Mdm4; Protein Mdm4; protein Mdmx; RP11-430C7.1; transformed mouse 3T3 cell double minute 4
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4194
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: BBOX1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: O75936
Gene Symbols: BBOX1
Immunogen: Full length human recombinant protein of BBOX1 produced in HEK293T cell
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: OTI1E11
Conjugate: Unconjugated
Gene: BBOX1
Gene Alias: AI874739; BBH; BBOX; Bbox1; butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1; butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase); gamma-BBH; Gamma-butyrobetaine dioxygenase; gamma-butyrobetaine hydroxylase; gamma-butyrobetaine hydroxylase 1; gamma-butyrobetaine,2-oxoglutarate dioxygenase; gamma-butyrobetaine,2-oxoglutarate dioxygenase 1; G-BBH
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8424
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
BBOX1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O75936
Gene Symbols:
BBOX1
Immunogen:
Full length human recombinant protein of BBOX1 produced in HEK293T cell
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI1E11
Conjugate:
Unconjugated
Gene:
BBOX1
Gene Alias:
AI874739; BBH; BBOX; Bbox1; butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1; butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase); gamma-BBH; Gamma-butyrobetaine dioxygenase; gamma-butyrobetaine hydroxylase; gamma-butyrobetaine hydroxylase 1; gamma-butyrobetaine,2-oxoglutarate dioxygenase; gamma-butyrobetaine,2-oxoglutarate dioxygenase 1; G-BBH
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8424
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: RAB21
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P35282, P55745, Q6AXT5, Q9UL25
Gene Symbols: RAB21
Immunogen: Full length human recombinant protein of RAB21 produced in HEK293T cell
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG2b
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: OTI6E12
Conjugate: Unconjugated
Gene: RAB21
Gene Alias: 9630024B22; GTP-binding protein RAB21; KIAA0118; Rab-12; Rab21; RAB21, member RAS oncogene family; ras-related protein Rab-21
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100683312, 216344, 23011, 299799
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
RAB21
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P35282, P55745, Q6AXT5, Q9UL25
Gene Symbols:
RAB21
Immunogen:
Full length human recombinant protein of RAB21 produced in HEK293T cell
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI6E12
Conjugate:
Unconjugated
Gene:
RAB21
Gene Alias:
9630024B22; GTP-binding protein RAB21; KIAA0118; Rab-12; Rab21; RAB21, member RAS oncogene family; ras-related protein Rab-21
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100683312, 216344, 23011, 299799
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: RAB21
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P35282, P55745, Q6AXT5, Q9UL25
Gene Symbols: RAB21
Immunogen: Full length human recombinant protein of RAB21 produced in HEK293T cell
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG2b
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: OTI6F11
Conjugate: Unconjugated
Gene: RAB21
Gene Alias: 9630024B22; GTP-binding protein RAB21; KIAA0118; Rab-12; Rab21; RAB21, member RAS oncogene family; ras-related protein Rab-21
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100683312, 216344, 23011, 299799
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
RAB21
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P35282, P55745, Q6AXT5, Q9UL25
Gene Symbols:
RAB21
Immunogen:
Full length human recombinant protein of RAB21 produced in HEK293T cell
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI6F11
Conjugate:
Unconjugated
Gene:
RAB21
Gene Alias:
9630024B22; GTP-binding protein RAB21; KIAA0118; Rab-12; Rab21; RAB21, member RAS oncogene family; ras-related protein Rab-21
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100683312, 216344, 23011, 299799
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid