PIMA526427
RIP1 Monoclonal Antibody (OTI2G3), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA526427-Each-of-1 | In Stock | ₹ 50,266.50 |
PIMA526427 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,266.50
GST (18%): ₹ 9,047.97
Total Price: ₹ 59,314.47
Antigen
RIP1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q13546
Gene Symbols
RIPK1
Immunogen
Human recombinant protein fragment corresponding to amino acids 133-422 of RIPK1 produced in E.coli
Quantity
100μL
Primary or Secondary
Primary
Target Species
Canine, Human
Product Type
Antibody
Isotype
IgG2a
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI2G3
Conjugate
Unconjugated
Gene
RIPK1
Gene Alias
cell death protein RIP; D330015H01Rik; FLJ39204; OTTHUMP00000015955; receptor (TNFRSF)-interacting serine-threonine kinase 1; receptor interacting serine/threonine kinase 1; receptor-interacting protein 1; receptor-interacting protein kinase 1; receptor-interacting serine/threonine-protein kinase 1; Rinp; RIP; RIP1; RIP-1; RIP1 (CT); RIPK1; serine/threonine-protein kinase RIP
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
102152063, 8737
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Description
- Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage
- Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor
- Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade
- Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules
- Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation
- Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death
- RIPK1 and RIPK3 association, in particular, forms a necrosis-inducing complex.
Compare Similar Items
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Antigen: RIP1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q13546
Gene Symbols: RIPK1
Immunogen: Human recombinant protein fragment corresponding to amino acids 133-422 of RIPK1 produced in E.coli
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Canine, Human
Product Type: Antibody
Isotype: IgG2a
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI2G3
Conjugate: Unconjugated
Gene: RIPK1
Gene Alias: cell death protein RIP; D330015H01Rik; FLJ39204; OTTHUMP00000015955; receptor (TNFRSF)-interacting serine-threonine kinase 1; receptor interacting serine/threonine kinase 1; receptor-interacting protein 1; receptor-interacting protein kinase 1; receptor-interacting serine/threonine-protein kinase 1; Rinp; RIP; RIP1; RIP-1; RIP1 (CT); RIPK1; serine/threonine-protein kinase RIP
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 102152063, 8737
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
RIP1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q13546
Gene Symbols:
RIPK1
Immunogen:
Human recombinant protein fragment corresponding to amino acids 133-422 of RIPK1 produced in E.coli
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Canine, Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2G3
Conjugate:
Unconjugated
Gene:
RIPK1
Gene Alias:
cell death protein RIP; D330015H01Rik; FLJ39204; OTTHUMP00000015955; receptor (TNFRSF)-interacting serine-threonine kinase 1; receptor interacting serine/threonine kinase 1; receptor-interacting protein 1; receptor-interacting protein kinase 1; receptor-interacting serine/threonine-protein kinase 1; Rinp; RIP; RIP1; RIP-1; RIP1 (CT); RIPK1; serine/threonine-protein kinase RIP
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
102152063, 8737
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: PHKG2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P15735
Gene Symbols: PHKG2
Immunogen: Human recombinant protein fragment corresponding to amino acids 1-216 of PHKG2 produced in E.coli
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI1F9
Conjugate: Unconjugated
Gene: PHKG2
Gene Alias: 1500017I02Rik; GSD9C; MGC129049 protein; phkg2; PHK-gamma-LT; PHK-gamma-T; Phosphorylase b kinase gamma catalytic chain, liver/testis isoform; phosphorylase b kinase gamma catalytic chain, testis/liver isoform; phosphorylase kinase; phosphorylase kinase catalytic subunit gamma 2; phosphorylase kinase gamma subunit 2; phosphorylase kinase subunit gamma 2; phosphorylase kinase subunit gamma-2; phosphorylase kinase, gamma 2 (testis); Phosphorylase kinase, gamma 2 (testis/liver); PSK-C3; serine/threonine-protein kinase PHKG2; similar to phosphorylase kinase, gamma 2 (testis); zgc:55863; zgc:55863 protein
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5261
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
PHKG2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P15735
Gene Symbols:
PHKG2
Immunogen:
Human recombinant protein fragment corresponding to amino acids 1-216 of PHKG2 produced in E.coli
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI1F9
Conjugate:
Unconjugated
Gene:
PHKG2
Gene Alias:
1500017I02Rik; GSD9C; MGC129049 protein; phkg2; PHK-gamma-LT; PHK-gamma-T; Phosphorylase b kinase gamma catalytic chain, liver/testis isoform; phosphorylase b kinase gamma catalytic chain, testis/liver isoform; phosphorylase kinase; phosphorylase kinase catalytic subunit gamma 2; phosphorylase kinase gamma subunit 2; phosphorylase kinase subunit gamma 2; phosphorylase kinase subunit gamma-2; phosphorylase kinase, gamma 2 (testis); Phosphorylase kinase, gamma 2 (testis/liver); PSK-C3; serine/threonine-protein kinase PHKG2; similar to phosphorylase kinase, gamma 2 (testis); zgc:55863; zgc:55863 protein
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5261
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: MORF4
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: 0
Gene Symbols: MORF4
Immunogen: Human recombinant protein fragment corresponding to amino acids 1-255 of MORF4 produced in E.coli
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI1B12
Conjugate: Unconjugated
Gene: MORF4
Gene Alias: 9130413I22Rik; AL022827; csrb; Eaf3; Esa1p-associated factor 3 homolog; FWP006; HSPC008; HSPC061; HsT17725; MEAF3; mKIAA4002; MNCb-1039; Mof4 family associated protein 1; Morf4 family associated protein 1; MORF4 family-associated protein 1; MORF4L1; MORF-related gene 15 protein; MORF-related gene on chromosome 15; MORFRG15; mortality factor 4 like 1; mortality factor 4-like protein 1; Mrfap1; mrfap1 {ECO:0000312; MRG15; Pam14; Pgr1; PP368; Protein associated with MRG of 14 kDa; protein associated with MRG, 14 kDa; protein MSL3-1; RGD:628631}; RGD1306635; S863-6; SEN1; T-cell activation protein; T-cell activation protein-related protein; TEG-189; testis expressed gene 189; testis-expressed gene 189 protein; Tex189; transcription factor-like protein MRG15
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10934
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
MORF4
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
0
Gene Symbols:
MORF4
Immunogen:
Human recombinant protein fragment corresponding to amino acids 1-255 of MORF4 produced in E.coli
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI1B12
Conjugate:
Unconjugated
Gene:
MORF4
Gene Alias:
9130413I22Rik; AL022827; csrb; Eaf3; Esa1p-associated factor 3 homolog; FWP006; HSPC008; HSPC061; HsT17725; MEAF3; mKIAA4002; MNCb-1039; Mof4 family associated protein 1; Morf4 family associated protein 1; MORF4 family-associated protein 1; MORF4L1; MORF-related gene 15 protein; MORF-related gene on chromosome 15; MORFRG15; mortality factor 4 like 1; mortality factor 4-like protein 1; Mrfap1; mrfap1 {ECO:0000312; MRG15; Pam14; Pgr1; PP368; Protein associated with MRG of 14 kDa; protein associated with MRG, 14 kDa; protein MSL3-1; RGD:628631}; RGD1306635; S863-6; SEN1; T-cell activation protein; T-cell activation protein-related protein; TEG-189; testis expressed gene 189; testis-expressed gene 189 protein; Tex189; transcription factor-like protein MRG15
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10934
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: ARL2BP
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q9D385, Q9Y2Y0
Gene Symbols: ARL2BP
Immunogen: Full length human recombinant protein of ARL2BP produced in E.coli
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse, Non-human Primate
Product Type: Antibody
Isotype: IgG2b
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI1F8
Conjugate: Unconjugated
Gene: ARL2BP
Gene Alias: 1700010P10Rik; 1700027H16Rik; 6330544B05Rik; ADP ribosylation factor like GTPase 2 binding protein; ADP-ribosylation factor like 2 binding protein; ADP-ribosylation factor like GTPase 2 binding protein; ADP-ribosylation factor-like 2 binding protein; ADP-ribosylation factor-like protein 2-binding protein; ADP-ribosylation-like 2 binding protein; AI482273; AI849834; Arf-like 2 binding protein BART1; ARF-like 2-binding protein; ARL2-binding protein; Arl2bp; Bart; BART1; binder of ARF2 protein 1; binder of Arl Two; binder of Arl2; QtsA-10827; retinitis pigmentosa 66 (autosomal recessive); RP66; unnamed protein product
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 107566, 23568, 611248
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ARL2BP
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q9D385, Q9Y2Y0
Gene Symbols:
ARL2BP
Immunogen:
Full length human recombinant protein of ARL2BP produced in E.coli
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse, Non-human Primate
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI1F8
Conjugate:
Unconjugated
Gene:
ARL2BP
Gene Alias:
1700010P10Rik; 1700027H16Rik; 6330544B05Rik; ADP ribosylation factor like GTPase 2 binding protein; ADP-ribosylation factor like 2 binding protein; ADP-ribosylation factor like GTPase 2 binding protein; ADP-ribosylation factor-like 2 binding protein; ADP-ribosylation factor-like protein 2-binding protein; ADP-ribosylation-like 2 binding protein; AI482273; AI849834; Arf-like 2 binding protein BART1; ARF-like 2-binding protein; ARL2-binding protein; Arl2bp; Bart; BART1; binder of ARF2 protein 1; binder of Arl Two; binder of Arl2; QtsA-10827; retinitis pigmentosa 66 (autosomal recessive); RP66; unnamed protein product
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
107566, 23568, 611248
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid