PIMA526661
UFD1L Monoclonal Antibody (OTI7C9), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA526661-Each-of-1 | In Stock | ₹ 52,198.50 |
PIMA526661 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,198.50
GST (18%): ₹ 9,395.73
Total Price: ₹ 61,594.23
Antigen
UFD1L
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q92890
Gene Symbols
UFD1
Immunogen
Full length human recombinant protein of UFD1L produced in E.coli
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI7C9
Conjugate
Unconjugated
Gene
UFD1
Gene Alias
RGD:619822}; UB fusion protein 1; UB fusion protein 1 {ECO:0000250; ubiquitin fusion degradation 1 like; ubiquitin fusion degradation 1 like (yeast); Ubiquitin fusion degradation protein 1; Ubiquitin fusion degradation protein 1 homolog; ubiquitin fusion degradation protein 1 homolog {ECO:0000250; Ubiquitin recognition factor in ER-associated degradation protein 1; UFD1; UFD1L; ufd1l {ECO:0000312; UniProtKB:Q92890}
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
7353
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Description
- Ubiquitin-mediated proteolysis requires the transfer of ubiquitin (Ub) to lysine groups on selected cellular proteins, which then potentiates the proteolytic degradation of these protein conjugates by the 26S proteasome
- Ub-fusions are cleaved by Ub-specific processing proteases (UBps) or alternatively by the Ub-fusion degradation (UFD) pathway
- The UBP pathway targets the C-terminal glycine residue on Ub that is involved in the formation of Ub-conjugates, while UFD proteins preferentially cleave Ub-conjugated proteins that contain an amino acid substitution at this glycine residue
- The UFD1 protein was originally characterized in the yeast S
- cerevisiae and subsequently, the human homolog UFD1 or UFD1L was identified
- In vitro, UFD1 attenuates the degradation of Ub-fusions, which have a proline or valine residue substituted at the Gly76 moiety, by the selective multiubiquitination of the Ub chain of the Ub-conjugate
- Mutations within the UFD1 gene are implicated in the development of CATCH22 syndrome, which is characterized by cardiac defects, cleft palate and hypocalcemia, suggesting that this proteolytic pathway may be involved in the progression of these developmental defects.
Compare Similar Items
Show Difference
Antigen: UFD1L
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q92890
Gene Symbols: UFD1
Immunogen: Full length human recombinant protein of UFD1L produced in E.coli
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI7C9
Conjugate: Unconjugated
Gene: UFD1
Gene Alias: RGD:619822}; UB fusion protein 1; UB fusion protein 1 {ECO:0000250; ubiquitin fusion degradation 1 like; ubiquitin fusion degradation 1 like (yeast); Ubiquitin fusion degradation protein 1; Ubiquitin fusion degradation protein 1 homolog; ubiquitin fusion degradation protein 1 homolog {ECO:0000250; Ubiquitin recognition factor in ER-associated degradation protein 1; UFD1; UFD1L; ufd1l {ECO:0000312; UniProtKB:Q92890}
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7353
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
UFD1L
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q92890
Gene Symbols:
UFD1
Immunogen:
Full length human recombinant protein of UFD1L produced in E.coli
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI7C9
Conjugate:
Unconjugated
Gene:
UFD1
Gene Alias:
RGD:619822}; UB fusion protein 1; UB fusion protein 1 {ECO:0000250; ubiquitin fusion degradation 1 like; ubiquitin fusion degradation 1 like (yeast); Ubiquitin fusion degradation protein 1; Ubiquitin fusion degradation protein 1 homolog; ubiquitin fusion degradation protein 1 homolog {ECO:0000250; Ubiquitin recognition factor in ER-associated degradation protein 1; UFD1; UFD1L; ufd1l {ECO:0000312; UniProtKB:Q92890}
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7353
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: DDX6
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P26196
Gene Symbols: DDX6
Immunogen: Human recombinant protein fragment corresponding to amino acids 1-298 of DDX6 produced in E.coli
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI2D6
Conjugate: Unconjugated
Gene: DDX6
Gene Alias: 1110001P04Rik; ATP-dependent RNA helicase p54; DDX6; D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 6; DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 6; DEAD (Asp-Glu-Ala-Asp) box helicase 6; DEAD (Asp-Glu-Ala-Asp) box polypeptide 6; DEAD box protein 6; DEAD box-6; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 (RNA helicase, 54kD); DEAD-box helicase 6; DEAD-box protein 6; E230023J21Rik; HLR2; mRCK/P54; Oncogene RCK; oncogene RCK homolog; p54; probable ATP-dependent RNA helicase DDX6; RCK; RGD1564560
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1656
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
DDX6
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P26196
Gene Symbols:
DDX6
Immunogen:
Human recombinant protein fragment corresponding to amino acids 1-298 of DDX6 produced in E.coli
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2D6
Conjugate:
Unconjugated
Gene:
DDX6
Gene Alias:
1110001P04Rik; ATP-dependent RNA helicase p54; DDX6; D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 6; DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 6; DEAD (Asp-Glu-Ala-Asp) box helicase 6; DEAD (Asp-Glu-Ala-Asp) box polypeptide 6; DEAD box protein 6; DEAD box-6; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 (RNA helicase, 54kD); DEAD-box helicase 6; DEAD-box protein 6; E230023J21Rik; HLR2; mRCK/P54; Oncogene RCK; oncogene RCK homolog; p54; probable ATP-dependent RNA helicase DDX6; RCK; RGD1564560
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1656
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: BFSP2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q13515
Gene Symbols: BFSP2
Immunogen: Human recombinant protein fragment corresponding to amino acids 184-415 of BFSP2 produced in E.coli
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI1C2
Conjugate: Unconjugated
Gene: BFSP2
Gene Alias: 49 kDa cytoskeletal protein; AI448593; beaded filament protein CP49; beaded filament structural protein 2; beaded filament structural protein 2, phakinin; bfps2, Cytoskeletal protein, 49-kD; BFSP2; CP 47; CP47; CP49; CTRCT12; DKEYP-73D8.2; hypothetical protein LOC494090; lens fiber cell beaded filament protein CP 47; Lens fiber cell beaded filament protein CP 49; lens intermediate filament-like light; LIFL-L; MGC142078; MGC142080; phakinin; PHAKOSIN; zgc:103750
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8419
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
BFSP2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q13515
Gene Symbols:
BFSP2
Immunogen:
Human recombinant protein fragment corresponding to amino acids 184-415 of BFSP2 produced in E.coli
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI1C2
Conjugate:
Unconjugated
Gene:
BFSP2
Gene Alias:
49 kDa cytoskeletal protein; AI448593; beaded filament protein CP49; beaded filament structural protein 2; beaded filament structural protein 2, phakinin; bfps2, Cytoskeletal protein, 49-kD; BFSP2; CP 47; CP47; CP49; CTRCT12; DKEYP-73D8.2; hypothetical protein LOC494090; lens fiber cell beaded filament protein CP 47; Lens fiber cell beaded filament protein CP 49; lens intermediate filament-like light; LIFL-L; MGC142078; MGC142080; phakinin; PHAKOSIN; zgc:103750
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8419
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: BFSP2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q13515
Gene Symbols: BFSP2
Immunogen: Human recombinant protein fragment corresponding to amino acids 184-415 of BFSP2 produced in E.coli
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI4E7
Conjugate: Unconjugated
Gene: BFSP2
Gene Alias: 49 kDa cytoskeletal protein; AI448593; beaded filament protein CP49; beaded filament structural protein 2; beaded filament structural protein 2, phakinin; bfps2, Cytoskeletal protein, 49-kD; BFSP2; CP 47; CP47; CP49; CTRCT12; DKEYP-73D8.2; hypothetical protein LOC494090; lens fiber cell beaded filament protein CP 47; Lens fiber cell beaded filament protein CP 49; lens intermediate filament-like light; LIFL-L; MGC142078; MGC142080; phakinin; PHAKOSIN; zgc:103750
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8419
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
BFSP2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q13515
Gene Symbols:
BFSP2
Immunogen:
Human recombinant protein fragment corresponding to amino acids 184-415 of BFSP2 produced in E.coli
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI4E7
Conjugate:
Unconjugated
Gene:
BFSP2
Gene Alias:
49 kDa cytoskeletal protein; AI448593; beaded filament protein CP49; beaded filament structural protein 2; beaded filament structural protein 2, phakinin; bfps2, Cytoskeletal protein, 49-kD; BFSP2; CP 47; CP47; CP49; CTRCT12; DKEYP-73D8.2; hypothetical protein LOC494090; lens fiber cell beaded filament protein CP 47; Lens fiber cell beaded filament protein CP 49; lens intermediate filament-like light; LIFL-L; MGC142078; MGC142080; phakinin; PHAKOSIN; zgc:103750
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8419
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid