PIMA526741

TLK2 Monoclonal Antibody (OTI2H2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA526741-Each-of-1 In Stock ₹ 50,180.94

PIMA526741 - Each of 1

₹ 50,180.94

In Stock

Quantity

1

Base Price: ₹ 50,180.94

GST (18%): ₹ 9,032.569

Total Price: ₹ 59,213.509

Antigen

TLK2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q86UE8

Gene Symbols

Tlk2

Immunogen

Human recombinant protein fragment corresponding to amino acids 1-296 of TLK2 produced in E.coli

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin)

Clone

OTI2H2

Conjugate

Unconjugated

Gene

Tlk2

Gene Alias

4933403M19Rik; HsHPK; PKUalpha; PKU-alpha; protein kinase U-alpha; serine/threonine-protein kinase tousled-like 2; Tlk; Tlk2; tousled like kinase 2; tousled-like kinase 2; tousled-like kinase 2 (Arabidopsis)

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11011

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Description

  • TLK2 or Tousled-like kinase 2, is a nuclear serine/threonine kinases that is thought to be involved in the regulation of chromatin assembly
  • In addition, TLK2 is also involved in other cellular processes such as intracellular signaling cascade, protein amino acid phosphorylation, cell cycle, chromatin modification and in response to DNA damage stimulus
  • TLK2 displays maximal activity during S phase of the cell cycle where it appears to be regulated by cell-cycle-dependent phosphorylation
  • Inhibition of DNA replication causes a rapid loss of TLK2 activity, indicating that TLK2 function is tightly linked to ongoing DNA replication
  • The TLK2 enzyme is cell-cycle regulated, with maximal activity in S-phase
  • It is inactivated by phosphorylation at Ser-750, potentially by CHK1
  • TLK2 heterodimerizes with TLK1
  • This nuclear protein is widely expressed, with presence in fetal placenta, liver, kidney, pancreas, heart and skeletal muscle tissues, and in several adult cell lines.

Compare Similar Items

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Img

Thermo Scientific

PIMA526741

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Antigen:
TLK2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q86UE8

Gene Symbols:
Tlk2

Immunogen:
Human recombinant protein fragment corresponding to amino acids 1-296 of TLK2 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin)

Clone:
OTI2H2

Conjugate:
Unconjugated

Gene:
Tlk2

Gene Alias:
4933403M19Rik; HsHPK; PKUalpha; PKU-alpha; protein kinase U-alpha; serine/threonine-protein kinase tousled-like 2; Tlk; Tlk2; tousled like kinase 2; tousled-like kinase 2; tousled-like kinase 2 (Arabidopsis)

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11011

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA526742

--


Antigen:
GFI1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q99684

Gene Symbols:
GFI1

Immunogen:
Human recombinant protein fragment corresponding to amino acids 1-180 of GFI1 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI6E8

Conjugate:
Unconjugated

Gene:
GFI1

Gene Alias:
AW495828; FLJ94509; Gfi1; GFI-1; GFI1A; growth factor independence-1; growth factor independent 1; growth factor independent 1 transcription repressor; growth factor independent 1 transcriptional repressor; growth factor independent protein 1; Growth factor independent-1; Pal1; Pal-1; SCN2; Zinc finger protein 163; zinc finger protein Gfi-1; ZNF163

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2672

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA526743

--


Antigen:
NUDT12

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9BQG2

Gene Symbols:
Nudt12

Immunogen:
Human recombinant protein fragment corresponding to amino acids 1-251 of NUDT12 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1A2

Conjugate:
Unconjugated

Gene:
Nudt12

Gene Alias:
0610016O18Rik; DKFZP761I172; MGC137455 protein; nucleoside diphosphate linked moiety X-type motif 12; nucleoside diphosphate-linked moiety X motif 12; nudix (nucleoside diphosphate linked moiety X)-type motif 12; nudix (nucleoside diphosphnudix (nucleoside diphosphate linked moiety X)-type motif 12ate linked moiety X)-type motif 12; nudix hydrolase 12; nudix motif 12; nudix-type motif 12; NUDT12; Peroxisomal NADH pyrophosphatase NUDT12

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
83594

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA526745

--


Antigen:
NUDT12

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9BQG2

Gene Symbols:
Nudt12

Immunogen:
Human recombinant protein fragment corresponding to amino acids 1-251 of NUDT12 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2G2

Conjugate:
Unconjugated

Gene:
Nudt12

Gene Alias:
0610016O18Rik; DKFZP761I172; MGC137455 protein; nucleoside diphosphate linked moiety X-type motif 12; nucleoside diphosphate-linked moiety X motif 12; nudix (nucleoside diphosphate linked moiety X)-type motif 12; nudix (nucleoside diphosphnudix (nucleoside diphosphate linked moiety X)-type motif 12ate linked moiety X)-type motif 12; nudix hydrolase 12; nudix motif 12; nudix-type motif 12; NUDT12; Peroxisomal NADH pyrophosphatase NUDT12

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
83594

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid