PIMA526848

INAVA Monoclonal Antibody (OTI6A6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA526848-Each-of-1 In Stock ₹ 50,180.94

PIMA526848 - Each of 1

₹ 50,180.94

In Stock

Quantity

1

Base Price: ₹ 50,180.94

GST (18%): ₹ 9,032.569

Total Price: ₹ 59,213.509

Antigen

INAVA

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q3KP66

Gene Symbols

C1orf106

Immunogen

Human recombinant protein fragment corresponding to amino acids 1-270 of C1ORF106 produced in E.coli

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI6A6

Conjugate

Unconjugated

Gene

C1orf106

Gene Alias

1700034M08Rik; 4933426C09Rik; 5730559C18Rik; AI586180; C1orf106; chromosome 1 open reading frame 106; D1Mgi54; Inava; Innate immunity activator protein; RGD1311892; RIKEN cDNA 5730559C18 gene; similar to hypothetical protein FLJ10901; uncharacterized protein C1orf106; uncharacterized protein C1orf106 homolog

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

55765

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Expressed in peripheral macrophages and intestinal myeloid-derived cells, is required for optimal PRR (pattern recognition receptor)-induced signaling, cytokine secretion, and bacterial clearance
  • Upon stimulation of a broad range of PRRs (pattern recognition receptor) such as NOD2 or TLR2, TLR3, TLR4, TLR5, TLR7 and TLR9, associates with YWHAQ/14-3-3T, which in turn leads to the recruitment and activation of MAP kinases and NF-kappa-B signaling complexes that amplifies PRR-induced downstream signals and cytokine secretion (PubMed:28436939)
  • In the intestine, regulates adherens junction stability by regulating the degradation of CYTH1 and CYTH2, probably acting as substrate cofactor for SCF E3 ubiquitin-protein ligase complexes
  • Stabilizes adherens junctions by limiting CYTH1-dependent ARF6 activation (PubMed:29420262)
  • [UniProt]

Compare Similar Items

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Img

Thermo Scientific

PIMA526848

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Antigen:
INAVA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q3KP66

Gene Symbols:
C1orf106

Immunogen:
Human recombinant protein fragment corresponding to amino acids 1-270 of C1ORF106 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI6A6

Conjugate:
Unconjugated

Gene:
C1orf106

Gene Alias:
1700034M08Rik; 4933426C09Rik; 5730559C18Rik; AI586180; C1orf106; chromosome 1 open reading frame 106; D1Mgi54; Inava; Innate immunity activator protein; RGD1311892; RIKEN cDNA 5730559C18 gene; similar to hypothetical protein FLJ10901; uncharacterized protein C1orf106; uncharacterized protein C1orf106 homolog

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55765

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA526849

--


Antigen:
UBA52

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P62987

Gene Symbols:
UBA52

Immunogen:
Synthetic peptide corresponding to residues near C-terminus of UBA52.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4F2

Conjugate:
Unconjugated

Gene:
UBA52

Gene Alias:
60S ribosomal protein L40; CEP52; D8Ertd21e; Gm1863; HUB L40; HUBCEP52; L40; Large ribosomal subunit protein eL40; MGC127041; RPL40; RPS27A; Uba52; UBB; Ubc; Ubcep2; Ubiquitin; Ubiquitin A-52 residue ribosomal protein fusion product 1; ubiquitin and ribosomal protein L40; ubiquitin carboxyl extension protein 52; ubiquitin/60S ribosomal fusion protein; ubiquitin-52 amino acid fusion protein; ubiquitin-60S ribosomal protein L40; ubiquitin-CEP52; Unknown (protein for MGC:127041)

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7311

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA526850

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Antigen:
NR2C2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P49116

Gene Symbols:
NR2C2

Immunogen:
Human recombinant protein fragment corresponding to amino acids 1-241 of NR2C2 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1F3

Conjugate:
Unconjugated

Gene:
NR2C2

Gene Alias:
mKIAA4145; Mtr2r1; Nr2c2; Nuclear hormone receptor TR4; nuclear receptor subfamily 2 group C member 2; nuclear receptor subfamily 2, group C, member 2; nuclear receptor subfamily 2, group H, member 2; orphan nuclear receptor TAK1; Orphan nuclear receptor TR4; orphan receptor TR4; orphan receptor, TR4; Tak1; testicular nuclear receptor 4; testicular receptor 4; TR2R1; Tr4; TR4 orphan receptor; TR4-NS orphan receptor

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7182

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA526851

--


Antigen:
NR2C2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P49116

Gene Symbols:
NR2C2

Immunogen:
Human recombinant protein fragment corresponding to amino acids 1-241 of NR2C2 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1B1

Conjugate:
Unconjugated

Gene:
NR2C2

Gene Alias:
mKIAA4145; Mtr2r1; Nr2c2; Nuclear hormone receptor TR4; nuclear receptor subfamily 2 group C member 2; nuclear receptor subfamily 2, group C, member 2; nuclear receptor subfamily 2, group H, member 2; orphan nuclear receptor TAK1; Orphan nuclear receptor TR4; orphan receptor TR4; orphan receptor, TR4; Tak1; testicular nuclear receptor 4; testicular receptor 4; TR2R1; Tr4; TR4 orphan receptor; TR4-NS orphan receptor

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7182

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid