PIMA526932

Kindlin 3 Monoclonal Antibody (OTI2G2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA526932-Each-of-1 In Stock ₹ 50,180.94

PIMA526932 - Each of 1

₹ 50,180.94

In Stock

Quantity

1

Base Price: ₹ 50,180.94

GST (18%): ₹ 9,032.569

Total Price: ₹ 59,213.509

Antigen

Kindlin 3

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q86UX7

Gene Symbols

Fermt3

Immunogen

Human recombinant protein fragment corresponding to amino acids 259-528 of FERMT3 produced in E.coli

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI2G2

Conjugate

Unconjugated

Gene

Fermt3

Gene Alias

C79673; fermitin family homolog 3; fermitin family homolog 3 (Drosophila); fermitin family member 3; Fermt3; Kind3; kindlin 3; Kindlin3; Kindlin-3; MGC10966; MIG-2; MIG2B; MIG2-like protein; RGD1310168; UNC-112 related protein 2; UNC112C; unc-112-related protein 2; URP2; URP2SF

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

83706

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • The three KINDLINs are a novel family of focal adhesion proteins, localizing to integrin adhesion sites
  • The KINDLIN proteins are composed of a centrally located FERM domain interrupted by a pleckstrin homology (PH) domain
  • KINDLIN1 and KINDLIN2 have been shown to play an essential role in integrin-mediated adhesion and spreading
  • In contrast to the widely expressed KINDLIN1 and KINDLIN2, KINDLIN3 is restricted to hematopoietic cells and is particularly abundant in megakaryocytes and platelets
  • Several reports describe a transcriptional misregulation of KINDLINs in various types of cancer
  • A recent study demonstrates that KINDLIN3 is essential for platelet integrin activation and subsequent integrin outside-in signaling, suggesting it may serve as a potential target for the design of therapeutics aimed at specifically disrupting integrin activation in platelets and leukocytes.

Compare Similar Items

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Img

Thermo Scientific

PIMA526932

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Antigen:
Kindlin 3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q86UX7

Gene Symbols:
Fermt3

Immunogen:
Human recombinant protein fragment corresponding to amino acids 259-528 of FERMT3 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2G2

Conjugate:
Unconjugated

Gene:
Fermt3

Gene Alias:
C79673; fermitin family homolog 3; fermitin family homolog 3 (Drosophila); fermitin family member 3; Fermt3; Kind3; kindlin 3; Kindlin3; Kindlin-3; MGC10966; MIG-2; MIG2B; MIG2-like protein; RGD1310168; UNC-112 related protein 2; UNC112C; unc-112-related protein 2; URP2; URP2SF

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
83706

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA526933

--


Antigen:
FOLR2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P14207

Gene Symbols:
FOLR2

Immunogen:
Human recombinant protein fragment corresponding to amino acids 20-221 of FOLR2 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4G6

Conjugate:
Unconjugated

Gene:
FOLR2

Gene Alias:
BETA-HFR; FBP; FBP/PL-1; Fbp2; folate binding protein; folate binding protein 2; folate receptor 2; folate receptor 2 (fetal); folate receptor beta; folate receptor, beta; folate receptor, fetal/placental; Folate-binding protein 2; folate-binding protein, fetal/placental; Folbp2; Folbp-2; FOLR2; FR-beta; FR-P3; placental folate-binding protein

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2350

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA526935

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Antigen:
A26C2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q6S5H5

Gene Symbols:
POTEG

Immunogen:
Full length human recombinant protein of POTEG produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2G1

Conjugate:
Unconjugated

Gene:
POTEG

Gene Alias:
A26C2; ACTBL1; ANKRD26-like family C member 2; ANKRD26-like family C, member 2; cancer/testis antigen family 104, member 4; CT104.4; POTE ankyrin domain family member G; POTE ankyrin domain family, member G; POTE14; POTE-14; POTE14alpha; POTE22; POTEG; Prostate, ovary, testis-expressed protein on chromosome 14; protein expressed in prostate, ovary, testis, and placenta 14

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
404785

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA526936

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Antigen:
SDHB

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P21912, P21913, Q9CQA3

Gene Symbols:
Sdhb

Immunogen:
Full length human recombinant protein of SDHB produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3F5

Conjugate:
Unconjugated

Gene:
Sdhb

Gene Alias:
0710008N11Rik; CWS2; fj46d06; FLJ92337; I79_022285; Ip; iron-sulfur subunit; iron-sulfur subunit of complex II; OTTHUMP00000044624; PGL4; SDH; SDH1; SDH2; Sdhb; SDHB protein; SDHB; sdhB; SDHIP; succinate dehydrogenase [ubiquinone] iron-sulfur subunit; Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; succinate dehydrogenase complex iron sulfur subunit B; succinate dehydrogenase complex subunit B; succinate dehydrogenase complex subunit B, iron sulfur (Ip); succinate dehydrogenase complex, subunit B, iron sulfur (Ip); succinate dehydrogenase Ip subunit; succinate dehydrogenase iron-protein subunit; wu:fj46d06

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
298596, 6390, 67680

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid