PIMA527176

TRMT12 Monoclonal Antibody (OTI1C9), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA527176-Each-of-1 In Stock ₹ 50,180.94

PIMA527176 - Each of 1

₹ 50,180.94

In Stock

Quantity

1

Base Price: ₹ 50,180.94

GST (18%): ₹ 9,032.569

Total Price: ₹ 59,213.509

Antigen

TRMT12

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q53H54

Gene Symbols

TRMT12

Immunogen

Full length human recombinant protein of TRMT12 produced in E.coli

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI1C9

Conjugate

Unconjugated

Gene

TRMT12

Gene Alias

4632406N01Rik; AI449275; alpha-amino-alpha-carboxypropyl transferase TYW2; homolog of yeast tRNA methyltransferase; TRM12; Trmt12; tRNA methyltranferase 12; tRNA methyltranferase 12 homolog; tRNA methyltransferase 12; tRNA methyltransferase 12 homolog; tRNA wybutosine-synthesizing protein 2 homolog; tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase; tRNA-yW synthesizing protein 2; tRNA-yW-synthesizing protein 2; TYW2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

55039

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • TYW2, also known as TRM12, is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway
  • Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome
  • TYW2 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation
  • TYW2 was found to be amplified in 7 of 8 breast cancers cell lines analyzed, and qPCR analysis of 30 breast tumors showed overexpression of TYW2 mRNA of over 2-fold in 26, suggesting that TYW2 may play a role in breast cancer.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA527176

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Antigen:
TRMT12

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q53H54

Gene Symbols:
TRMT12

Immunogen:
Full length human recombinant protein of TRMT12 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1C9

Conjugate:
Unconjugated

Gene:
TRMT12

Gene Alias:
4632406N01Rik; AI449275; alpha-amino-alpha-carboxypropyl transferase TYW2; homolog of yeast tRNA methyltransferase; TRM12; Trmt12; tRNA methyltranferase 12; tRNA methyltranferase 12 homolog; tRNA methyltransferase 12; tRNA methyltransferase 12 homolog; tRNA wybutosine-synthesizing protein 2 homolog; tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase; tRNA-yW synthesizing protein 2; tRNA-yW-synthesizing protein 2; TYW2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55039

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA527177

--


Antigen:
TRMT12

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q53H54

Gene Symbols:
TRMT12

Immunogen:
Full length human recombinant protein of TRMT12 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI5C9

Conjugate:
Unconjugated

Gene:
TRMT12

Gene Alias:
4632406N01Rik; AI449275; alpha-amino-alpha-carboxypropyl transferase TYW2; homolog of yeast tRNA methyltransferase; TRM12; Trmt12; tRNA methyltranferase 12; tRNA methyltranferase 12 homolog; tRNA methyltransferase 12; tRNA methyltransferase 12 homolog; tRNA wybutosine-synthesizing protein 2 homolog; tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase; tRNA-yW synthesizing protein 2; tRNA-yW-synthesizing protein 2; TYW2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55039

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA527180

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Antigen:
ACVRL1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P37023

Gene Symbols:
ACVRL1

Immunogen:
Human recombinant protein fragment corresponding to amino acids 22-119 of ACVRL1 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI5C2

Conjugate:
Unconjugated

Gene:
ACVRL1

Gene Alias:
activin A receptor like type 1, activin A receptor type II-like 1, activin A receptor type IL, activin A receptor, type II-like 1, activin A receptor, type II-like kinase 1, Activin receptor like kinase 1, activin receptor-like kinase 1, activin receptor-like kinase-1, Acvrl1, Acvrlk1, AI115505, AI427544, ALK1, ALK-1, HHT, HHT2, ORW2, R3, R-3, Serine/threonine-protein kinase receptor R3, SETHKIR, SKR3, TGF-B superfamily receptor type I, TSR-I

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
94

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA527181

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Antigen:
LHX4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q969G2

Gene Symbols:
LHX4

Immunogen:
Human recombinant protein fragment corresponding to amino acids 1-260 of LHX4 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1C7

Conjugate:
Unconjugated

Gene:
LHX4

Gene Alias:
A330062J17Rik; CPHD4; Gsh4; Gsh-4; Lhx4; LIM homeo box protein 4; LIM homeobox 4; LIM homeobox protein 4; LIM/homeobox protein Lhx4; LXH4

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
89884

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid